304 search results for “neurodegenerative disease” in the Student website
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Adapting to salinity: Dutch mosquitos do take it with a grain of salt
Dutch mosquitos are more resilient to saltwater than previously thought. Environmental scientist Sam Boerlijst discovered this during his PhD research at the Hortus botanicus. This knowledge is crucial for understanding how mosquito-borne disease transmission might change in the future.
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Scouring the brain for causes of psychiatric illnesses
What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’
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Major Leiden symposium on TB bacteria
More than 1.3 million people worldwide die of tuberculosis (TB) each year, making research on its prevention and control essential. Researchers from various disciplines in Leiden are studying TB. A symposium on 24 March will highlight different activities in the hope of boosting nationwide collabora…
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LUMC participates in pioneering type 1 diabetes research
The promising early results of an international study have shown that insulin-producing cells grown from stem cells can cure the disease. The new Cure One LUMC research centre aims to accelerate this breakthrough.
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ERC grant for Sebastian Pomplun to precisely influence gene expression
In order to stop a whole range of diseases or disorders at their source, you would have to be able to switch certain genes on or off. Sebastian Pomplun wants to develop substances that can do this very precisely. For example, he wants to disrupt cancer processes and make cells produce an important missing…
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Healthy soil for a healthy gut
How does the soil we grow our vegetables in, affects the health of our gut? And does a healthy soil gives crops a better quality and taste? These are some of the questions Soil ecologist Emilia Hannula and a big consortium will work on. With an NWO-KIC grant of 1.8 million, CML, IBL, FGGA, the LUMC,…
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From Covid student to biotech entrepreneur: Violette Defourt is working on rapid STI diagnostics
Violette Defourt came to Leiden for her master’s just before Covid hit. Four years later, she is leading her own biotech company, which aims to radically speed up diagnostics.
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‘To truly understand the brain, we must understand the chemistry’
How do fats and enzymes in the brain contribute to multiple sclerosis? In his PhD research, Daan van der Vliet combined chemistry and neuroscience to gain new insights into how brain disorders develop.
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Funding for four Leiden studies in the fight against arthritis
Four researchers from Leiden University will receive funding from arthritis foundation ReumaNederland over the next five years. This should facilitate long-term research into arthritis.
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Chemistry as the key to medical innovation
Is it a coincidence that three chemists from the same department have each independently received a ZonMw grant? 'No,' the researchers agree in unison. 'The role of chemistry in medical biology is becoming increasingly important, and we’ve worked hard to make this happen.'
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Gilles van WezelFaculty of Science
g.wezel@biology.leidenuniv.nl | 071 5274310
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Mini organs-on-chips: an alternative to drug testing on animals
Mini organs-on-chips allow us to study how diseases develop and how drugs work. Although the technology is not new, it is becoming increasingly advanced. PhD candidate Bart Kramer hopes it will eliminate animal testing in the future.
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LUMC professor Maria Yazdanbakhsh receives Spinoza Prize
Leiden professor of Cellular Immunology of Parasitic Infections Maria Yazdanbakhsh receives the prestigious NWO Spinoza Prize this year. This, in many ways, border-crossing scientist contributes with her research to more effective vaccines against parasitic infections and better medication for inflammatory…
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Master’s students Brechtje de Jong and Ilse de Weert win KNMP Studentenprijs 2024
Brechtje de Jong, a Bio-Pharmaceutical Sciences master’s student, and Ilse de Weert, a Pharmacy student, have won the KNMP Studentenprijs 2024. They received the award for their outstanding academic performance and research internships.
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Healthcare and the Dutch East India Company: Two centuries of arrogance and challenges
The Dutch East India Company (VOC) took healthcare seriously, albeit mainly for business reasons. Former GP Ton Zwaard’s PhD research reveals that although healthcare in Asia was well organised, the VOC faced persistent problems for two centuries.
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Video series: The value of collaboration with Indonesia
Researchers from Leiden and Indonesia work together on a range of projects on topics such as disappearing languages and cultures, the role of Islam, circular economy, biodiversity and medicine. They also work on projects to improve legal education and make Dutch sources and Indonesian heritage accessible…
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UMCs join forces to increase pandemic preparedness
Four university medical centres, including the LUMC, are joining forces to increase pandemic preparedness in the Netherlands.
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Ilze Bot appointed professor of Cardiovascular Pharmacology
Dr Ilze Bot (LACDR) has been appointed professor of Cardiovascular Pharmacology with effect from 1 March. A recognition of her work as a scientist. 'This allows me to continue and expand my line of research within the LACDR and Leiden University.'
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With 30 million dollars, this consortium aims to tackle tuberculosis
Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…
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Hermen OverkleeftFaculty of Science
h.s.overkleeft@lic.leidenuniv.nl | 071 5275037
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Alireza Mashaghi TabariFaculty of Science
a.mashaghi.tabari@lacdr.leidenuniv.nl | 071 5274425
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Faculty of Humanities joins 'Hidden Disabilities Sunflower'
A hidden disability can make studying a considerable challenge, partly because of the disability itself, but also because others may not realise that extra support is justified. To overcome this problem, the Faculty of Humanities is introducing the Hidden Disabilities Sunflower.
