Drawing on the analogical lessons of the Great War, this article uses applied history to analyze how the four parallels discerned can help us make sense of contemporary Sino-American rivalry

Archives were a common target during the Second World War, and hundreds suffered damages. Among these archival losses, the losses to medieval manuscript collections stand out.

This week 'Dutch Post-war Fiction Film through a Lens of Psychoanalysis' by Peter Verstraten was published by Amsterdam University Press, the sequel to Humor and Irony in Dutch Post-war Fiction Film from 2016. Each chapter in his 482-page new study begins with a title of Fons Rademakers who made films…

This paper written by Alexandre Afonso, Assistant Professor and Researcher at Leiden University, argues that gender norms and the political strength of the left were important structuring factors regarding why European countries choose migrant labour to expand their labour force in the decades that…

This book presents an introductory survey of the major themes, thinkers and texts, philosophical genres and profound insights of the Chinese philosophical tradition. Its coverage ranges from the foundational history of Chinese thought in the 6th–5th centuries BCE up to the present day.

This interdisciplinary study focuses on (trans)national ethnic and popular networks, combining historical-ethnographic and computational methods to understand the ‘workings’ of networked conflict interfering in the increasingly violent conflict in the Sahel (Africa) and beyond. The project focuses on…

Histories Connected: Seminar

Research conducted at Leiden has established that guts-on-chips respond in the same way to aspirin as real human organs do. This is a sign that these model organs are good predictors of the effect of medical drugs on the human body. Publication in Nature Communications on 15 August.

Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…

Cancer research generates massive amounts of data, but traditional tools often fail to fully harness their potential. How can we unlock this data to provide better treatments for cancer patients? PhD candidate Marina Gorostiola González explored this by using advanced data analysis techniques to guide…

The impact of a ceasefire shifts over the course of a conflict, as conflict party leaders learn more about each other’s military and political aspirations and adapt their use of ceasefires accordingly. That’s the key message of the dissertation of Valerie Sticher, PhD-candidate at the Faculty of Governance…

Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.

From studying molecules in the blood of corona patients to developing a new concept for vaccines. The Leiden Academic Centre for Drug Research (LACDR) has transformed many ongoing projects into Covid research projects. Hubertus Irth, scientific director of LACDR, talks about the role of his institute…

The impact of war extends beyond destroyed buildings and torn families. In bilingual Ukraine, the ongoing war with Russia is a major driver for increasingly discarding the Russian language. What does this mean for the position of Russian in Ukraine?

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.

Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…

In health care, artificial intelligence is quite normal: it is used, for example, as an aid in making diagnoses. However, artificial intelligence is not yet used as much in drug development. A new prestigious partnership is therefore going to investigate how artificial intelligence can contribute to…

On Wednesday 9 March, a Faculty meeting about the war in Ukraine was held for staff and students in the Lorentz Lecture Hall. By the time the meeting started at 17.00 hrs, the 220 available seats in the lecture hall had been filled mainly by large numbers of students.

PhD defence

Actin and microtubules form cellular cytoskeletal network, which mediates cell shape, motility and proliferation and are key targets for cancer therapy. Changes in cytoskeletal organization correlate with proliferative capacity and invasiveness of cancer cells. These changes expectedly lead to altered…

On Friday, November 17, 2017, Assistant Professor Jens Iverson provided the Keynote for the annual symposium by the Minnesota Journal of International Law: Jus Post Bellum: Justice After the War.

Professor Ian Lilley, the Faculty of Archaeology’s Willem Willems Chair in Archaeological Heritage, was invited by Her Excellency Mrs. Marion Derckx, Ambassador of the Kingdom of the Netherlands in Australia, to present the 2022 commemoration speech for Netherlands Memorial Day on May 4th at the Netherlands-Australia…

The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…

Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.

Conceptualizing ceasefires as bargaining instruments challenges established ideas about the processes that lead up to conflict settlement, and about war re-emergence, with important implications for our understanding of war and peace.

The Leiden Academic Centre for Drug Research (LACDR) has received a €750,000 grant from ZonMw for QPharmNL. This is a continuing education programme that trains professionals in computational techniques in pharmacology for innovative drug development.

Adopting a largely chronological approach, Gerrits links the historiography of post-war Europe and the major theoretical approaches to nationalism with analysis of key historical developments and events.

The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.

In an essay published in three prominent European newspapers, Professor Luuk van Middelaar takes a close look at Europe’s role in the Russian invasion of Ukraine. ‘Europe shows plenty of political energy, but what is still lacking is strategic cool-headedness, in facing a nuclear power.’

This thesis tackles the difficulty of predicting the liver’s clinical response to novel therapies, a challenge arising from interspecies differences and limitations of existing in vitro models.

Tensions ran high last week after China published a list on Wednesday of $50 billion in American products that would be hit by tariffs; a direct response to the United States' decision to implement $50 billion of tariffs on Chinese products. Could this be the start of a new trade war? And if so, what…

Endocannabinoids - the body's own marijuana - are promising departure points for drug research. Professor of Molecular Physiology Mario van der Stelt examines whether inhibiting their production can be a way to fight inflammatory brain disease and to combat obesity. Inaugural lecture 19 October.

International pharmaceuticals company Grünenthal is to open an innovation hub on the Leiden Bio Science Park. The hub will make it easier for scientists and drug developers to work together.

Promotor: B. van de Water

In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.

Starting January 18, the online exhibition Images of the Indonesian War of Independence, 1945-1949 can be viewed via the UBL website. The exhibition is the result of a collaboration between the Royal Netherlands Institute of Southeast Asian and Caribbean Studies (KITLV) and Leiden University Libraries…

According to Russian propaganda Ukrainians are Nazis and people from the West are Satanists. Egbert Fortuin thinks we should take this propaganda seriously.

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

Promotor: M. Ubbink, Co-promotor: G. Siegal

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

When Russia invaded Ukraine at the end of February, normal life there came to a halt. To ensure that affected students and researchers can continue their studies and work, professor Ellen Rutten (UvA) and assistant professor Dorine Schellens (Leiden) set up an international mentor network.

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

Simon Willmetts provides evidence for systematic policy of direct collussion between the TIme Inc. media empire and U.S. Central Intelligence Agency.

Claire Vergerio, political scientist at Leiden University, has been awarded a VENI grant by Dutch research organisation NWO. This will allow her to conduct an in-depth analysis of the legal rights and duties of non-state actors involved in warfare. The aim is to tackle some persistent blindspots in…

Stories of resistance in the Second World War are widely covered in Dutch historiography: Hannie Schaft, Erik Hazelhoff Roelfzema, and Professor Cleveringa are some of the best known. But these accounts largely focus on the Dutch domestic perspective. On the other side of the world, a complex colonial…