This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.

Within the MAC our Enabling Analytical Technology team is working to innovate all steps of analytical workflows. This includes developing novel sample preparation modules, creative sample handling methods, automated workflows, and more. Several projects implement the microfluidic principle of segmented…

The Technology and Operation Management (TOM) group focuses on the operational challenges of adopting new cutting-edge technologies in areas such as artificial intelligence, precision medicine, and high-tech instrumentation.

This programme video is presented in Dutch

This programme video is presented in Dutch

Dendritic cells (DC) play a prominent role in the priming of CD8(+) T cells. Vaccination is a promising treatment to boost tumor-specific CD8(+) T cells which is crucially dependent on adequate delivery of the vaccine to DC.

Cells in our body are constantly performing small tasks, such as repairing wounds. They exert force by changing shape. But how do cells translate their shape into exerting a force in a specific direction? Experimental and theoretical Leiden physicists have now found a clue to answer this question. Cells’…

To what extent are university teachers' individual learning paths influenced by their teaching experience, motivation, and conceptions of teaching and learning through educational technology?

With the resumption of archaeological investigations at Satricum (Borgo LeFerriere, Latium), in 1977, a broad array of themes, methodologies and analytical approaches have been pursued. A common thread is technology, which encompasses all social, economic and cultural aspects of human agency.

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…

The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…

The Algorithms and Software Technology (AST) research programme performs fundamental research in the areas of algorithm design and analysis.

Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…

Law and Digital Technologies (L.L.M.) examines the legislation and governance regarding internet, computers, persuasive technologies and ambient intelligence.

Since September 2001 Leiden University's Media Technology MSc program has educated modern academics, creative nerds, playful programmers, tinkering thinkers, and conceptual cross-disciplinarians. On May 13th, we celebrate!

Leader in law and technology education and research since 1985.

Cyber agent technology and intelligence agencies is a project that is commissioned by Tracks Inspector, a Dutch company that develops innovative software.

Technological advances have an impact on our daily lives. They have also been employed by governments to manage border security, especially at controversial border crossings. Fences, heat sensors, heat cameras, drones and other hi-tech equipment that are currently being tested collectively produce a…

Study information

A Diachronic Perspective on the Aegean

How do you ensure that research is performed, evaluated and managed in a responsible way? This question is also of the utmost important to the University itself. The Centre for Science and Technology Studies (CWTS) studies scientific research and its relationship with technology, innovation and soci…

Cell-based medicinal products (CBMPs) show great promise when it comes to the treatment of genetic disorders. However, there is limited knowledge about CBMP stability during their production, storage, and administration to patients. The main focus of my research is the characterization of CBMPs using…

A very large part of intravenously administered nanoparticles are cleared through the liver. Within the liver, most nanoparticles are thought to be sequestered by macrophages (Kupffer cells). To achieve effective cell-specific targeting of drugs and non-viral gene delivery vectors, improved mechanistic…

This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.

Are you thinking about studying the Advanced LL.M. Law and Digital Technologies? Learn more and watch the videos.

The Centre for Science and Technology Studies (CWTS) is a research institute at Leiden University working on improving how science is practiced and governed and how it serves society.

African oral literatures, new media and technologies: challenges for research and documentation

A more efficient solar panel sounds great. But what if these new panels consume more toxic materials, or their production consumes a lot of energy? Leiden environmental scientists, together with colleagues from the Fraunhofer ISE, address this multifaceted question in a new publication in the prestigious…

This volume is the outcome of collaborative European research among archaeologists, archaeobotanists, ethnographers, historians and agronomists, and frequently used experiments in archaeology.

This volume provides an authoritative, cutting-edge resource on the characteristics of both technological and social change in warfare in the twenty-first century, and the challenges such change presents to international law.

For effective cancer immunotherapy by vaccination, co-delivery of tumour antigens and adjuvants to dendritic cells and subsequent activation of antigen-specific cytotoxic T cells (CTLs) is crucial. In this study, a synthetic long peptide (SLP) harbouring the model CTL epitope SIINFEKL was encapsulated…

This report concerns itself with terrorist technical innovation, particularly with regards to terrorists’ incorporation of emerging technologies into their practices. More specifically, it investigates, through the elaboration of a theoretical learning framework, how terrorist groups can adopt the practices…

Leiden biophysicist Stefan Semrau was granted an NWO Vidi earlier this month. He will use the grant to study the role of electricity in embryonic development and tissue regeneration.

Thread-like bacteria make cells that no longer have a cell wall under the influence of osmotic stress. A remarkable discovery, since the cell wall serves as a protection barrier for bacteria. It could also help to explain how pathogenic bacteria can hide in our body from our immune system. A team of…

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

An examination of academic organization at the forefront of the biotechnology revolution

New technology offers many new possibilities for research, such as on dementia. ‘Organ-on-a-chip’ is a new technology in which small bits of organ are grown out of stem cells on a small plastic plate. A small piece of blood vessel, heart or nerve offers many new possibilities for research, such as…

The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.

Language learners in higher education increasingly conduct out-of-class self-directed learning facilitated by mobile technology. This project aims to explore how university students use mobile technology for their self-directed language learning and investigate factors that influence their self-directed…

How digital technologies affect the way we conceive of the self and its relation to the world, considered through the lens of media art practices.

Explores the relationship between technics and humanity, tracing the emergence of a bio-technical conception of existence in contemporary continental philosophy. Suny Press

The LUMC has become the first institution in the Netherlands to treat a patient with an autoimmune disease using CAR T-cell therapy.

The Case of the Painted Plaster

Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.