941 search results for “that immune response” in the Public website
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A comparative study of COVID-19 responses in South Korea and Japan: political nexus triad and policy responses
This study aims to examine how South Korea (hereafter, Korea) and Japan, two neighboring countries in Northeast Asia, have been responding to and mitigating the spread of COVID-19.
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Physiological responses to a social-evaluative situation
How is the development of physiological responses to social evaluation in adolescence affected by other normative developments, such as pubertal, socio-cognitive and psychosocial development? Are social anxiety and public speaking anxiety associated with characteristic patterns of stress responses…
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Culturally responsive teaching in Dutch multicultural secondary schools
In this dissertation, Dutch secondary school teachers’ attitudes, knowledge, noticing skills and reasoned practices regarding culturally responsive teaching in a multicultural classroom context, were examined.
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In war crimes, commanders do not have legal immunity
In her capacity as a lawyer and expert in International Humanitarian Law and Human Rights, Professor Helen Duffy is filing a lawsuit against the Dutch State. Leiden University’s weekly newspaper Mare reports that through her role, Duffy is assisting a Palestinian Dutchman whose family was killed in…
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Establishing State Responsibility in the Absence of Effective Government
On 16 June 2020, Andrea Varga defended her thesis 'Establishing State Responsibility in the Absence of Effective Government'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. F. Baetens (University of Oslo).
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Disentangling drought-responsive traits with focus on Arabidopsis
In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…
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Corporate responsibility in global supply chains?
For many years, human rights have been considered a playing field in which states were the most important actors. In the present day society, this has changed as a consequence of globalization and the rise of multinational enterprises (MNEs). Protection of fundamental labor rights in global supply chains…
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Mechanical Response of Foams: Elasticity, Plasticity, and Rearrangements
Promotor: M.L. van Hecke
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Unraveling replication stress responses
PhD defence
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Towards responsible and resilient mineral supply chains, with case studies on cobalt, antimony, and zinc
To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.
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Culturally responsive teaching in Dutch multicultural secondary schools
Unraveling culturally responsive attitudes, noticing skills, knowledge and reasoned practices of expert teachers.
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Painting and Response in Sixteenth-Century Venice
Subproject of
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Jin YanFaculty of Social and Behavioural Sciences
j.yan@fsw.leidenuniv.nl | 071 5272727
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Adaptive responses to environmental changes in Lake Victoria cichlids
Promotor: Prof.dr. M.K. Richardson, Co-Promotor: F. Witte
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Too big to fool: moral hazard, bailouts, and corporate responsibility
On the 14th December 2016, Steven L. Schwarcz, Stanley A. Star Professor of Law and Business at Duke University School of Law gave the thirteenth Hazelhoff Guest Lecture. Professor Schwarcz questioned the often-heard assumption that systemically important financial institutions engage in excessive…
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ZonMw - Stimulating academic gatekeeper engagement in responsible research assessment
The project “Optimizing the responsible researcher” (see below) has enriched the knowledge base about the shared values of responsible biomedical research and the various ways in which these ideals are (or are not) put into practice.
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A chemical connection that affects your immune system
A group of chemists, that includes Sander van Kasteren and Hermen Overkleeft, has discovered that azides, a certain type of chemical compound, can determine whether or not T cells respond to or ignore a vaccine. Their discovery is set to be published in Angewandte Chemie.
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Bioorthogonal chemistry to unveil antigen processing events
The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.
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transport: translating environmental signals into plant developmental responses
1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…
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Jennifer SchenseFaculteit der Rechtsgeleerdheid
j.m.schense.2@umail.leidenuniv.nl | 071 5278586
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Data use, online consumer needs, business strategies and regulatory response
This project aims to explore and examine the factors that impact upon the efficacy of information disclosure duties pertaining to customer data use in online business.
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Children's Response to Humor in Translated Poetry
On the 12th of December, Alice Ross T. Morta successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Alice on this achievement!
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New dimensions of the cellular response to DNA damage
Thirty years ago, mutations in the BRCA1 gene were first linked to hereditary breast and ovarian cancer, establishing a genetic basis for cancer development.
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Children's Response to Humor in Translated Poetry
My research examines children’s responses to humor in children’s poems translated from English into Filipino.
