847 search results for “text immune responses” in the Public website
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The early stress response of jasmonic acid in cell suspension cultures of Catharanthus roseus
In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…
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Visualization of Vitamin A Metabolism
Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.
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MycobacteriumXL: The intracellular fate of pathogenic mycobacteria
How do mycobacteria subvert the defenses of host immune cells?
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Nees Jan van EckFaculty of Social and Behavioural Sciences
ecknjpvan@cwts.leidenuniv.nl | 071 5276445
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Leiden University outlines approach to responsible collaboration following advice of Committee on Human Rights
Leiden University is announcing its approach to sensitive collaboration with external partners.
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Pharmacometabolomics; prediction of system-wide multi-biomarker drug response
The lack of success of new CNS drugs in clinical development is in part due to the complexity of the CNS, unexpected side effects, difficulties for drugs to penetrate the brain, but also by the lack of biomarkers.
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High throughput microscopy for cellular adaptive stress response pathways in drug adversity
High throughput microscopy
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The Legend of Saint Aūr and the Monastery of Naqlūn: The Copto-Arabic Texts
Clara ten Hacken defended her thesis on 16 December 2015
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from the other mountain: Chinese fan fiction based on English source texts
On Friday 22 November 2024 Ye Jiang successfully defended a doctoral thesis and graduated.
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Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines
Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)
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‘I always thought I was immune to stress, but now I’m not so sure’
Lecturers had a week to move their courses online. An enormous challenge because remote teaching definitely wasn’t commonplace at Leiden University. Suzan Verberne, a lecturer and researcher at LIACS, shares her experiences. ‘I tried to do too much in my first week working from home.’
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Metabolic signatures in nutrition and health: short-term diet response, sexual dimorphism and hormone chronobiology
The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).
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How partisan politics influence government policies in response to ageing populations
Kohei Suzuki is Assistant Professor at Institute of Public Administration. This study carries several important implications for understanding the policy impacts of a graying population and for studies of the welfare state, in general.
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A Priori Truth in the Natural World : A Non-referentialist Response to Benacerraf's Dilemma
The main question addressed in this thesis is how we can best conceive the contrast between a priori and empirical truths.
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Framing conditionality in times of crisis: EU institutional responses to Turkey’s democratic decline (2014–2024)
In this article, Seda Gürkan, Özlem Atikcan and George Christou examine how EU institutions responded to Turkey’s democratic decline between 2014 and 2024, analysing how conditionality was framed and applied by the European Commission, European Parliament and European Council.
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
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Many objective optimization and complex network analysis
This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.
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Margo DonaFaculty of Science
m.a.dona@biology.leidenuniv.nl | 071 5272727
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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CHERRIES - Constructing Healthcare Environments through Responsible Research Innovation and Entrepreneurship Strategies
The project will support Responsible, Research and Innovation (RRI) policy experiments in the healthcare sector in three European territories: in Murcia (ES), Örebro (SE) and the Republic of Cyprus (CY). CHERRIES will engage the territorial stakeholder ecosystems in participatory agenda setting, need…
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interactions to unravel biomarkers for disease progression and treatment response
The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets
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Protease-Responsive Targeted Delivery of Chemotherapeutics Holds Great Promise for the Treatment of Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is the deadliest common cancer, with only 8% of patients surviving for five years. One reason for this poor outcome is that current chemotherapy treatments are highly toxic, often leaving patients too sick to receive treatment or forcing doctors to lower the dose…
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Maria YazdanbakhshFaculty of Medicine
m.yazdanbakhsh@lumc.nl | 071 5265067
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Isabella Brunner -
Paul van den BroekFaculty of Social and Behavioural Sciences
p.vandenbroek@fsw.leidenuniv.nl | 071 5272727
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Lifeng HanFaculty of Science
l.han@liacs.leidenuniv.nl | 071 5272727
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Constructing an ‘emotional community’ in times of crisis: the EU’s response to Russia’s invasion of Ukraine in 2022
Emotions play a key role in EU politics. This article examines how emotions influence the EU’s response to international crises and norm violations.
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Unending Variety: Papyrological Texts and Studies in Honour of Peter van Minnen
The subjects of the texts vary from Demosthenes to the delivery of camels in early Islamic Egypt, and their provenances stretch from the Eastern to the Western Desert, and from the Egyptian Nile valley to Qasr Ibrim in northern Nubia.
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Not just a protein machine: How ribosomes regulate immune response
PhD defence
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Inspirational practices in cultural heritage management: fostering social responsibility
This catalogue is the result of the EU_CUL project (2018-2021), which explores the use of cultural heritage in Europe for fostering academic teaching and social responsibility in higher education.