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Dental remains shed light on drug use in 19th century Dutch village
Archaeologist Bjørn Peare Barthold suspected farmers in a doctorless 19th century Dutch village may have been self-medicating to manage pain and disease. By examining the skeletons' dental calculus this hypothesis could be tested. Science Magazine interviewed him about this new technique.
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Leiden-developed drug candidate ready for final clinical trial phase
Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.
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LIBC Publieksdag 2025: hoopvolle inzichten in hersenonderzoek
From historical understandings to new treatments: during the Public Day of the Leiden Institute for Brain & Cognition, curious visitors learned how rapidly research into brain disorders is evolving. ‘I found the neurosurgery and the research on organoids on chips particularly fascinating.’
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Quality of life is sometimes more important to the elderly than a cure
Geriatrics needs to radically change. This is what Simon Mooijaart will say in his inaugural lecture.
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‘A few nerves before lectures show that my work matters’
Giving an incorrect answer as a student in a packed lecture hall can be nerve-wracking. But with Pharmacology teacher Rob van Wijk, you don’t need to worry about that. ‘He creates a comfortable and safe atmosphere,’ his students say. They have nominated him for the Leiden Science Teacher Award.
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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Looking at the person beyond the blood clot
How can we improve the treatment of thrombosis, reduce the disease’s impact and spend less money while we’re at it? This is what Erik Klok, Professor of Internal Medicine and an internist, is researching. He will discuss it in depth in his inaugural lecture on 10 March.
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A computational tool that will transform bacterial genome analysis
Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.
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A good pedometer encourages physical activity - but not for everyone
eHealth can improve our lifestyle without the involvement of a healthcare provider. Talia Cohen Rodrigues investigated the possibilities for people with cardiovascular diseases. ‘People with a low socioeconomic status may be more difficult to reach with eHealth.’ She will defend her doctoral thesis…
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Carrot or stick: which is better motivation to exercise more?
Free cinema tickets or a step tracker paid for by your health insurance. Some insurers offer rewards to promote healthy behaviour. But does the threat of losing something like a deposit work better? And what do patients think? This is what PhD candidate David de Buisonjé researched.
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Documentary film alumna Visual Ethnography on show at Pakhuis de Zwijger
Wilke Geurds graduated from the Visual Ethnography master's programme last year with her intimate and vulnerable documentary 'F*ck Endo. More than just menstrual pain.'.
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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Young researchers looking for partnerships in Indonesia
A number of young researchers recently took part in a knowledge mission to Indonesia, aiming to build a lasting relationship with the country. How did they find the trip, what did they do, and how are they creating new connections with scientists in Indonesia?
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Not everyone has health goals top of mind
Preventing or delaying disease often requires lifestyle changes, which turns out to be difficult. Valentijn Visch and Sandra van Dijk are researching how to help people change their behaviour.
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Research projects launched into biodiversity in food and horticulture production
Two Leiden research projects that focus on increasing the biodiversity of Dutch production systems for food and ornamental horticulture have started thanks to funding from the Dutch Research Council's KIC research programme.
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New easy-to-use tuberculosis vaccine patch in development
Researchers from Leiden have developed a promising TB vaccine that users can self-administer via a special patch. This could be beneficial for countries with limited health services, says PhD candidate Malene Neustrup.
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Explosive expansion of invasive marsh frogs
Exotic marsh frogs from distant lands are colonising the south-east of the Netherlands. This has been demonstrated by biology students from our faculty. Although the amphibians thrive in our little country, they are harmful to native biodiversity.
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Veni grants for 22 researchers from Leiden University
An impressive 22 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).
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Hanneke Hulst discusses blind spots and the importance of collaboration
Hanneke Hulst explaines how she is trying to bridge the gap between science and health care. ‘For a neuroscientist to actually contribute to solutions for patients, you have to work across disciplines.’
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Two young researchers win Krijn Rietveld Award for innovative research on blood donation and colorectal cancer
One used 3D cell models to study colorectal cancer, while the other used machine learning for more efficient blood donation. For these achievements, Marieke Vinkenoog and Simon Christian Hansmann were awarded the Krijn Rietveld Memorial Innovation Award on Tuesday 2 September.
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‘Ultimately, the goal is to develop antibiotics for tuberculosis with a lower risk of resistance’
Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…
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In conversation with the head of the rodent facility
Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…
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Subsidy for development of tools for rheumatic diagnosis
Digital diagnostic tools should improve the diagnostic process of patients with musculoskeletal complaints, so that they can receive the right treatment more quickly.
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How to hijack natural destruction in cells: ‘We need to understand it through and through’
Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…
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Obesity and medication: when does bodyweight matter?
How can we best treat infectious diseases in people with obesity? Hospital pharmacist and PhD researcher Koen van Rhee studied how obesity affects blood levels of two commonly used medicines. He also developed a method for pharmaceutical companies to test new drugs on this patient group.
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Arteriosclerosis and drug discovery: two young researchers win Krijn Rietveld Award for innovative research
One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.
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Dutch Cancer Society allocates funds to a mathematician: for treating Ewing sarcoma with the help of an app
If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…
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Sabine van der Asdonk wins Gratama Science Prize 2021
For her research into complex family problems, an assistant professor in Forensic Family and Youth Care Studies Sabine van der Asdonk has won the Gratama Science Prize 2021, a prize for talented young researchers from the universities of Leiden and Groningen. The jury praised Van der Asdonk’s excellent…