Archaeometric analysis of glazed pottery assemblages from the Early Byzantine to the Early Modern periods in the Aegean.

PURPOSE: In the present study we investigated the root-cause of an interference signal (100-200 nm) of sugar-containing solutions in dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA) and its consequences for the analysis of particles in biopharmaceutical drug products.

Promotor: Prof.dr. J.W.M. Frenken

With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…

As society becomes increasingly diverse, public organisations are being challenged to adapt their services to ensure that everyone feels heard and seen. 'Inclusive leadership is essential in this process,' says Dr Tanachia Ashikali. It calls for openness to different perspectives, active dialogue, and…

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

Our group operates at the cross-roads of different disciplines: molecular and cellular microbiology, biochemistry, structural biology and biophysics. The group harbors expertise in a multitude of molecular and cellular approaches including:

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

Leiden University Medical Center (LUMC), Leiden University and Philips are jointly receiving over 2 million euros from NWO to set up an artificial intelligence (AI) lab. The aim of this lab is to accelerate and improve MRI scans with AI. This is great for patients, and it helps make MRI more accessi…

Researchers from Leiden, in cooperation with Philips, have won a challenge in which international research groups dedicate themselves to accelerating MRI scans with the help of artificial intelligence (AI). They developed an algorithm with which it is possible to use eight times less data than normal…

Een samenwerking tussen het Leids Universitair Medische Centrum (LUMC), de Universiteit Leiden en Philips ontvangt financiering van wetenschapsfinancier NWO om MRI-scans te versnellen. Deze drie partijen vormen samen een van de 17 AI-labs die onder de naam ROBUST voor een periode van 10 jaar NWO-steun…

Promotor: J.W.M. Frenken Co-Promotores: I.M.N. Groot; L.B.F. Juurlink

Both Leon Jacobse and Thom Hersbach from Marc Koper's research group obtained their PhDs cum laude. They both investigated changes on the surface of a platinum electrode. Jacobse studied this at a positive voltage, Hersbach at a negative voltage. Platinum has the potential to convert renewable energy…

Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

This thesis describes a study from both a theoreticaL and an experimental point of view.

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

A consortium of researchers from the Leiden Institute of Physics (LION), the Institute of Biology Leiden (IBL), and the Leiden Institute of Chemistry (LIC) received a FOM program grant to develop a novel way of studying individual proteins inside a cell using gold nanorods.

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

An X-ray scanner, some small metal balls, and a newly developed algorithm. That is all you need to make a 3D model that enables you to look inside art objects without dismantling them. Thanks to the research of Francien Bossema (Centrum Wiskunde & Informatica and Leiden Institute of Advanced Computer…

A tenacious postdoc researcher persuaded Professor Marc Koper to research the oxygen reduction reaction. In Koper's eyes, there was little of interest there. But they promptly discovered a whole new way to improve fuel cells on hydrogen and oxygen. Their article appeared in Nature Catalysis on 07 Ju…

The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.

Numerous beads and pendants of amber, jet and bone have been found in Dutch Neolithic and Bronze Age context, both in settlements and in graves. Because ornaments are personal items, they are closely linked with people’s identity.

Physicist Daniël Geelen has developed a new microscope that uses low-energy electrons. Those are less harmful to biological and organic materials. Geelen defends his PhD thesis on May 31st.

This thesis describes the synthesis, analysis of various tetrazine bearing compounds and use in bioorthogonal chemistry.

The Royal Netherlands Academy of Arts and Sciences (KNAW) selects prominent researchers as members based on their scientific achievements. On September 17th, the KNAW will install 21 new members, including Leiden physicist Michel Orrit.

The thesis explores micromammal fossils from the Afşar section in Anatolia, a crucial locality for understanding the Pliocene epoch and the transition to the Villafranchian Age.

MRFM combines the principles of magnetic resonance and atomic force microscopy.

A seven-metre glass tunnel, filled with running water, and equipped with speakers and cameras. An artificial river for investigating what light and sound pollution do to migrating fish.

The Green algae Chara as model system for intra and inter cellular transport processes.

There are several training oportunities within the cell observatory

The Royal Netherlands Academy of Arts and Sciences (KNAW) selects prominent researchers as members based on their scientific achievements. On September 17th, the KNAW will install 21 new members, including Leiden physicist Michel Orrit and chemist Hermen Overkleeft.

The endophytic microbiota is a community of various microorganisms that reside in plant tissue. These microbes are known to promote plant health and resilience, and their members do not simply exist side by side.

An article by Georgina Kuipers has been published this month in Dutch journal Overheid & Aansprakelijkheid (Government and Accountability). It deals with policy introduced in response to damage caused by the construction of the Amsterdam North/South metro line and its aim to rebuild trust. The title…

The CMCB brings together a diverse range of unique expertise in microbial cell biology. Members of the CMCB investigate both model and non-model organisms, bacteria and archaea, pathogens and non-pathogens.

Lecture

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine. The available expertise extends…

Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…

Do natural soundscapes affect migratory decisions of fishes moving up and down rivers and is this process disturbed by vessel sounds?

Studying surfaces of solid materials: it may not seem relevant to energy consumption, but it is. Marcel Rost studies how platinum electrodes wear out. Those electrodes are a crucial component in the fuel cells of hydrogen-powered cars. ‘We need to make the switch from fossil fuel energy to hydrogen.…

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.