2,264 search results for “sociale safety” in the Public website
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Workplace and Community: the social and cultural processes of labour movements
Hari Nugroho explores the role of local dynamics in shaping Indonesian labour movements. By focusing on the micro-level, this research reveals how labour organisation strategies are influenced by individual actors' personal histories, their interactions, and the way in which they respond the local economic…
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Jet Bussemaker: ‘Health care is a social matter, not just a medical one’
Why are we unable to address health-care inequality? This was the topic of the inaugural speech of Professor Jet Bussemaker on Friday 15 February 2019. She analysed why current policy does not suffice when it comes to protecting vulnerable groups and fighting inequality. She proposed an agenda that…
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eLaw publishes self-assessment tool on age assurance for the European Commission
Simone van der Hof, Professor of Law and Digital Technologies at eLaw, and Mohammed Raiz Shaffique, researcher and PhD candidate at eLaw, have published a self-assessment tool on age assurance for the European Commission.
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Kiem project investigates link between violence and other health problems
‘Violence as a Population Health Problem’ is one of 33 interdisciplinary projects that have been launched thanks to a Kiem grant. The project team will analyse a large patient database to identify links between violence and other health problems. ‘Violence can also be an expression of other factors,’…
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PhD defense: Calypso Music, Identity and Social Influence:The Trinidadian Experience
On Tuesday 22 November 2016 at 4.15 PM Clarence Charles will publicly defend his dissertation entitled Calypso Music, Identity and Social Influence:The Trinidadian Experience at the Academiegebouw in Leiden!
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Maria Berghuis in EditieNL about PhD thesis: 'Prison visits are form of social control'
Prisoners who have little or no contact with the outside world are more prone to reoffend. What makes visits so important?
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Jorrit Rijpma legal expert on Schengen for the European Economic and Social Committee
On 20 October 2021 the plenary of the European Economic and Social Committee adopted its opinion on the proposed EU strategy for the Schengen area.
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Citizenship, Migration and Global Transformations
Globalization, migration, technological innovation and climate change pose challenges to citizens in European countries. These challenges test the limits of cross-national and cross-generational solidarities, touching upon the very foundations of governance and society. This research program aims at…
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Agnieszka KazimierczukAfrican Studies Centre
a.h.kazimierczuk@asc.leidenuniv.nl | +31 71 527 2727
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Carlos Felipe Blanco RochaFaculty of Science
c.f.blanco@cml.leidenuniv.nl | +31 71 527 4371
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Mirjam WeverSocial & Behavioural Sciences
m.c.m.wever@fsw.leidenuniv.nl | +31 71 527 2727
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Bureaucracy and fragmented social care system mean people do not receive the help they need
In his PhD research in the field of public administration, Mark Reijnders looked at why people do not receive the help they need. They lose their way in the labyrinthine support system or become bogged down in bureaucracy. In public administration this is known as non-take-up of social care. PhD defence…
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Valuing archaeology
Past, Present and Future of Nubian Communities in Sudan
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Tanja AhlinSocial & Behavioural Sciences
t.ahlin@fsw.leidenuniv.nl | 071 5272727
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Dynastischer Nachwuchs als Hoffnungsträger und Argument in der Frühen Neuzeit
This volume sheds light on the role played by progeny in maintaining dynasties in early modern royal courts as well as the horizontal and vertical interplay between the actors. It attempts to break through the narrative of older research that saw dynasties as a series of male rulers. Instead, these…
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Fine Mechanical Department
What is the Fine Mechanical Department?
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Crafting networks in early farming societies
Tracing the residues of Neolithic activities through the study of stone artefacts
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Incentive-Based Physical Activity Programs for Cardiovascular Disease Patients
Promoting sustained physical activity through tailored incentive-based interventions for diverse cardiovascular disease patient groups.
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Final project of the course Social and Ecological Activism in the Visual Arts (minor CSSC)
On 14 December 2022, students of the course Social and Ecological Activism in the Visual Arts (as part of the Creative Strategies for a Society in Change minor) presented and performed their final collective project at BAK, basis voor actuele kunst, Utrecht: the Water Cultures Institute group role-playing…
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15 million awarded for research into misinformation among youth
Developmental psychologist Ili Ma has been awarded an ERC grant to investigate misinformation among teenagers, aiming to bolster their resilience against its potentially severe consequences.
