Africa is online. Leiden Africa expert Mirjam de Bruijn is fascinated by the fast development of mobile telephony and social media in Africa. She maintains a website on the topic, focusing on isolated, marginalised and conflict-ridden areas in Middle Africa.

It’s been a turbulent, bizarre and extraordinary year, 2020. Coronavirus turned the lives of everyone at our University upside down. Out teaching, research and all the events that are held in a year: nothing was the same as before. That this affected all of us is clear from the highlights and many reactions…

The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Cell Systems and Drug Safety, Medicinal Chemistry and Systems Pharmacology and Pharmacy, and the Metabolomics and Analytics Centre.

On 4 and 5 September, Leiden Law School hosted a special conference that brought together around sixty participants from the Netherlands and abroad to discuss the future of economic, social, and cultural rights – rights that touch upon everyone’s daily life: housing, education, healthcare, food, and…

A 5 million euros grant from the Dutch Research Agenda allows Anouk de Koning and co-applicants Femke Kaulingfreks and Maartje van der Woude to study social interventions in eight Dutch cities in an innovative and interdisciplinary way.

We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.

This project investigates how robot testing facilities could help to optimize the regulation for robot technologies.

In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.

Supervisor: Natalia Ortiz Zacarías

In June the Final Festival took place, the closing event of the 'Social Science Lab'. New participants of Honours College Science and Society presented their solution for a current social problem.

Compare human social behaviour at a country level and you will find differences. Japan has the highest score whereas the Netherlands is just above average. This is what psychologist Niels van Doesem discovered in research with an international team of 64 colleagues in 31 industrialised countries. Their…

Leiden University has a new Executive Board. Since 8 February 2021, Annetje Ottow has been the new President and Hester Bijl the new Rector Magnificus of the Board, while Martijn Ridderbos has continued in his role as Vice-Chairman.

During the event 'Fout?' by De Jonge Akademie, Ellen de Bruijn held a lecture about the social context of making mistakes and the psychological elements of learning from it.

Would you like to know more about our research using laboratory animals or our studies on alternatives to animal testing? If so, take a look at the news articles on the right-hand side of the page (for mobile users, see the bottom of the page).

Promotores: J. Jonkers, K.E. de Visser

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

Source: J Med Chem (2015)

ChEMBL is a large-scale drug discovery database containing bioactivity information primarily extracted from scientific literature.

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

Developing new medicines is one of modern science's most significant hurdles, a process marked by high costs, long timelines, and frequent failures of promising candidates.

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.

Agricultural foods naturally vary in their detailed internal structure. To facilitate early detection of health hazards due to contamination or disease, predict maturity and minimize wastage, it is critical to take into account the internal characteristics of each individual product, as these enable…

Structure-affinity relationship (SAR) and structure-kinetics relationship (SKR) studies were combined to investigate a series of biphenyl anthranilic acid agonists for the HCA2 receptor.

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.

Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…

The multidisciplinary minor The (Un)just Society explores social justice in the Netherlands. You examine issues such as poverty, discrimination, housing shortages, climate, and migration from various perspectives. Through practical assignments and reflection on your own role in society, you actively…

ERC StG SAFE and SOUND has the ambition to connect the policy cycle with data generated in robot testing zones to support evidence-based policymaking for robot technologies.

Monday 26 September, 2016 saw the first confrontation between Hillary Clinton and Donald Trump. Expectations were high – not only about the content of the debate, but also about how the two presidential candidates would behave, and how this might influence their campaigns. We asked three researchers…

As young people’s friendships improve, their mental resilience also increases. This is according to research conducted by Anne-Laura van Harmelen, Professor of Brain, Safety and Resilience at Leiden University.

Could policies aimed at preventing radicalisation undermine the very trust and social cohesion they aim to strengthen?

The new minor ‘The (un)just society’ will start in September 2024. We asked Judi Mesman some questions about this new minor.

Organised jointly by the Europa Institute, Leiden University and the Lisbon Centre for Research in Public Law, University of Lisbon on 31 May 2021.

Vanessa de Malmazet has been working as HR policy advisor in FGGA's Faculty Office since March. Promoting employee well-being is high on the Faculty Board's list of priorities for the coming years. In this new role,

The Graduate School of the Faculty of Humanities conducted a survey of its PhD candidates and their supervisors in spring 2023. What is going well? And what could be improved? The results are now known.

eLaw – Center for Law and Digital Technologies has officially launched its participation in AI:Liner, a Horizon Europe project that will transform how Europe manages its aging sewer infrastructure through artificial intelligence and digital innovation.

The Social Resilience & Security interdisciplinary programme broadens its scope by embedding two research projects lead by Dr. Joanne Mouthaan. The projects adress suicide prevention skills and mental health of Ukraine refugees. Both projects will be integrated in the programme with the aim to improve…

Recent figures from Statistics Netherlands show that the total number of homicides has decreased in 2020. But the number of homicides among young people increased. Many have interpreted this to mean that homicide among teenagers in increasing. Marieke Liem, Professor of Social Resilience and Security,…

Veel Nederlanders hebben fysieke, psychische en sociale problemen tegelijk. Zij hebben hulp nodig van meerdere professionals uit verschillende organisaties. Fia van Heteren onderzoekt hoe deze professionals met elkaar én met cliënten samenwerken, en welke factoren deze samenwerking versterken of bel…

How do people living in a remote part of Northern Mongolia experience the post-socialist transition that occurred twenty years ago? Based on extensive fieldwork, cultural anthropologist Richard Fraser argues that this is not at all clear. In his PhD dissertation, he developed a new framework based on…

The Hague Journal of Diplomacy is hosted by the Institute of Security and Global Affairs at Leiden University. Besides the journal, there are many other activities related to diplomacy.

Eduard Fosch-Villaronga, Marie Skłodowska-Curie Postdoctoral Researcher at eLaw- Center for Law and Digital Technologies, just published a book on Robots, Healthcare, and the Law. Regulating Automation in Personal Care.

Understandably, coronavirus is often viewed from a medical perspective. However, researchers in the social sciences and humanities possess a great deal of expertise that could improve our understanding of the virus outbreak and its impact on society. A new portal is consolidating this knowledge.