A next, general pharmacological problem to be tackled is how drug-target binding kinetics in vivo, affects target occupancy as an important indicator of the time-course of drug effects.

How can the importance of the image in late medieval spirituality be understood in the context of the love mysticism inspired by the imagery of the Song of Songs?

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

Uniting an international consortium of scholars, the Skandapurāṇa Project comprises a team of researchers working in fields across the Humanities. We are creating a critical edition of a foundational work of purāṇic literature and, in doing so, tracing the dynamics of a textual tradition to better understand…

LRead about how our students and staff are getting involved in making our university greener.

The Leiden Leadership Programme (LLP) employs experts in the field of leadership. They equip LLP students with the necessary leadership knowledge, insights and skills to increase their social impact.

Prof. Elizabeth de Lange is concerned with the allocation of resources for the conduct of science towards the goal of best serving the public interest. Also, while she underscores that there is still the need for using animals in drug research, she is concerned about this use, and advocates the use…

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.

This research cluster explores processes of cultural creation, reception and transformation within a wide range of societal contexts from the early Middle Ages until c. 1800.

LUCIS is directed by Nathal Dessing, who is advised by a steering committee.

At LIACS, we recognize the growing need for advanced technical support in research projects and lab education. Increasing student numbers, more and more advanced hardware and infrastructure, new demands around data safety and management, and the complexity of core computer science courses necessitate…

The research project examines the site-specific event within the field of installation art and choreographic practices.

The 20th Biennial International Conference on Baroque Music will be hosted by the Haute École de Musique de Genève-Neuchâtel at its Geneva campus from Wednesday 28 June 2023 to Sunday 2 July 2023 inclusive.

Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…

Religion, Philosophy, and the Pre-modern World

Indigenous Latin American artifacts have attracted the interest of Europeans since the earliest moment of contact between Europeans and the Indigenous peoples of the Americas. The ERC-funded BECACO project uses an innovative multidisciplinary framework to investigate the provenance of ethnographic and…

Dr Nadine Akkerman, lecturer in Early Modern Literature and postdoctoral researcher in Leiden, has written a new book to accompany the exhibition on Elizabeth Stuart and Amalia von Solms at the Historical Museum of The Hague. ‘They were like goddesses, constantly trying to upstage one another,’ says…

A Leiden literary scholar, paintings of the Winter King and Queen and a string of pearls brought together by an exhibition in the Hague. Dr Nadine Akkerman: ‘The Winter Queen was a highly political person who used every means – including pearls - to showcase her royal lineage.’

Innovative Approaches by Junior Archaeological Researchers

‘Seated behind her desk, she initiated and influenced embassies, conventions, ambassadorial meetings, sieges, and skirmishes that had kept a war-torn early modern Europe in its grip.’ This is how Nadine Akkerman, researcher as the Leiden Institute for Cultural Disciplines and author of The Correspondence…

The organisations and people who implement government policy face many different types of change. Academics from Leiden University research how they deal with these and advise them on how best to meet the needs and wishes of society.

This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB

A new volume, co-edited by Nadine Akkerman of the Leiden University Centre for the Arts in Society, shows how ladies-in-waiting, by 'creatively manipulating their gender', often played a major role in shaping the political climate of Europe in the early modern period.

Sonorous phenomena are always on the verge of becoming something else. As it unfolds, sound constitutes spaces, mediates presence, articulates time. Furthermore, it may prompt emotions, generate awareness, organise patterns of behaviour or trigger a sense of belonging. As sound becomes audible, it is…

Meet the scientists within the LED3 community

Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…

As of 1 March 2018, Elizabeth (Liesbeth) de Lange has been appointed as Professor of Predictive pharmacology at the Leiden Academic Centre for Drug Research (LACDR). She is head of the research group Predictive Pharmacology and mainly aims at developing mathematical models that can predict the effect…

Coming four years after part II, and totalling more than one thousand pages, the long awaited first part of the Correspondence of Elizabeth Stuart (1596–1662), daughter of James I, King of England and Scotland has been published.

For twenty years, the Art History study programme had its own journal, the highly successful Decorum, which was written and edited by students. When the last editor left, the magazine ceased publication. Now, more than 20 years later, it’s time for a new Art History journal.

Nadine Akkerman has deciphered the correspondence of Elizabeth Stuart, Queen of Bohemia, and studied 17th-century spies. Her fascinating historiographies have now been recognised with membership of the Young Academy.