Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Engaged, active students who can see the links within their discipline. These are key aims of the University vision on teaching and learning, but how do you achieve them? An interdisciplinary research team led by ICLON has developed an inventive method that helps lecturers do just that.

From 27 to 31 January, a workshop on the regulation of plastic pollution based on scientific evidence will be held at the Lorentz Center in Leiden.

Almost 100 billion tons of CO₂ could be pulled out of the atmosphere by the end of the century. That is, if high-income countries switch to a plant-based diet. The double carbon profit of returning farmland to its natural state would equal about 14 years’ worth of agricultural emissions, researchers…

Americans more often donate funds to a presidential candidate if the campaign is backed by financiers from different, recognised social groups. This is the conclusion of Leiden researcher Vincent Traag in an article in Plos One published on 14 April.

What is the impact of research-based learning on critical thinking competence and academic achievement in undergraduate education? What are underlying factors of research-based learning in the learning environment?

The Journal of European Public Policy has dedicated this year’s Special Issue to the theme of European Union Enlargement and Integration Capacity, on the suggestion of Dr. Antoaneta Dimitrova, senior lecturer at the Institute of Public Administration of Leiden University. Moreover, the Special Issue…

Bioenergy with carbon capture and storage (BECCS) is a promising method for removing carbon dioxide (CO2) from the atmosphere and simultaneously generating energy. Yet this method is controversial, as it may require a great deal of land and water. Researchers at Leiden University have now proposed a…

Leiden University Medical Center (LUMC), as a partner in the reNEW consortium, is once again receiving tens of millions of euros for research into new treatments based on stem cells. The collaboration will receive a total of €150 million to develop new therapies in regenerative medicine.

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

Promotor: M. Ubbink, Co-promotor: G. Siegal

Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

Didactics

Basketry, cordage and textiles made of plant fibers or bark are rarely preserved in the archaeological record. By means of experimental archaeology and microwear analysis, we obtain indirect evidence about this important craft.

As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.

The chemical synthesis of inhibitors and probes targeting endo-glycosidases.

How can we effectively increase biodiversity and climate resilience in Dutch cities from an ecological, societal and governmental perspective?

Promotor: G.A. van der Marel, Co-Promotor: J.D.C. Codée

Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.

In this project, researchers from computer science, law, psychology, and public administration research in practice how artificial intelligence (AI) can be leveraged to make decision-making in the security domain more effective, while also keeping it safe and accountable.