3,072 search results for “cell mobility” in the Public website
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Opening a Bank Account
It is advisable to open Dutch bank account once you move to The Hague (if you do not have one already), as it will allow you to get many other services such as a mobile phone contract, transportation, etc.
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Jorrit Rijpma opens calendar year with the Meijers Lecture
On 12 January 2018 Jorrit Rijpma, associate professor of the Europa Institute and Jean Monnet Professor, held the yearly Meijers lecture. In the well-attended lecture he spoke on the topics of his Jean Monnet Chair on Mobility and Security: the aftermath of the refugee crisis and the effects on free…
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Ensnaring tumours in their own web
Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.
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Armenia
This is an Erasmus+ International Credit Mobility project of the Faculty of Science with two universities in Armenia.
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South Africa
This is an Erasmus+ International Credit Mobility project of the Faculty of Science with the University of Pretoria.
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Kazakhstan
This is an Erasmus+ International Credit Mobility project of ICLON (Leiden University Graduate School of Teaching) with four partners in Kazakhstan.
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Cheianov Group - Quantum Many Body Physics in Condensed Matter and Ultracold Atomic Systems
The research in my group addresses a range of topics related to quantum many-body physics.
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How metastatic tumours manipulate their environment
Tumours act like mini-organs, manipulating their environment and using bodily processes to survive and metastasise. Through research by Erik Danen and his colleagues, we are learning more about the complex nature of tumour cells. In the Dutch newspaper NRC, the scientists discuss their findings.
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Physics and Engineering Approaches to Biomedicine and Pharmacology
Mashaghi lab conducts research at the interface of physics, engineering and biomedicine. We develop and use theoretical and experimental approaches to address basic and applied research problems.
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Discoveries at Leiden Science
From the largest numbers to the smallest molecules and from the oldest galaxies up to the latest algorithms, explore our standout discoveries and most inspiring collaborations from the past year!
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Factors affecting galanthamine production in Narcissus
Factors affecting galanthamine production in Narcissus
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Chemical tools to study the cannabinoid receptor type 2
The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…
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Protein Facility
The Protein Centre can supply you with purified proteins that are essential for many experiments, ranging from in vitro inhibitor screening and enzymatic analysis to manipulation of life cells.
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Unraveling the role of signaling networks controlled by Grainyhead like transcription factor in breast cancer subtypes
This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…
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Contact
Division contact information & address
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Dario BijkerFaculty of Science
d.i.bijker@lacdr.leidenuniv.nl | 071 5272727
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Kostas TassisFaculty of Science
k.tassis@lacdr.leidenuniv.nl | 071 5276302
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Myrtille KoerselmanFaculty of Science
m.e.koerselman@lacdr.leidenuniv.nl | 071 5276270
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Marjolijn LugthartFaculty of Science
m.j.l.lugthart@lacdr.leidenuniv.nl | 071 5276270
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Nasi LiuFaculty of Science
n.s.liu@lacdr.leidenuniv.nl | 071 5276225
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Martijn MonéFaculty of Science
m.j.mone@lacdr.leidenuniv.nl | 071 5276105
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Matthijs VlasveldFaculty of Science
m.p.vlasveld@lacdr.leidenuniv.nl | 071 5272727
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Post-Soviet Nostalgia. Confronting the Empire's Legacies
Bringing together scholars from Russia, the United States and Europe, this collection of essays is the first to explore the slippery phenomenon of post-Soviet nostalgia by studying it as a discursive practice serving a wide variety of ideological agendas.
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Education
An overview of the courses
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Strategic Task Forces
Our staff and students serve on task forces that aim to translate key Una Europa themes into concrete actions.
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Freedom in Captivity: Negotiations of Belonging along Kashmir's Frontier
How do borderland dwellers living along militarised frontiers negotiate regimes of state security and their geopolitical location in everyday life? What might 'freedom' mean to those who do not resist captivity engendered by borders? Focusing on the predicaments of a double-minority, Radhika Gupta examines…
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Sustainability on campus
Duurzaamheid op de campus, energietransitie, groen, circulair
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(Un)timely Crises Chronotopes and Critique
This book explores how ‘crisis’ - as a narrative, concept, grammar, and experience - structures time and space.
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Contact
Contact Institute of Environmental Sciences (CML)
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Cannabinoid receptor 2 as a ‘drugable’ target: kinetic profile of novel receptor ligands
Supervisor: Andrea Martella
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Piecewise deterministic Markov processes: an analytic approach
Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans
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Chemical tools to monitor and control human proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
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NeCEN
With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…
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Key publications
Key publications of the Cancer Drug Target Discovery group
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Lipid bilayers decorated with photosensitive ruthenium complexes
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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The role of 14-3-3 proteins in ion homeostasis in the yeast Saccharomyces cerevisiae
We aim to understand ion homeostasis in the model eukaryote S. cerevisiae.
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Role of non-homologous end-joining in T-DNA integration in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater
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Zipping into Fusion
Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros
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Towards photo-CIDNP MAS NMR as a generally applicable enhancement method
Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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Macrophages and atherosclerotic lesions
Macrophages and atherosclerotic lesions The infiltration of monocytes in the arterial wall, their differentiation to macrophages, and the subsequent accumulation of cholesterol in these macrophages initiate the process of atherosclerosis. We study the importance of specific genes in macrophages for…
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François Mesnard
PhD at Université de Picardie Jules Verne, Amiens - France
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Master Projects
Master projects are available in
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Targeting Human Proteasomes: Substrates, Inhibitors and Prodrugs
Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska
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The Netherlands X-omics Initiative
The Netherlands X-omics Initiative is a new facility as part of the National Roadmap for Large-Scale Research Infrastructures. It is partly funded by NWO with a total budget of 40 million euro. The project started on September 2018 and will last for ten years.
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Kinetics for drug discovery – The first step towards an improved drug discovery paradigm
Supervisor: Indira Nederpelt
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Drug discovery and development
New or improved treatments for chronic and acute illness.