- Gender Approaches to Cybersecurity: design, defence and response
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Quantitative modelling of the response of earthworms to metals
Promotor: Prof.dr. W.J.G.M. Peijnenburg, Co-promotor: Dr. ing. M.G. Vijver
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Rosema & Louwerse, ‘Response scales in Voting Advice Applications’
Voting Advice Applications represent popular election campaign tools in many countries, enabling voters to discover which party or candidate provides the best match with their political preferences. Political scientists Martin Rosema (University of Twente) and Tom Louwerse (Leiden University) examine…
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Trading Responsibility: navigating national burdens in a globalized world
International trade has played a major role in defining the modern global economy. Trade, however, entangles the environmental pressures of economic sectors, giving the illusion of environmental improvements, while the opposite may be occurring.
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The Bulgarian governments' response to Covid-19
Emerging from the first wave relatively unscarred to an increase in infections. This research analyses the response from the Bulgarian government to Covid-19.
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Andrea BartolucciFaculty of Governance and Global Affairs
a.bartolucci@fgga.leidenuniv.nl | 070 8009506
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Digging in documents: using text mining to access the hidden knowledge in Dutch archaeological excavation reports
The archaeology domain produces large amounts of texts, too much to effectively read or manually search through for research. To alleviate this problem, we created a search system (called AGNES), which combines full text search with entity and geographical search.
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Texts, Voices and Tapes. Mediating Poetry on the Swahili Muslim Coast in the 21st Century
In the Special Issue of Matatu: “Power to the People?” Patronage, Intervention and Transformation in African Performative Artspaper, Annachiara Raia seeks to investigate the manifold relationships between traditional and contemporary, oral and written Swahili poetry, in the utendi and mashairi forms…
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Does feedback targeting text comprehension trigger the use of reading strategies or changes in readers' attitudes? A meta-analysis
Our previous meta-analysis (Swart et al., 2019) had shown that feedback targeting text comprehension given when students perform a reading task positively influences learning from text. So far, differences in the effects of feedback were explained by design features, such as the timing and richness…
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Determining the most appropriate dose metrics for evaluating dose-response relationships of metal-based nanoparticles to Zebrafish embryos
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Environmental Refugees. A human rights-based, security and State responsibility approach
On 7 May 2020, Jolanda van der Vliet defended her thesis 'The International Legal Protection of Environmental Refugees. A human rights-based, security and State responsibility approach'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. J.J.C. Voorhoeve.
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Illuminating Host Defence against Mycobacterial Infection: Interactions with Autophagy and LC3-Associated Phagocytosis
Despite substantial progress in understanding tuberculosis (TB), the eradication of the TB epidemic is still far from reach.
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Figurations animalières à travers les textes et l’image en Europe
Fish climbing trees, storks taking care of their parents… Premodern textual and visual culture presents us with a fabulous bestiary that reveals ingenious and rich reflections on the animal kingdom.
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understanding and provision of an enhanced and robust monitoring system for Responsible Research & Innovation (RRI)
Across Europe, the need for a more dynamic governance and a better societal integration of research and innovation is increasingly appreciated. Internal drivers of change (such as the digitalization of science) and political will to better align with societal needs and concerns are bringing about aspirational…
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Decoding supplier codes of conduct with content and text as data approaches
The growing popularity of corporate self-regulation to address supply-chain issues puts Corporate Social Responsibility and specifically codes of conduct, at the centre of attention. In this article, Jaroslaw Kantorowicz, Sarah Vandenbroucke and Yvonne Erkens analyse supplier codes of conduct of multinational…
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The importance of friendships in reducing brain responses to stress in adolescents exposed to childhood adversity: a pre-registered systematic
Up to 50% of all children and adolescents growing up worldwide are exposed to at least one form of childhood adversity (CA), which is one of the strongest predictors for later-life psychopathology.
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Firefighting robots must be developed responsibly
As robotics advances in the field of emergency response, firefighting robots – or 'firebots' – offer promising improvements in safety and operational efficiency. However, to ensure these technologies truly benefit society, non-technological factors must be considered from the outset.
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Arnout KoornneefFaculty of Social and Behavioural Sciences
a.w.koornneef@fsw.leidenuniv.nl | 071 5271861
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Automated text analysis of policy-related documentation
Political institution (like the Council of the European Union and the European Parliament) generate large bodies of text. These great amounts of text can impossibly be read by a researcher. Contrary to human researchers, computers are able to read thousands of documents a day. In this research project…