2,453 search results for “organisms chemistry” in the Public website
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eLaw students organize lecture by the European Data Protection Supervisor
On Tuesday 11 February, the European Data Protection Supervisor, Mr. Wojciech Wiewiórowski, visited eLaw, - center for Law and Digital Technologies at Leiden Law School to give a lecture on facial recognition systems and data protection in Europe.
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Aleydis Nissen wins the European Public Law Organization Thesis Prize
The postdoc received the 2020 Thesis Prize for her PhD research on the role of the EU Member States in regulating and remedying corporate human rights violations.
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In Memoriam: Robert Louw 1936-2023
On 18 February 2023, our esteemed former colleague Robert Louw passed away. Rob was 86 years old.
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The important role of stratum corneum lipids for the cutaneous barrier function
The skin protects the body from unwanted influences from the environment as well as excessive water loss. The barrier function of the skin is located in the stratum corneum (SC).
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Chemical synthesis of fragments of galactosaminogalactan and pel polysaccharides
The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.
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Education
Education & outreach
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Measurement of the average mass of proteins adsorbed to a nanoparticle by using a suspended microchannel resonator
SMR can be used to measure the mass of adsorbed protein to nanoparticles with a high precision in the presence of free protein.
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Book: The Colours of Energy
Huub de Groot is one of the 55 authors for the book The Colours of Energy. The book consists of Essays on the Future of Energy in Society in which leading energy thinkers explore the future of energy in society.
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Opening of new DNA-GER research network
On October 26, the Dutch Embassy in Berlin celebrated the opening of a new research network for Dutch academics in Germany. Dutch minister of Education, Culture and Science Robbert Dijkgraaf gave the starting signal for this new initiative.
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Jeroen Codee wins the Carbohydrate Research Award 2017
For his significant original contributions in the field of carbohydrate research, chemist Jeroen Codee will be awarded the biennial Carbohydrate Research Award for Creativity in Carbohydrate Chemistry.
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The Use of Machine Learning in Public Organizations - an Interview with PhD Student Friso Selten
Friso Selten recently started a PhD position that is part of the SAILS program. This PhD project is a collaboration between FGGA, LIACS, and eLaw, and is supervised by Bram Klievink (FGGA), Joost Broekens (LIACS), and Francien Deschene (eLaw). In the project Friso will investigate the influence of artificial…
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Fernando BordinFaculteit der Rechtsgeleerdheid
f.bordin@law.leidenuniv.nl | 071 5272727
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‘A donor organ is a precious gift that we should treat with care’
Professor André Baranski is a champion for improving organ procurement. He believes there should be standardised training and certification for procurement surgeons. This is what he said in his inaugural lecture on 16 April.
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Unconventional fabrication of 2D nanostructures and graphene edges
In this work, we illustrate unconventional approaches towards the fabrication of edge functionalized graphene nanostructures and bidimensional architectures in polymeric and metallic supports, with an outlook towards molecular sensing devices.
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Minute molecular movements might lead to more efficient biofuel cells
Leiden researchers have found minute movements in the laccase enzyme. This discovery could lead to the development of much more efficient biofuel cells. Publication in Biophysical Journal.
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Exo-planets, star and planet formation
At Leiden Observatory, researchers investigate the origin of stars and their planetary systems. They detect and characterize planets around other stars, which are called exo-planets. They study how stars and planets form. And they follow molecules from interstellar clouds to nascent planet systems.…
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International Labour Organization: tumult on the global labour market
Since 1919 the International Labour Organization (ILO) has been promoting the rights of workers worldwide. On 7 February, Leiden University hosted the symposium celebrating the 100-year anniversary of the foundation of the ILO. Leiden emeritus professor of International Labour Law Paul van der Heijden…
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Programme structure
The High-Tech Innovation specialisation consists of a 60 EC track alongside the students' core MSc programme: Astronomy, Chemistry, Computer Science, Mathematics and Physics.
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Teaching
At Molecular Physiology we teach the following courses within the Leiden Institute of Chemistry's Chemistry and Life Science and Technology programmes.
