Leiden chemists discovered a new mechanism which might explain how multiple sclerosis shifts to a more severe form. Their findings contribute to unravelling the mysterious course of the disease. They have published their findings in the journal Biochemistry.

Cognitive decline (amongst other problems with attention, concentration, memory) is a common symptom in patients with a variety of brain disorders and has been related to healthy ageing as well. People suffering from cognitive deficits are often significantly hampered in their day-to-day functioning…

Neurodegenerative diseases pose a large medical and societal challenge. The etiology of these diseases is still poorly understood, which makes drug discovery for these diseases difficult.

How do fats and enzymes in the brain contribute to multiple sclerosis? In his PhD research, Daan van der Vliet combined chemistry and neuroscience to gain new insights into how brain disorders develop.