2,653 search results for “development disease” in the Public website
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Cancer and heredity
Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.
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Environmental assessment and guidance for the future offshore wind energy development
This thesis aims to address offshore wind energy (OWE)-related environmental impacts.
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The development of molecular tools for investigating NAD+ metabolism and signalling
Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…
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New platform to accelerate cardiac drug development
Researchers from Leiden University Medical Center (LUMC) and the Leiden-based biotech company Ncardia have joined forces to develop a new platform that enables the automated production of 3D cardiac microtissues. This platform will allow large numbers of drugs to be tested quickly
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Resetting the immune system to cure diabetes and rheumatism
In autoimmune diseases such as rheumatism and diabetes the immune system attacks autologous proteins. Leiden researchers are trying to discover how this comes about.
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Janna Marie Bas-HoogendamFaculty of Social and Behavioural Sciences
j.m.hoogendam@fsw.leidenuniv.nl | 071 5276345
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About the programme
To maximise your personal development, we ensure tutorials are small-scale and staff members extremely accessible. In year one, you’ll have an average of 12 contact hours, half of which comprise lectures (in English) and the remainder tutorials (optionally Dutch or English).
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Area studies of the Minor Sustainable Development in four countries
Every January, students of the Minor Sustainable Development have the opportunity to put what they’ve learned over the last few months into practice in a choice of exciting and practical courses called Area Studies. This year, for the first time, there was a choice of four locations: The Netherlands,…
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Personalised sarcoma care: Leiden mathematicians develop a prediction app
The DASPO-group for data analysis and survival in personalized sarcoma at the Mathematical Institute has developed an app that provides personalised predictions for patients suffering from soft tissue sarcomas. Due to the aggressive nature of such tumors, the prognosis for such patients is poor, even…
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Partners
Our research programme collaborates with all kinds of partners to achieve our goal: bringing scientific discoveries to the clinic as soon as possible.
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Application procedure
Learn how to apply for the MSc in Nationalism, Ethnic Conflict and Development at Leiden University: step‑by‑step procedure, submission via Studielink, and next steps.
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Digitizing security: How digital risk-profiling is developed in practice
How are digital risk-profiles developed and used in practice?
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Development of novel anti-cancer strategies utilizing the zebrafish xenograft model
In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…
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D-lightful Sunshine Disrupted
This study stresses the importance of investigating vitamin D deficiency in every community to better understand the deteriorating effect that sociocultural practices may have had on health.
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Optimisation of first clinical studies in special populations: towards semi-physiological pharmacokinetic models
Promotor: M. Danhof, Co-promotores: J. Freijer, A. Yassen
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Kinetics for drug discovery – The first step towards an improved drug discovery paradigm
Supervisor: Indira Nederpelt
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Data Analytics and Management
Our group is part of the Metabolomics and Analytics Centre where we accompany the data from its acquisition all the way to the publication of identified associations and biomarkers for a range of human diseases. The generated data of the metabolic measurements are assessed using an in-house quality…
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Leiden University and LUMC strengthen ties with Janssen pharmaceutical company
Leiden University, the LUMC and Janssen have signed a partnership agreement stating that they will collaborate in different areas, including infectious disease prevention, clinical tests, drug production and e-health. By joining forces, the three partners will be able to provide better, more innovative…
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Subang: An Indigenous Institution for Sustainable Community-Based Development in the Sunda Region of West Java, Indonesia
This study attempts to understand how indigenous community institutions pose an important role in sustainable community-based development, including the integration between local culture and development.
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and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries)
The Power and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries) investigates the development of General Average and other so-called Averages in the Low Countries on the eve of the early modern period, showing how the various varieties…
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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Interview with the Programme Director
“How we will tackle diseases in the future starts here”
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Religion, Class, and the Postwar Development of the Dutch Welfare State
Religion, Class, and the Postwar Development of the Dutch Welfare State. Dennie Oude Nijhuis.
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European foreign policy in times of crisis: a political development lens
EU foreign policy has become increasingly politicised over the past years, amongst others as a consequence of the succession of crises. Crises may engender processes of crisis framing and contestation. This article focuses on how the policy demands being voiced in these processes of contestation are…
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Life Course
As a result of an increased life expectancy, more people suffer from chronic diseases and discomfort. Elderly patients may have multiple diseases simultaneously, with concomitant multiple medications.