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Design and synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…
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Fundamental Research in Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
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Bert Meijer reappointed to the Board of Governors
Professor Bert Meijer has been reappointed as a member of Leiden University’s Board of Governors by the Minister of Education, Culture and Science, Ingrid van Engelshoven.
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TOP-PUNT grant awarded to prof. Gijs van der Marel
NWO Chemical Sciences has awarded a TOP-PUNT grant to a research proposal of prof. dr. Gijs van der Marel (Leiden University) and prof. dr. ir. Adriaan Minnaard (University of Groningen).
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Stewart McDowallFaculty of Science
s.c.mcdowall@cml.leidenuniv.nl | 071 5272727
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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Erik van GeestFaculty of Science
e.p.van.geest@lic.leidenuniv.nl | 071 5272727
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Career prospects
With a MSc in Chemistry you are well prepared for a wide range of career opportunities. The chemical industry is one of the largest contributors to economic prosperity worldwide.
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Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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'Historians Without Borders. Writing Histories of International Organizations'
This workshop intends to bring together early-career researchers from different fields working on international organizations, to discuss methodological challenges together with peers and established scholars. A combination of a master class, keynote lectures, and roundtable discussions aims at providing…
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Programme structure
In the MSc Chemistry programme you will focus your studies on one of LIC's two main research areas, Chemistry for Health or Chemistry for Sustainability, and one specialisation.
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Chemical functionalization of the graphene surface for electrical and electrochemical sensing application
Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.
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NWO TOP grants for two Leiden chemists
Using photosynthesis to generate energy, or using enzymes to effectively produce biofuel; Leiden chemists Huub de Groot en Hermen Overkleeft have both obtained an NWO TOP funding for their pioneering research. With the money they can take on new PhD students.
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About the programme
If you are interested in Life Science and you are looking for a programme with ample opportunities to put together your own study path, our Life Science and Technology programme is the right choice. The programme focuses on societal problems at the molecular and cellular level.
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Berend GagesteinFaculty of Science
b.gagestein@lic.leidenuniv.nl | 071 5274410
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The Europa Institute organizes online case law dinner on the German PSPP-judgment
Earlier this month, the Europa Institute organized an internal discussion on the German PSPP-judgment. For the first time, the German Constitutional Court declared acts of EU institutions as manifestly excessive and thus as ultra vires acts under German constitutional law. During an online debate, various…
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The environmentally-regulated interplay between local three- dimensional chromatin architecture and gene expression
Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.
- Elastin-like polypeptide micelles for vaccine delivery
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Role of near-surface environment in tuning electrochemical CO2 reduction reaction and H2 evolution reaction
This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…
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Beyond the Born-Oppenheimer Static Surface Model for Molecule- Surface Reactions
Several techniques are explored for going beyond the born-oppenheimer static surface model for molecule-surface reactions.
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RESTORING T-CELL HOMEOSTASIS BY IN VIVO MANIPULATION OF DENDRITIC CELLS
The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…
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Temperature and pressure effects on the electrochemical CO2 reduction
In eight chapters, the thesis of Rafaël Vos covers the effect of temperature and pressure on the electrochemical CO2 reduction.
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Development of homogeneous catalysts for the selective conversion of levulinic acid to caprolactam
Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent
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Graphene transmembrane nanofluidic devices: Fabrication strategies and ion transport
This dissertation was to develop effective graphene-based nanofluidic devices by developing scalable fabrication methods and elucidating proton transport mechanisms.
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Ab Initio Molecular Dynamics Calculations versus Quantum-State-Resolved Experiments on CHD3 + Pt(111): New Insights into a Prototypical Gas–Surface
The dissociative chemisorption of methane on metal surfaces is of fundamental and practical interest, being a rate-limiting step in the steam reforming process. The reaction is best modeled with quantum dynamics calculations, but these are currently not guaranteed to produce accurate results because…
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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mRNA and drug delivery with lipid-based nanoparticles
This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.
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Inverse design of curvature-sensing antiviral peptides
Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.
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State-resolved studies of CO2 gas-surface reactions
The adsorption of D2 and CO2 on catalyst surfaces is studied using a molecular beam in ultra-high vacuum.