This project aims to develop a portable, real-time intelligent system tailored for speech disorder therapy.

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

Xinrong Ma defended her thesis on 13 February 2018

The project investigates the changing local context of crime dynamics and the responses by selected international organizations and national governments. It places a major emphasis on security management at the trans-national level by investigating intra-regional security cooperation between Latin America,…

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

How do young adults find their way in an increasingly complex society? In Leiden, as part of the GUTS project, we study how brain development and self-regulation play a role in this process.

Using artificial intelligence is more complicated for the government than for companies. Bram Klievink, Professor of Public Administration, aims to identify the problems and find solutions.

In December 2024, the book Redressing Fundamental Rights Violations by the EU: The Promise of the ‘Complete System of Remedies', edited by Melanie Fink, was published fully open access with Cambridge University Press. The EU prides itself on having created a legal system that puts the individual at…

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

This is the first special issue of any organisation studies journal on food labour. Why is this a big deal? In this Introduction, we argue that the field should pay much more attention to the agri-food system and the work that goes into producing, distributing and consuming foodstuff. Food is such an…

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

Analysis of drug adversity

The upscaling of Life Cycle Assessment (LCA) data is recognized as one of the main challenges in the ex-ante LCA of emerging technologies. This challenge arises since industrial-scale system specifications for these technologies are unknown and industrial data is lacking.

Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years

Promotor: S.M. Verduyn Lunel

Lodewijk Petram, author of the book 'The World's First Stock Exchange', discussed the rise of the Amsterdam stock exchange in the 17th century in the ninth Hazelhoff Guest Lecture.

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.

Grasseni's contribution to this special feature on food cultures, food systems, and agriculture in Europe builds upon her ongoing project Food citizens? Collective food procurement in European cities: solidarity and diversity, skills and scale.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Valentina Carraro explores the relationship between overlapping UN human rights institutions, specifically the treaty bodies and the Universal Periodic Review (UPR)

The lack of success of new CNS drugs in clinical development is in part due to the complexity of the CNS, unexpected side effects, difficulties for drugs to penetrate the brain, but also by the lack of biomarkers.

When we are in a conversation, how do we know exactly when to respond, and how do we manage to respond so swiftly, yet without interrupting our interlocutors? Can speech melody – in particular utterance final “boundary tones” – help us determine who will speak next, or are these cues too late in the…

Promotor: Prof.dr. M. Danhof

Think tanks have proliferated in most Western democracies over the past three decades and are often considered to be increasingly important actors in public policy. Still, their precise contribution to public policy remains contested.

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.

Across Europe, the need for a more dynamic governance and a better societal integration of research and innovation is increasingly appreciated. Internal drivers of change (such as the digitalization of science) and political will to better align with societal needs and concerns are bringing about aspirational…

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Promotor: Prof.dr. L.J. Slikkerveer

It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.

Every time we pay for something, our money moves through global technical systems that connect the world economy. These systems are convenient, but they also expose users to Western sanctions, prompting countries like Russia to look for alternative financial infrastructure.

The potential of liposomal cancer vaccines

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.

HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.