Promotor: S.M. Verduyn Lunel

‘Violence as a Population Health Problem’ is one of 33 interdisciplinary projects that have been launched thanks to a Kiem grant. The project team will analyse a large patient database to identify links between violence and other health problems. ‘Violence can also be an expression of other factors,’…

The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Cell Systems and Drug Safety, Medicinal Chemistry and Systems Pharmacology and Pharmacy, and the Metabolomics and Analytics Centre.

The interdisciplinary Kiem project ‘Violence as a Population Health Problem’ has resulted in a plan to apply for a large, yet-to-be-decided research grant. The so-called pressure cooker session at the heart of the project proved very effective.

The Biomedical Sciences Master programme in Leiden will help to deepen and broaden your understanding of human health and disease. We provide you with a challenging and flexible programme in a personalized environment.

For more information regarding ongoing research projects, please contact Prof. Miranda van Eck.

For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.

The Faculties of Leiden University have developed several themes for research cooperation between Leiden University and its Indonesian partners.

Early treatment benefits patients who have not fully developed rheumatoid arthritis but are in the preliminary stages of the disease. This is what researchers from the Leiden University Medical Centre (LUMC) have reported in The Lancet. Patients in the pre-arthritis stage who were temporarily prescribed…

Prof. Andrea Evers is a health psychologist who studies the role of behavioural factors in health and disease. As a Medical Delta Professor, she is now affiliated with Leiden University, TU Delft and Erasmus University. In that position, she conducts research at the intersection of various disciplines.…

More than half of the Indonesian population lives in cities. What does this mean for public health? How sustainable are these megacities? This is the subject of the ‘Urban Transitions’ Summer Academy on West Java. This summer course is also the kick-off for a renewed interdisciplinary partnership…

The Dutch Research Council (NWO) is investing 197 million euros in 11 infrastructure projects that will be of great value to science and society. Leiden University and the Leiden University Medical Center (LUMC) are participating in eight of the eleven proposals.

It sounds futuristic, but it is possible: the creation of miniature organs of patients in order to study them and see how diseases develop and can be treated. This is what researchers from the LUMC, Twente University (UT), UMCG, TU Delft and the Hubrecht Institute hope to achieve in the next ten years…

Can small molecule drugs restore the immune system’s ability to fight tuberculosis by boosting autophagy?

Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

Nobody is better qualified to tell you what it is like to work at Leiden University than the employees themselves. Watch the videos and meet your future colleagues. They will be happy to share their experiences with you.

In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.

The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.

Eleven Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant will enable them to develop their research ideas for a period of three years.

With this thesis the PhD-candidate aims to enrich the body of evidence concerning the relation between stress and health, and the mediating role of (un)conscious perseverative cognitions, which is captured in the extended perseverative cognition hypothesis.

Professors Simcha Jong (Leiden University) and Rifat Atun (Harvard University) convened an exploratory seminar to discuss challenges for health systems in realising the potential of precision medicine at Harvard University’s Radcliffe Institute for Advanced Studies in Cambridge, MA on 17 April 2017.

On 15 May, the ambassadors of 11 Latin American and Caribbean countries were shown the highlights of research at Leiden University Faculty of Science. Furthermore, Prince Carlos de Bourbon de Parme awarded prizes to two young academics who conduct research in Latin America.

How do plant defense genes get activated?

A new health programme will reward patients with - or at risk of developing - cardio-vascular diseases for keeping to a healthy lifestyle. A research group including psychologist Andrea Evers has been awarded 2.5 million euros by the Dutch Heart Foundation and the Ministry of Public Health, Welfare…

We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.

Researchers, policymakers and funders have to take more account of the effect of sex and gender in scientific research. This is the view presented in an advice paper published by LERU, the League of European Research Universities. The lead author is Vice-Rector Simone Buitendijk.

Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…

The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We are moreover strongly involved in the Master specialisation of Pharmacy at Leiden University. We work on clinical problems that require further mechanistic understanding and…

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

The objective of the PhD Education and Supervision program is to educate PhD candidates in becoming professionals who are competent to conduct scientific research in the field of the pharmaceutical sciences independently.

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Atherosclerosis, in particular rupture of atherosclerotic plaques, is the underlying cause of most heart attacks or strokes and is the leading cause of death worldwide.

The BENEFIT programme is a public-private ecosystem in a national consortium, aiming to support patients with cardiovascular diseases in their own home setting for a long-term healthy lifestyle.

Promotor: Prof.dr. J. Kuiper, Co-promotor: Saskia C.A. de Jager

Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.

PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.

The Institute of Psychology is committed to play a prominent role in teaching and research at the national and international level.

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

Machine Learning is becoming a more and more substantial technology for industry.

Dr. Jessica Kiefte-de Jong and Dr. Thijs Bosker, both Assistant Professors at LUC, have been awarded by The Leiden University Fund (LUF).