Partly thanks to Roy de Winter, ship design and engineering company C-Job Naval Architects now develops optimal ships in a short time. The master's student Computer Science from Leiden developed the CEGO algorithm, which eliminates the classic design cycle and makes people in the maritime optimization…

On June 2nd Roy de Winter has won the G. Rosenberg Research Award from the Leiden Institute of Advanced Computer Science (LIACS). De Winter was presented with the award during the celebration of the LIACS' 25th anniversary. The new award is intended for promising PhD students at LIACS.

Promotores: T.H.W. Bäck, Y. Tan, Co-promotor: M.T.M. Emmerich

In the next decades, thousands of wind turbines will be added to the North Sea. Environmental scientist Chen Li identified the most beneficial areas for their construction, focusing on material use, carbon footprint, and environmental impact. His paper was published in Environmental Science & Techno…

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

PhD defence

The theme of the Opening of the Academy Year on 4 September was sustainability and how the university could take the lead as a change agent. How is it going about this and what else can it do? There was also room for a critical note.

Andrew de la Haije is Director of the Dutch branch of Xebia Consultancy Services, an internationally operating consultancy agency that coaches companies through digital transformation. He followed the executive master’s programme in Cyber Security and graduated with distinction.

With the advent of multicore processors and data centers, computer hardware has become increasingly parallel, allowing one to run multiple pieces of software at the same time on different machines. Coordination of these pieces is best expressed in a coordination language as an explicit interaction protocol…

The focus of the Antiviral Pharmacology group led by Anne-Grete Märtson is optimizing antiviral therapy for different viral infections by conducting clinical trials and using innovative computational and dynamic laboratory methodologies.

In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…

What is the optimal investment policy according to which a firm adapts its capacity in a competitive market?

The KNVI (Koninklijke Nederlandse Vereniging van Informatieprofessionals) awarded Thesis Prizes for Informatics and Information Science

With the use of big data, Leiden University is aiming to develop a system that sends automatic alerts when certain Industrial parts are starting to wear out. Researchers of the the Leiden Institute of Advanced Computer Science (LIACS) are developing a predictive maintenance platform together with, among…

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.

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The drug discovery pipeline is used to describe the stages in drug discovery. The earliest stage concerns with the identification of potential targets and molecules ('hits') that can modulate their function, while more advanced stages are about developing these hits into viable experimental drugs and…

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Algorithms solve problems. But which algorithm is best suited to which problem? During his doctoral research, Diederick Vermetten developed methods to figure this out. And that is important for the entire field.

The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…

This thesis introduces the concept of

This is a yearly event where we move in one week from the physics of light through the composition of the microscope, fluorescence microscopy and end up with some image analysis All the lectures are backed by practicals to really put your obtained knowledge into practice

The quest for Trustworthy AI is high on both the political and the research agenda, and it actually constitutes TAILOR’s first research objective (H1) of developing the foundations for Trustworthy AI. It is concerned with designing and developing AI systems that incorporate the safeguards that make…

Having a chronic somatic condition can result in a variety of impairments in patients’ daily lives, including not only physical complaints such as pain, itch, and fatigue, but also problems of negative mood and impairments in social relationships. Next to disease characteristics, individual difference…

The Second Chance project aims to promote recovery and re-integration of entrepreneurs who have recently undergone bankruptcy.

Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

Supervisor: Lizi Xia

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

Inspired by natural photosynthesis, perovskite-based photoelectrochemical (PEC) systems are being developed for artificial photosynthesis, aiming to enhance solar-to-hydrogen conversion for green energy.

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

This thesis addresses the challenge of sustainable urban development by analyzing the interplay between green and grey infrastructure to optimize resource use and ecosystem services.

IoT technology poses serval opportunities to supply chains. This thesis employs grey correlation and forecasting models, system dynamics, agent-based modeling, and ex-ante LCA to investigate and quantify the opportunities and risks of IoT-enabled sustainable supply chain operations from both industrial…

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Currently, Navigation Lab Leiden works on three main themes: navigation ability, spatial abilities, novel techniques in neuropsychology.

Children with autism spectrum disorder experience serious challenges in social functioning, which threatens their development in many areas of functioning.

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Promotor: R. Gill, Co-promotor: P. Massart

Timely, adequate and optimal treatment of infectious diseases is essential for the survival of patients with bacterial infections (Surviving Sepsis campaign).