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‘Jongeren die in hun jeugd zijn mishandeld, kunnen ook later in hun leven gevoeliger zijn voor boze signalen van anderen’
Bullying, abuse or a difficult divorce: many young people struggle with mental health problems after traumatic experiences. But why do some suffer much more than others? This is the question that Hannah Dorsman is exploring within the THRIVE project.
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A document classifier for medicinal chemistry publications trained on the ChEMBL corpus
Source: J Cheminform, Volume 6, Issue 1 (2014)
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Quality-driven multi-objective optimization of software architecture design: method, tool, and application
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich
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Kinetics for drug discovery – The first step towards an improved drug discovery paradigm
Supervisor: Indira Nederpelt
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Executive Board
The Executive Board is responsible for the management and administration of the entire University.
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Why Leiden University
n an increasingly complex and security-challenged society, the CSM programme, Governance of Violence, provides you with the theoretical and practical skills to understand the issues underlying security challenges and develop solutions for crisis and security management.
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Why Leiden University?
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Why Leiden University
In an increasingly complex and security-challenged society, the CSM programme, Governance of crisis, provides you with the theoretical and practical skills to understand the issues underlying security challenges and develop solutions for crisis and security management.
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NimbleAI
NimbleAI aims at solutions for ultra-energy efficient and secure neuromorphic sensing and processing at the edge.
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Interested in sustainable innovation and data?
Are you curious about how science and technology contribute to a sustainable and innovative future? At Leiden University, you’ll explore the world of data, natural laws and living systems. From mathematics to artificial intelligence, from climate challenges to high-tech innovation: you’ll learn to analyse…
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Cheminformatics: Analyzing small-molecule activity data
While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.
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Clavis Aurea? Structure-enabled approaches of identifying and optimizing GPCR ligands
Promotores: A.P. IJzerman, H.W.T. van Vlijmen
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Overview
The Division of BioTherapeutics at the Leiden Academic Centre for Drug Research (LACDR) is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Exploring big data approaches in the context of early stage clinical
Als gevolg van de grote technologische vooruitgang in de gezondheidszorg worden in toenemende mate gegevens verzameld tijdens de uitvoering van klinische onderzoeken.
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Host community compensation
Can the offering of host community compensation help to prevent or solve siting controversies, and if so, why and under which conditions?
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Drug discovery and development
New or improved treatments for chronic and acute illness.
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Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation
Source: PLoS ONE, Volume 10, Issue 3 (2015)
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors
Promotor: A.P. IJzerman
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Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines
Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
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Kv 11.1 (hERG)-induced cardiotoxicity: a molecular insight from a binding kinetics study of prototypical Kv 11.1 (hERG) inhibitors
Source: Br. J. Pharmacol., Volume 172, Issue 3, pp. 940-55 (2015)
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Organisation
Organisation of the Leiden Institute of Physics.
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Alternative delivery of a thermostable inactivated polio vaccine
In the near future oral polio vaccine (OPV) will be replaced by inactivated polio vaccine (IPV) as part of the eradication program of polio. For that reason, there is a need for substantial amount of safe and more affordable IPV for low-income countries. Bioneedles, which are biodegradable mini-implants,…
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)
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Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and
Source: Mol Psychiatry (2015)
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Vision
The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.
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A blessing in disguise?! Discretion in the context of EU decision-making, national transposition and legitimacy regarding EU directives
This dissertation looks into the role of discretion granted by EU directives (Article 288 Treaty on Functioning of the European Union) in legislative decision-making and national transposition processes of these directives.
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Editorial: Sanity and Resilience in Times of Corona
This editorial to RHCPP discusses how COVID-19 can be seen as a 'creeping crisis' according to the authors of its lead article (Boin et al, 2020) and how resilience may depend on the real heroes behind the scenes of response to disaster and adversity.
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…