Promotor: M. Franx, Co-Promotor: I.F. Labbé

Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert

Volume II: Plates of Room Contents

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

Source: Eur J Med Chem (2015)

Volume I: Excavation and Material Culture

The central aims of MicroClock project are to describe the B. subtilis circadian clock at molecular and functional levels, and discover the mechanisms of clock-regulated bidirectional signaling between B. subtilis and the model plant Arabidopsis

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

Supervisor: Andrea Martella

The Aging and Immunity group is led by Dr. Amanda Foks. In this group we aim to investigate how aged immune cells contribute to atherosclerosis and identify novel therapeutic targets and strategies to extend health span and inhibit cardiovascular disease.

The research group of Semonti Bhattacharyya at the Leiden Institute of Physics studies quantum transport measurements in Van der Waals heterostructures.

Source: PLoS ONE, Volume 10, Issue 3 (2015)

What did we do over the past year? Well, we played quantum games, helped develop an instrument for the Extremely Large Telescope and started a new bachelor's programme. Oh, yeah, and we officially opened our brand new Gorlaeus Building! Warm up the fingers and get ready to click and scroll through…

Underneath you will find the 12 most important Facebook events that took place at the Faculty of Governance and Global Affairs in the past year, and an overview of our Instagram highlights of 2018.

On Friday evening 17 September, Leiden astronomer Joe Callingham can be seen in a new series on Discovery channel. Killers of the Cosmos is about different deadly dangers lurking in the depths of space. Asteroids, cosmic debris, electromagnetic weapons… The show takes a film-noir approach to these threats,…

The Leiden archaeologist Harold Berghuis was closely involved in archaeological discoveries off the coast of Java. Skull fragments and other fossil remains provide new insights into the world of Homo erectus. The discovery was the subject of numerous news reports.

How can rare and expensive materials be used more efficiently to produce cleaner and cheaper fuel? Under the guidance of Marc Koper, Professor of Catalysis and Surface Chemistry, international teams of scientists have published 3 articles in Nature Communications.

There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

Come to the Night of Discoveries art and science festival on 16 September. Various researchers from the university are speaking at the festival.

In a recent article published on PLOS, Drs. Briana Pobiner and Ryan McRae of the Smithsonian Institution National Museum of Natural History discuss the top 13 discoveries in human evolution in 2023.

A previously unknown document about Rembrandt’s student years in Leiden has been found in the archive of Leiden University. The document, which is being kept at the University Library, proves that Rembrandt studied at Leiden University for longer than has always been assumed.

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

Spycraft, by professor Nadine Akkerman and Pete Langman has been selected by History Today and The Economist as one of 2024’s best books

Promotor: M. Ubbink, Co-promotor: G. Siegal

A full overview of MacBio PhD Theses.

The discovery of new medicines is a tedious and lengthy process. On average, over 10,000 molecules need to be studied for one to become a drug and reach the patient. Part of that process are the very costly clinical trials in humans, and candidate drugs often fail due to side effects or lack of efficacy.…

During the course of drug discovery translational steps are made.

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

Update : March 2020 A.J. Mills

The Austrian Studies Fund supports the Special Chair for Central European Studies, invites visiting professors from Austria and connects with Austria Centres over the world.

Plant Sciences' contribution to the Bioactive Molecules research theme is to identify new plant bioactive molecules, and unravel their mechanisms of action in plant development or health, and the regulatory networks and (bio)synthetic pathways required for their production.

Could an emergent Cinema of Un-Belonging discover forms of narrative time relevant to the long-term, inter-generational fractures caused by forced traumatic dispersion?

Read on these pages all about the history of Leiden University, the oldest university in the Netherlands. The Academia Lugduna Batava was founded in 1575 and its motto is: Libertatis Praesidium ('Bastion of Freedom').

To explore the potential of marine microorganisms as producers of novel antimicrobial agents and as bioprotectants in aqua- and agriculture, using an integrative, ecology-based strategy for bioprospecting.

The Biomedical Metabolomics Facility Leiden (BMFL) is the core metabolomics facility of Leiden University and the Metabolomics and Analytics Centre (MAC). We offer a highly structured environment for advanced MS-based metabolomics studies and build on fully validated, state-of-the-art assays that each…

Rob van Wijk gave an interview on the role of zebrafish in drug discovery and development, published in FIGON’s journal Medicines as a preview of LACDR’s representation at the PhD competition during the Dutch Medicines Days (DMD). The entire interview can be read below.

'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…

In your first year at LUC you gain the basic knowledge and lay the foundation and skills for your specialization in year two and three.

The student weekly diary of Archaeology/Egyptology students, 2022.

What would a university be without its students? In 2025, we will celebrate 450 years of studying with an exhibition showcasing our students from the past centuries. How did they study in the past? And how do they study now? This outdoor exhibition will be on display from 23 April at the Hortus bota…

The student weekly diary of Archaeology/Egyptology students, 2023.

The student weekly diary of Archaeology/Egyptology students, 2020.

The student weekly diary of Archaeology/Egyptology students, 2024.