We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.

The ambition of the Metabolomics and Analytics Centre led by Thomas Hankemeier is to develop innovative analytical strategies for metabolomics-driven health monitoring and systems biology studies. Understanding the intricate balance between health, disease and adaptation to challenges relies on the…

Why do certain incidents of serious violence end lethally whereas others do not? What role do personal characteristics of offenders and victims play and how do immediate situational factors influence outcomes?

Dissociation is a common symptom in borderline personality disorder and is associated with an increased risk of suicidality and self-harm. Dialectical behaviour therapist Anne Krause-Utz has written a book for clinicians, researchers and students who want to better understand and recognise the pheno…

The research of this PhD project can be subdivided into two main disease areas: migraine and stroke. For both we will be investigating how artificial intelligence (AI) and machine learning (ML) techniques can be used to study these afflictions, their (early) detection, and their potential treatment.

Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.

How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?

How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?

The Dutch police must stop storing personal data indefinitely. This was decided by the Council of State following several publications by investigative journalism platform ‘Follow the Money’ (FTM). Bart Schermer, Professor of Law and Digital Technology, assisted in the investigation.

In the Netherlands it is now possible to visit non-essential shops if you make an appointment beforehand. But when you book an appointment you have to provide a lot of personal data. Are shops allowed to ask you for all this data and what happens to it?

GoodBrother aims to increase the awareness of the ethical, legal, and privacy issues associated with audio- and video-based monitoring and to propose privacy-aware working solutions for assisted living.

Drug-related homicide (DRH) has the potential to act as a valuable indicator of wider drug-related crime. Yet DRH remains a knowledge gap within this broader field of study.

In Dutch magazine Elsevier, Marieke Liem explains the issues with using the term ‘troubled person‘ in reports on homocide.

Have you always wanted to use your own coffee mug at the university coffee machines but it was never accepted? We have good news for you!

Governments are increasingly facilitating the roll-out of so-called “smart meters”, a technology for measuring energy consumption that are able to transmit and receive data using a form of electronic communication. However, implementation has been slow or even stalled.

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

Liposomes hold great promise for peptide-based personalized cancer vaccination, especially when administered intradermally. However, current liposome preparation methods are very time consuming (resulting in long development times per formulation), whereas personalized cancer vaccination requires very…

The person who cried out at Dam Square on Remembrance Day in 2010. For Michiel van der Wolf this marked the rise of a new phenomenon: that of ‘confused people’. Because since that Remembrance Day, the number of reports of ‘confused people’ in the Netherlands has increased rapidly in the statistics.…

A 24 person classroom on the ground floor of PJ Vethgebouw. Rolling, flexible furniture and 5+ writable surfaces supports small groupwork. Furniture is interlocking, supporting multiple arrangments. Features a smartboard TV monitor. Bookable through ZRS.

There are not many classes in which students can talk about their fears, self-critique, or their own happiness. In the Bachelor Honours Class ‘Personal Flourishing and Happiness’, this is exactly the plan.

The Pavement Plants Citizen Science Project invites citizens to monitor plant species growing around their homes, neighborhoods, or towns. The goal is to collaboratively monitor urban flora, measuring and revealing the species richness and biodiversity of the urban ecosystem. We believe this will lead…

Here you will find an overview of the Spaces for Active Teaching and Learning already implemented at Leiden University and LUMC. These rooms vary in size, location, material affordances, and technological affordances, and thus vary in the forms of pedagogy they best support. You can use this site as…

‘Raising awareness of the disorder is crucial since borderline personality disorder (BPD) still faces considerable stigma ’, says Anne Krause-Utz (Clinical Psychology) . Together with an international team of excellent scientists, Krause-Utz provides an update of current knowledge about this disorder,…

We investigate water quality and want to understand the effects of human interference on aquatic biodiversity.

Living labs make it possible for citizens to participate in research for sustainable development of their environment. This way citizens, together with scientists and stakeholders, create local conditions for food production, healthy environment, and biodiversity.

Globally and regionally, biodiversity is declining and there are shifts in species’ occurrences and functional traits.

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

In this thesis I describe the results of Pulsed Interleaved Excitation and Fluorescence (Cross) Correlation Spectroscopy (PIE-F(C)CS) combined with single-pair Förster Resonance Energy Transfer (spFRET) used to study dynamics in single nucleosomes, which depends on subtle differences in the length of…

Key publications of the Antiviral Pharmacology group.

The Honours College Law (HC Law) is soon going to look very different. What does the HC Law currently do, and what’s going to change? Why should you apply for it? To answer these questions, we spoke to Maartje van der Woude, Designated Professor at the HC Law. She’s designing the new programme in collaboration…

At the Faculty of Science, forty per cent of the employees are of a non-Dutch nationality. Amongst PhDs that is even sixty per cent. How are they doing in a time of working at home in a different culture, when travelling is not possible? Astronomer Yamila Miguel is the first in this series to tell her…

Are all murderers calculating psychopaths with an obscene predilection for bloody chainsaws? Yes, if Hollywood is to be believed, but in the real world they are generally everyday people with problematic backgrounds. Professor of Violence and Interventions Marieke Liem therefore calls for the demythologisation…

On Thursday 16 November 2017, Lalin Kovudhikulrungsri will defend her doctoral thesis entitled ‘The Right to Travel by Air of Persons with Disabilities’. The defence will commence at 11.15 hrs at the Academy Building of Leiden University, Rapenburg 73. The supervisors are Professor P.M.J. Mendes de…