High-throughput holistic preclinical screens are increasingly used in drug discovery, to assess both drug efficacy and drug safety.

The Leiden Institute of Chemistry actively participates in several national research schools for MSc and PhD students. These schools are consortia that stimulate collaboration between research groups of the different participating Dutch universities. The research schools also offer advanced training…

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof. dr. A.H. Meijer

Entry requirements for students with a degree from a Dutch University of Applied Sciences (HBO)

After 20 years of police reform, Jasper De Paepe and Marleen Easton look back and discover what we can learn about partnerships between police and science in Belgium.

The applications of studying the early development of insects range from agriculture to material science.

Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Research in this group, headed by Gerard van Westen, focusses on computational methods integrated in different parts of the drug discovery process. More specifically, topics include innovative treatments for cancer, selectivity modeling, translational research, allosteric modulation, drug resistance…

On 20 September 2019, the opening drinks for the Open Science Community Leiden will be held at the Faculty of Social and Behavioural Sciences. Open science is the approach to science aimed at making scientific research accessible, reproducible, and freely available to people within and outside the academic…

Investigating the contribution of interpreters, informants, hunters and guides in the making of colonial scientific knowledge.

Source: Mol Pharmacol, Volume 87, Issue 2, pp. 305-13 (2015)

In the past decade many population studies have been performed with the Atacama Large Millimeter/submillimeter Array (ALMA) to understand the bulk properties of protoplanetary disks around young stars. These population studies mostly consisted of low mass stars, with relatively few of the disks around…

The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.

What are the phylogenetic relationships among the members of speciation bursts?

Our research aims to develop drugs that boost the host immune response to better defend us against mycobacteria.

Promotor: J. Schaye

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

This thesis explores how electron paramagnetic resonance (EPR) spectroscopy can be used to investigate key biochemical processes.

Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.

Promotor: Prof.dr. P.C. van Welzen

Do you have questions about the specialisation Molecular, Cellular and Organismal Biology? Please contact us.

Do you have questions about the master’s specialisation Molecular Genetics and Biotechnology? Please contact us.

Are you curious about how science and technology contribute to a sustainable and innovative future? At Leiden University, you’ll explore the world of data, natural laws and living systems. From mathematics to artificial intelligence, from climate challenges to high-tech innovation: you’ll learn to analyse…

Are you curious about how science and technology contribute to a sustainable and innovative future? At Leiden University, you’ll explore the world of data, natural laws and living systems. From mathematics to artificial intelligence, from climate challenges to high-tech innovation: you’ll learn to analyse…

Identifying natural plant-associated bacteria that provide targeted inhibition of pathogens through the production of antimicrobial peptides.

Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink

We investigate reaction systems, a novel computational model gleaned from the biochemical reactions taking place in living cells and information processing in nature.

Find out how to apply for Molecular Genetics and Biotechnology at Leiden University by following our step-by-step guide.

Find out how to apply for Molecular, Cellular and Organismal Biology at Leiden University by following our step-by-step guide.

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

Learning from nature and utilizing microbial biodiversity to identify and characterize enzymes for degradation and upcycling of plastics and other polymeric materials.

To improve treatment of breast cancer patients it is important to understand all stages of breast cancer from initiation to in situ disease and progression to invasive disease. In this thesis we use intraductal injections of patient derived tissue to model ductal carcinoma in situ and invasive breast…

PhD at Molecular Biology and Biochemistry Department, University of Malaga - Spain

PBDL favors multidisciplinary research. Depending on the problems under investigation, PBDL establishes collaborations between experts from for example molecular genetics, molecular and electro cell physiology, biochemistry, organic chemistry, analytical mathematics, mathematical statistics and computational…

Most degree programmes at the Faculty of Social and Behavioural Sciences are based in the Pieter de la Court building on the Wassenaarseweg in Leiden. Besides this location, some degree programmes are based in The Hague, at Campus The Hague’s Wijnhaven building.

Leiden biotech startup Azafaros has successfully completed a funding round, raising 25 million euros of investments for developing treatments of rare metabolic disorders. The company holds exclusive license to a library of novel patented compounds discovered by experts from Leiden University.

How can efficient chemical synthesis and clinical microbiology be combined to identify new antibiotics against Clostridioides difficile infections?

The challenge: Building a tool to detect chemical compounds that individually cause non-lethal stress to bacteria, but that are lethal in combination. A team of thirteen Leiden students are taking up this challenge in the annual ‘international Genetically Engineered Machine’ (iGEM) competition for applications…

PhD defence