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Thorbald van Hall delivers inaugural lecture on training the immune system to counterattack escaping tumours
On 10 September 2021, Professor Thorbald van Hall from the Department of Medical Oncology in the Leiden University Medical Center (LUMC) delivered his inaugural lecture ‘Tumour-immune interactions: control, escape and counterattack’. Van Hall used the opportunity to describe how - in a similar way to…
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protection strategies: Ding lab receives 2.4M grant to investigate plant immunity
Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…
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never happen: Genaralized unsafety and prolonged psysiological stress responses
The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.
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Surviving embryogenesis: The extraembryonic serosa protects the insect egg against desiccation and infection
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee
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Organisations in Peacekeeping Operations and Issues of International Responsibility
Can international organisations be held responsible for violations of international law by peacekeepers in a peacekeeping operation?
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A behavioral view on responsibility attribution in multi-level governance
This article provides a behavioral perspective that examines responsibility attribution to the national government (upward) and policy implementers (downward) as a function of performance relative to decision-makers' aspiration levels. The study proposes that perceived accountability increases the propensity…
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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Vividness of Italian Baroque Sculpture between Literary Convention and Response
Subproject of
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Voluntary return and the limits of individual responsibility in the EU Returns Directive
On 10 February 2022, Christian Mommers defended the thesis 'Voluntary return and the limits of individual responsibility in the EU Returns Directive'. The doctoral research was supervised by Prof. P.R. Rodrigues and Prof. P. Boeles.
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Cornelis Hokkec.h.hokke@lumc.nl | 071 5265065
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Gell's theory of art as agency and living presence response
Subproject of
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ZonMw – Optimizing the responsible researcher: towards fair and constructive academic advancement
Researchers are pulled in various, sometimes contradictory directions by the multiplication of performance metrics and new incentives to align with societal needs. Management structures, funding systems, and publication practices are increasingly influenced by pressures to promote only the highest quality…
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European-wide ecosystem responses and their vulnerability to intensive drought
There is accumulating evidence for an increase in severe global drought events. In particular, Europe experienced several severe droughts in 2003, 2015, and 2018 (unprecedented in the past 2,110 years). Such droughts have caused serious and far-reaching impacts on terrestrial ecosystems.
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Search in Response to Negative Performance Feedback: Problem-Definition and Solution-Generation
In order to test theoretical expectations concerning individual decision-makers' search in response to negative performance, Joris van der Voet conceptually disentangles problem-defining and solution-generation as two distinct search objectives.
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Strengthening the EU’s Response Capacity to Health Emergencies: Insights from EU Crisis Management Mechanisms
Despite an increased EU role in the preparedness, monitoring and coordination of health emergencies over the past two decades, Member States’ responses to the first wave of COVID-19 were surprisingly uncoordinated. In light of calls to improve cooperation regarding future health emergencies, this article…
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Multilevel governance and responses to the COVID-19 pandemic: a systematic literature review
In this article, the authors summarise the literature on the effects of multilevel governance on governments’ policy responses to Covid-19.
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Securing Humanitarian Operations: Preparedness and Response to Cyber Crises in Aid Delivery
How do humanitarian organisations adapt cyber incidents to their specific priorities and needs, and how can they adapt strategies of other organisations?
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in crises: a study of collaborative governance between humanitarian response organizations and virtual & technical communities
How do Humanitarian Response Organizations (HROs) and Virtual & Technical Communities (V&TCs) collaboratively govern disaster sensemaking processes, and what challenges shape the effectiveness of these collaborations between 2010 and 2016?
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MoRRI – Monitoring the evolution and benefits of responsible research and innovation
Responsible Research and Innovation (RRI) implies that societal actors (researchers, citizens, policy makers, business, third sector organisations, etc.) work together during the whole research and innovation process in order to better align both the process and its outcomes with the values, needs and…
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The early stress response of jasmonic acid in cell suspension cultures of Catharanthus roseus
In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…
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Visualization of Vitamin A Metabolism
Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.
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MycobacteriumXL: The intracellular fate of pathogenic mycobacteria
How do mycobacteria subvert the defenses of host immune cells?
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research project to develop novel engineering approaches to study cancer immunity
As part of the HTSM2017 funding program, the LACDR division for Systems Biomedicine and Pharmacology received 1.08 million euros for a research project to develop novel engineering approaches to fight cancer.
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Pharmacometabolomics; prediction of system-wide multi-biomarker drug response
The lack of success of new CNS drugs in clinical development is in part due to the complexity of the CNS, unexpected side effects, difficulties for drugs to penetrate the brain, but also by the lack of biomarkers.
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High throughput microscopy for cellular adaptive stress response pathways in drug adversity
High throughput microscopy