This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

Science begets technology but technology also begets science. Anne Urai from the Leiden Institute of Psychology is part of an international team team that rolls out a new, user-friendly, plug-and-play AI tool they hope will become an engine of discovery by quantifying the growing volume of recorded…

On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…

Shared, general-purpose labs.

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

How does self-reliance lead to a decrease in collaboration for public goods?

From basic science to real-world interventions

Promotor: Koen Kuijken Co-promotor: Henk Hoekstra

Associate professor at the Natural Products Laboratory, Institute of Biology, Leiden University - the Netherlands

Biological and behavioural measurements of parent-child interactions.

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Measurement of brain activity by external electrodes (EEG).

We aim to unravel the molecular mechanisms involved in the transformation of eukaryotic cells by Agrobacterium.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Promotor: T. H. Oosterkamp

At ACPA, the collaboration between Leiden University and the University of the Arts The Hague, artistry and academia meet at the highest level.

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

Our world is shrinking, or at least our electronic devices are. From PCs to mobile phones: everything is smaller and thinner. The smaller the chip, the better it can conduct electricity and pass on information.

The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…

High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.

Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.

Cognitive psychology is the study of cognitive functions such as attention, memory, consciousness, emotion, language and action control. The goal is to understand the complex relationships between brain, mind and behavior.

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

Cognitive processes of learning with a focus on reading comprehension and the development of mathematical skills.

This thesis investigates reactive interfaces in surface science across three domains: heterogeneous catalysis, environmental nanoplastics, and two-dimensional materials.

The Gorlaeus Building will be constructed in three phases, with the new building due to be completed by 2028.

Research in Bio-Pharmaceutical Sciences consists of 120 European Credit Transfer System (EC) points.

How do individuals make decisions? What determines the quality of group decisions? When and why do people cooperate with others? How does intergroup competition evolve?

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…

Social anxiety and factors determining school success in children. Brain development in relation to cognitive, social and emotional development in adolescence.

The LUC Fund is part of the Leiden University Fund (LUF). The Fund is managed by LUC’s administrative staff and overseen by a Spending Committee consisting of staff and alumni. Together they are responsible for the allocation of available resources, identifying funding opportunities, and developing…

Understanding the formation and preservation of Pleistocene fire traces through laboratory-based experimental research

This study aims to make a practical contribution to a new understanding and use of 3D reconstructions, namely as ‘laboratories’ to test hypotheses and visualize, evaluate and discuss alternative interpretations.

In June-August 2010 large scale excavations were executed on the cemetery belonging to the monastery, an area now termed the Paardenmarkt, by Hollandia Archeologen in cooperation with Leiden University. During the course of nine weeks, the students from the former minor Human Osteoarchaeology excavated…

Leiden University is constructing a new building for the Faculty of Science in three phases, featuring state-of-the-art research and teaching facilities. The second phase was completed in 2024 and includes, among other things, a stunning entrance with a mathematical touch. With this development, the…

To what extent did the street patterns in urban districts influence crime patterns?

In this consortium CWTS (Leiden University) collaborates with two Swedish SMEs: Monocl AB and Recorded Future AB. Monocl AB delivers intuitive analysis software to Life Sciences professionals in support of strategic decisions and improvement of business performance. Recorded Future AB is an organization…

How can sustainable and circular decision-making be integrated into manufacturing operations? How can data from physical simulation models, digital twins and operations be used for sustainability assessment? How can manufacturing decisions affecting sustainability and circularity be integrated into…

Leiden has a strong tradition in theoretical physics, thoroughly linked with experimental disciplines.

On this page the programme and sessions can be found. The programme will be updated regularly.

Research training projects in the MCBIM group - Bachelor and master students of all chemistry related studies are more than welcome to take part in our research activities. We have various research projects, all in one way or another involving transition metal ions. Daily supervision in the laboratory…

Contact the Graduate School of Science Office

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

Development and validation of instruments that can measure different aspects of emotional competence in children with normal and atypical development, and in different cultures

Entry requirements for students with a degree from a Dutch University of Applied Sciences (HBO)