Prof. Elizabeth de Lange is concerned with the allocation of resources for the conduct of science towards the goal of best serving the public interest. Also, while she underscores that there is still the need for using animals in drug research, she is concerned about this use, and advocates the use…

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.

This research cluster explores processes of cultural creation, reception and transformation within a wide range of societal contexts from the early Middle Ages until c. 1800.

Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange

A new research line is the development of liquid biopsy fingerprints to predict early Alzheimer’s disease (AD) stage in human in readily accessible body fluids in human (in collaboration with: Dr. Geert-Jan Groeneveld, CHDR; Prof. Elga de Vries, Free University Medical Center; and others).

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Lecture, Book presentation

The research project examines the site-specific event within the field of installation art and choreographic practices.

How can the importance of the image in late medieval spirituality be understood in the context of the love mysticism inspired by the imagery of the Song of Songs?

The Institute of Cultural Anthropology and Development Sociology is one of five research institutes of the Faculty of Social and Behavioural Sciences. The Institute is dedicated to high-quality, interdisciplinary education and research concerning culture and development.

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

Religion, Philosophy, and the Pre-modern World

Promotor: Prof.dr. J. Schaye, Co-promotor: Marcello Cacciato

Innovative Approaches by Junior Archaeological Researchers

The lack of success of new CNS drugs in clinical development is in part due to the complexity of the CNS, unexpected side effects, difficulties for drugs to penetrate the brain, but also by the lack of biomarkers.

Although rarely considered by the pharmaceutical industry or clinicians, 24-hour rhythms in physiology are a factor of potential influence on the pharmacokinetics and pharmacodynamics of drugs.

In the early modern period, it was perfectly normal to find recipes, legal documents or medical writings in a book of poems. PhD candidate Holly Riach studied the underlying principles of these ‘miscellanies’.

De spreidingswet die asielzoekers evenwichtig over gemeenten in Nederland moet verdelen en per 1 juli 2025 gereed moet zijn, staat onder druk. Mark Klaassen, universitair docent migratierecht, spreekt in EenVandaag over de zaak.

Foute taal? Bestaat niet!

A Leiden literary scholar, paintings of the Winter King and Queen and a string of pearls brought together by an exhibition in the Hague. Dr Nadine Akkerman: ‘The Winter Queen was a highly political person who used every means – including pearls - to showcase her royal lineage.’

Dr Nadine Akkerman, lecturer in Early Modern Literature and postdoctoral researcher in Leiden, has written a new book to accompany the exhibition on Elizabeth Stuart and Amalia von Solms at the Historical Museum of The Hague. ‘They were like goddesses, constantly trying to upstage one another,’ says…

‘Seated behind her desk, she initiated and influenced embassies, conventions, ambassadorial meetings, sieges, and skirmishes that had kept a war-torn early modern Europe in its grip.’ This is how Nadine Akkerman, researcher as the Leiden Institute for Cultural Disciplines and author of The Correspondence…

Covid-19 is een disruptieve ontwikkeling die hier en nu veel vraagt van zorgprofessionals, bestuurders en managers. Hoewel de crisis nog volop bezig is, is nu al duidelijk dat het Coronavirus een blijvende impact zal hebben op zorginstellingen en fundamentele vragen oproept over hoe we onze zorg optimaal…

Leiden University offers its students a wide range of bachelor's, master's and minors that explore sustainability or climate. Here, you find an overview of those programmes in the academic year 2020-2021.

On 1 September, the conference of the Kirchheiner Chair ‘Government and citizens: A matter of trust’ took place. In a packed hall in the beautiful Old Observatory of Leiden University, under the inspiring leadership of Willemien den Ouden, a debate was held on the role of the Dutch National Ombudsman,…

In the Faculty of Archaeology depots, many artefacts, accumulated after decades of fieldwork across the world are stored. The Leiden Inventory of the Depot (LID) project aims to unlock the door to this wealth of information. Elizabeth Hicks, a Research Master’s student at the Faculty, will be re-evaluating…

Sonorous phenomena are always on the verge of becoming something else. As it unfolds, sound constitutes spaces, mediates presence, articulates time. Furthermore, it may prompt emotions, generate awareness, organise patterns of behaviour or trigger a sense of belonging. As sound becomes audible, it is…

A next, general pharmacological problem to be tackled is how drug-target binding kinetics in vivo, affects target occupancy as an important indicator of the time-course of drug effects.

Indigenous Latin American artifacts have attracted the interest of Europeans since the earliest moment of contact between Europeans and the Indigenous peoples of the Americas. The ERC-funded BECACO project uses an innovative multidisciplinary framework to investigate the provenance of ethnographic and…

Meet the scientists within the LED3 community

Lecture, Blue History Network Graduate Forum

Coming four years after part II, and totalling more than one thousand pages, the long awaited first part of the Correspondence of Elizabeth Stuart (1596–1662), daughter of James I, King of England and Scotland has been published.

How can governments reach their policy goals in the most effective way? Which manner of financing is the most suitable? Does the spirit of our times call for new forms of subsidy? What does the future of subsidy law look like?

Have you had a busy week at work? If so, it’s better to take a walk in a natural environment than to go shopping in the city.

A new volume, co-edited by Nadine Akkerman of the Leiden University Centre for the Arts in Society, shows how ladies-in-waiting, by 'creatively manipulating their gender', often played a major role in shaping the political climate of Europe in the early modern period.

The €6.24 million EU-funded research project QSPainRelief has kicked off. The project aims to help patients suffering from chronic pain with novel, personalised combinational treatments and is coordinated by Elizabeth de Lange from the Leiden Academic Center for Drug Research.

Nadine Akkerman recently appeared as a guest on a BBC podcast and the History Extra podcast to discuss her book Spycraft. In these interviews, she delved into the fascinating world of espionage, sharing insights from her research and highlighting key themes from her work.

In Harper’s Magazine, reviewer Dan Piepenbring discusses the latest book by professor Nadine Akkerman and Pete Langman. ‘Spycraft’ showcases how and why messages were ciphered in sixteenth- and seventeenth-century England.

Spycraft, by professor Nadine Akkerman and Pete Langman has been selected by History Today and The Economist as one of 2024’s best books

Ever since Nadine Akkerman, Professor of Early Modern Literature & Culture, came across a woman spy in her research, secret agents have kept cropping up in her work. Now there’s Spycraft, a popular history book exploring the espionage techniques used by early modern spies, which she has co-written with…