The Division of BioTherapeutics at the Leiden Academic Centre for Drug Research (LACDR) is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

The Microscopy Unit houses, maintains and coordinates most of the microscopy equipment of the IBL. The available equipment ranges from conventional light and fluorescence microscopes, to confocal laser scanning and electron microscopes. In addition, infrastructure is available for histology, including…

Living systems scale from unicellular microbes to complex multispecies communities that constantly change over time. Within the theme Development & Disease, we enhance our fundamental understanding of development and homeostasis of living cells and systems. We analyze the normal situation and how stresses…

This is an Erasmus+ International Credit Mobility project of the Faculty of Science with the Ethiopian Space Science and Technology Institute in Ethiopia.

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with the University of Havana.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with two Colombian universities, Universidad Nacional de Colombia and Universidad de Antioquia.

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center and the Faculty of Science with two universities in Indonesia.

This is an Erasmus+ International Credit Mobility project of the Faculty of Science with Sichuan University in Chengdu.

Honorata Mazepus and Jaroslaw Kantorowicz are assistant professors at the Institute of Security and Global Affairs. Mazepus and Kantorowicz are one of the authors of this article in Nature on the role of national identity on public health support during global pandemics.

On 16 January 2020, Maaike Wensveen defended her thesis 'Eigen haard is goud waard?'. The doctoral research was supervised by Prof. P. Nieuwbeerta and Dr. J.M.H. Palmen.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Governance and Global Affairs with Fukushima University.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Social and Behavioural Sciences with Royal Thimphu College in Bhutan.

This is an Erasmus+ International Credit Mobility project of the Faculty of Sciences with one partner in Ukraine.

Arts and leisure, Arts and leisure

Psychology Lab on Wheels makes research accessible to all: with our mobile lab we literally reach people on the street. From bustling city centres to remote areas, our lab travels all over, making it easy for you to participate in our research. And with your help, we gain new insights and deepen our…

Rijpma was invited by the 'Netherlands Education Support Office' of the Dutch Organisation for the Internationalization of Education (Nuffic) to speak in Russia within the framework of their Dutch Science Talks.

Exactly 138 years ago, Albert Einstein came into this world to forever change our understanding of it. The Leiden physics institute, where he frequently worked, organised a symposium in honor of his birthday.

Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…

Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…

The work done by SUMO proteins in the cells of our body is of vital importance. Molecular cell biologist Alfred Vertegaal has been studying these proteins for nine years, first with a Veni subsidy and then with a prestigious Vidi subsidy.

Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…

The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…

Core Facilities are shared resources that provide access to instruments, technologies and services to researchers across the Institute of Biology. They are staffed by scientists with vast experience in their field, ensuring that all researchers can count not only on the latest available technology…

The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'

Psychology Lab on Wheels is available for rent for your on-site research. What does the mobile lab look like? What are the requirements? How do you make good use of the mobile lab?

This is an Erasmus+ International Credit Mobility project of Leiden Law School with Shandong University in Qingdao.

This is an Erasmus+ International Credit Mobility project of the Faculty of Science with the Taras Shevchenko National University of Kyiv.

Leiden University has awarded its prestigious University Medal to Emeritus Professor Lex van der Eb. As a pioneer in genetics and molecular biology, he received this honour for his services to science and his key role in the development of the Leiden Bio Science Park (LBSP).

On 9 February students of the Master in European Law visited the new headquarters of Eurojust, one of the EU’s agencies for judicial cooperation in criminal matters based in The Hague.

Three students of the Master programme in European Law have published a blog post on the Leiden Law Blog.

In the framework of his Jean Monnet Chair on Mobility and Security, Jorrit Rijpma has given a series lectures on EU migration and asylum law to the students of the interdisciplinary master on Governance of Migration and Diversity. This interdisciplinary master was set up in the framework of the Leiden…

How do lipases in Mycobacterium tuberculosis help the bacteria survive, and can we target them to create new antibiotics?

Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.

The CMCB comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC) and the Leiden University Medical Center (LUMC).

The discovery of new medicines is a tedious and lengthy process. On average, over 10,000 molecules need to be studied for one to become a drug and reach the patient. Part of that process are the very costly clinical trials in humans, and candidate drugs often fail due to side effects or lack of efficacy.…

NL-BioImaging AM is a distributed research infrastructure aimed at promoting progress in the most cutting edge microscopy technologies and providing open access to these technologies to a broad community of academic and industrial users. All Netherlands bio(medical) microscopy centers participate.

Can the conditioning paradigm be used for checkpoint inhibition cancer treatment?

By carrying out fundamental research and providing excellent education, universities become a breeding ground for innovation and entrepreneurship.

Research at the MCBIM group is comprised of the following research themes:

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

The ambition of the Metabolomics and Analytics Centre led by Thomas Hankemeier is to develop innovative analytical strategies for metabolomics-driven health monitoring and systems biology studies. Understanding the intricate balance between health, disease and adaptation to challenges relies on the…

We have recently discovered that there are biological proteins that phase separate out of solution much the way oil will de-mix from water (see movie). These form dense, liquid-like phases called protein condensates.

An overview of research themes and projects at ABS.

Artificial photosynthesis aims to produce fuels from solar energy using chemical processes. In semi-artificial photosynthesis, a hybrid approach is taken using both chemical and biotechnology components. We are developing hybrid systems, coupling light-harvesting nanoparticles to redox-enzymes (oxidoreductases)…

Our research in the area of safety sciences aims to increase the mechanistic understanding of cellular toxicity of drugs and, in a broader sense, chemicals.

This is an Erasmus+ International Credit Mobility project of the Faculty of Science and Leiden University College with four universities in Nigeria.

In the late 19th and early 20th century, hundreds of thousands of Chinese labor migrants crossed the seas to the Dutch East Indies. On the tobacco plantations of northeastern Sumatra and in the tin mines of Bangka and Belitung, they endured long hours and harsh conditions. Their journeys formed part…

This is an Erasmus+ International Credit Mobility project of the Faculty of Humanities with the Anton de Kom University in Paramaribo.

We are experts in the fields of languages, cultures, history, arts, societies and philosophy. Together we cover almost all continents and time periods. Knowledge of these disciplines contributes to a humane, safe and sustainable world.