In this study Lilie Roosman describes the effects of prominence and boundary marking on the temporal and melodic structures of two regional languages of Indonesia, viz. Toba Batak, a stress language, and her native language Betawi Malay, a non-stress language.

Lack of money impacts how a person takes financial decisions: now or preferably later. Procrastination and avoidance behaviours in turn have an effect on lack of money, which can result in a sense of loss of control. These are the findings of psychologist Leon Hilbert in his PhD research, although the…

Fear of repayment demands is causing people to forgo benefits and financial support, even when they are eligible. This was one of the finding of Olaf Simonse in his PhD research on financial stress and the non-use of social services. His proposal: 'Let the government take the initiative.'

Misleading graphs, the erosion of democracy and the weakening of bones as a side-effect of medication. Researchers are starting work on these very topical problems, funded by subsidies from the Leiden University Fund awarded on 12 October.

Bones hold a wealth of information about a person’s life, revealing details about where they came from, how old they were when they died and what diseases they may have had. Scientists can use this data to piece together aspects of an individual's life, offering valuable insights that can help address…

In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…

The MicroSOS project is designed to bring together academic and industrial partners with different expertises to address challenges that agriculture is facing due to climate change and invests in the development of microbiome-based solutions towards more sustainable agricultural practices.

This thesis aims to investigate the effect of tripartite interaction between microbial inoculants, the plant, and herbivore insects on the rhizosphere microbiome and volatilome. We investigated the rhizosphere microbiome and volatilome of tomato plants exposed to insect herbivory and/or inoculated with…

Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.

Social resilience and security has never been more important. Over the last 2 years, the COVID-19 pandemic has created a considerable disturbance to our personal and social lives. As a result, the general population reports more stress, loneliness and decreased quality of life. At the same time, there…

Occupational health in the Emergency Department

The aim of our research program is to better understand the etiology and course of mood, anxiety and stress-related disorders, such as depression and posttraumatic stress disorder (PTSD). We investigate both the transdiagnostic mechanisms underlying these disorders and work on improving the treatments…

To make the right clinical decisions or develop effective diagnostic tests and treatments, it is important to understand the underlying mechanisms of a condition or behavior.

The more we learn about a (neuro-)psychological or physical disorder and the related behavioral factors, the better we can not only identify them, but also treat them. It is therefore important that recent insights about (neuro-)psychological problems and related behavioral factors are incorporated…

Our team consists of the following members.

Can excessive worrying be reduced via stimulation of the vagus nerve?

In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.

The Faculty of Medicine

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Supervisor: Xue Yang

Supervisor: Lizi Xia

How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

Psycho-physiological reactions to stress.

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

From basic science to real-world interventions

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

The Resilience Center Leiden investigates how stress impacts the mental health of young people. For that, the team studies a multitude of factors, such as childhood experiences, the social environment, psychological factors, and neurobiological factors. With this multidimensional approach, we aim to…

The research connected to this topic is related to Work and health.

Towards Health and Resilience in Volatile Environments - People differ in how they are impacted by and respond to stressful experiences. Why is that?

You can find some tips here on how to maintain your mental health.

Making public space more sustainable is considered very important in this project. The Humanities Campus will become a pleasant place to spend time, with lots of greenery. Here, people can relax and find coolness on hot summer days.

There are differing opinions about healthcare for transgender young people. Lieke Vrouenraets investigated the ethical dilemmas.

The aim of the REACT Study is to examine whether baseline inflammation, and/or neuro-immune responses to stress in a sample of adolescents with experiences of childhood adversity predicts: the perception of stress, social behaviour and general mental and physical health during and after the COVID-19…

How does stress influence cognitive performance? What is the role of selective attention to threatening information in this effect? Could we prevent stress-induced decline of cognitive performance with pharmacological interventions? Could we use resting state theta/beta ratio as a biomarker for cognitive…

The research connected to this topic is related to E-health.

Animal Sciences’ contributions to the Biodiversity & Evolution research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.

Knowledge of mental distress and resilience factors over the time span from before to after a stressor is important to be able to leverage the most promising resilience factors and promote mental health at the right time. To shed light on this topic, we designed the RESIST Study, in which we assessed…

Begin oktober vond de eerste Psychology Connected van dit nieuwe academische jaar weer plaats. Met de vallende herfstbladeren voelen velen zich ook somberder. Onderzoekers delen hoe je een winterdepressie verzacht, en hoe je als ouder het beste kunt omgaan met de depressieve klachten van je kind.

Work might not always be enjoyable, but what if just a glance at the to-do list brings on a sense of dread? To initiate the conversation about this, the sixth Psychology Connected focused on work pressure and workplace enjoyment, offering tips rooted in positive psychology.

One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…

In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.

Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…

How is the development of physiological responses to social evaluation in adolescence affected by other normative developments, such as pubertal, socio-cognitive and psychosocial development? Are social anxiety and public speaking anxiety associated with characteristic patterns of stress responses…

To study relationships between emotion regulation after negative and traumatic life events and psychopathology. Within this context, another goal is to develop and validate emotion regulation questionnaires.

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.