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Research projects
An overview of research projects at the Predictive Pharmacology group.
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Ayokunu AdedokunFaculty of Governance and Global Affairs
a.b.adedokun@luc.leidenuniv.nl | 070 8009503
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Jonathan PhillipsFaculty of Social and Behavioural Sciences
j.p.phillips@fsw.leidenuniv.nl | 071 5272727
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Bert KoendersFaculty of Governance and Global Affairs
a.g.koenders@fgga.leidenuniv.nl | 070 8009500
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Paul van den BroekFaculty of Social and Behavioural Sciences
p.vandenbroek@fsw.leidenuniv.nl | 071 5272727
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Alette VonkFaculty of Humanities
a.p.vonk@hum.leidenuniv.nl | 071 5272746
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Chris RiddellFaculty of Social and Behavioural Sciences
c.d.riddell@fsw.leidenuniv.nl | 071 5272727
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The role of hearing signers in the development of channel specific structures in sign languages of deaf communities
In this project, the hypothesis that language contact crucially impacts the development of spatial grammar and phonology is investigated.
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Surya Tjandra defends his Ph. D thesis ‘Labour Law and Development in Indonesia’ on 4 February 2016
In his thesis Tjandra analuses the development of labour law in Indonesia. He focusses on the developments after the fall of the Soeharto regime (1998), the so called reformasi period.
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Knowledge development of secondary school L1 teachers on concept-context rich education in an action-research setting
This thesis reports on a study that examined the development of L1 teachers’ practical knowledge when they researched and implemented concept-context rich education in an action-research setting.
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Cell Observatory: visualising structures of life
From molecule, to cell, to organism. The high-level drug research at the Cell Observatory aimes at reducing the spread of cancer and developing new medicines for tuberculosis.
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New Methods for (f)MRI Analysis
Analysis of neuroimaging data requires multiple steps where statistics play a crucial role. The MRI methods research group develops new statistical methods that are accurate, transparent and easy to use.
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Half a million euros to develop better and cheaper MRI scanners
Professor Andrew Webb has been appointed Simon Stevin Master 2017 by the Netherlands Organisation for Scientific Research, an award that carries a prize of 500,000 euros. Webb, who is Professor of MRI Physics at Leiden University Medical Center (LUMC), will use this funding to focus on developing new…
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Education
The Faculty of Archaeology at Leiden University offers education in Human Osteoarchaeology. We offer a second-year Bachelor course in Human Osteoarchaeology and an extensive one-year track in the Master’s in Archaeological Science specialisation, resulting in a Master of Science degree after complet…
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Leiden Institute of Chemistry
The Leiden Institute of Chemistry (LIC) is the basis for research and collaborations of the Leiden chemistry groups. Chemistry is the central science enabling a healthy future in a sustainable society. Chemistry researchers at Leiden University take a fundamental approach in finding tailored solutions…
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Research lines
Current research at the Skin Barrier and Vaccination group.
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Amanda Foks receives Dekker grant from Dutch Hartstichting
Pharmacologist Amanda Foks is one of the ten talented scientists who received a Dekker grant from the Hartstichting. She receives €427,000 to find a way to rejuvenate immune cells to prevent infarcts. Foks was nominated as Discoverer of the Year in 2016.
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The Mastermind approach to brain research
The brain is a complex organ, and researching medicine to treat brain disorders is equally if not more complex. Elizabeth (Liesbeth) de Lange, Professor of Predictive Pharmacology, calls for a structured approach. ‘In effect, it's like playing Mastermind.’ Inaugural lecture on 22 March.
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Pharmacological resting-state fMRI in aging and dementia
How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?
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The synthesis of chemical tools for studying sphingolipid metabolism
Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of sphingolipids, but interruption of this metabolism process leads to different diseases.
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Host-Microbe Interactions in Microbial Sciences
Microbial Sciences' contribution to the Host-Microbe Interactions research theme is to investigate how beneficial or disease-causing microbes associate and interact with their host.
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: Prof.dr. T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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Contact
Contact us about initial teacher education, educational research and teacher professional development