1,514 search results for “brain functions and dysfunction” in the Public website
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Criminal law and criminal procedure (LL.M.)
Criminal Law and Criminology is is a specialisation of the master’s programme Rechtsgeleerdheid (Law) at the renowned Leiden Law School of Leiden University.
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After graduation
Psychology graduates acquire skills useful in a variety of jobs. Whether helping people with mental disorders, researching the brain or deciding who should be hired at a company, psychologists can do it.
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Rebel with a cause: The effects of leadership encouragement and psychological safety on professionals' prosocial rulebreaking behaviour
This article examines leadership encouragement and psychological safety as antecedents of prosocial rule-breaking (PSRB) behaviour.
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Intercellular Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients
Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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Psychosomatic Imagery. Photographic Reflections on Mental Disorders
Introduces a novel trope of photographic images dealing with states of mental disorders; focuses on photographs that visualize disturbed corporeal and mental perceptions of the world and connects medium-specific characteristics of photography to concepts from mental disorder studies.
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Highly Accurate Simulations and Benchmarking of Molecule-Surface Reactions
Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.
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Pressure on function of checks and balances in Parliament
Polls conducted by I&O research point to a political landslide. What's in store for the Netherlands? The polls show that the new party of MP Pieter Omtzigt is well-positioned for the upcoming election, with an expected 31 seats, but only 3 for the Christian Democratic Alliance (CDA) party. It is obvious…
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Carlijn BergwerffFaculty of Social and Behavioural Sciences
c.e.bergwerff@fsw.leidenuniv.nl | 071 5272727
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Serge RomboutsFaculty of Social and Behavioural Sciences
romboutssarb@fsw.leidenuniv.nl | 071 5269111
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ScaleHDR - Scale-dependent Heterogeneity-Diversity Relationships
How does environmental heterogeneity shape biodiversity across spatial and temporal scales?
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Provincial council election results prove democracy is functioning well
Voters sent a clear signal in the recent Dutch provincial council elections with the 'monster' victory for the Farmer-Citizen Movement (BoerBurgerBeweging, BBB). This sign of ‘social resistance’ has consequences for the policy on nitrogen emissions, according to Geerten Boogaard, Professor of Local…
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Is lack of sleep bad for study performance?
The Netherlands Association for Sleep-Wake Research is studying this issue. Lead researcher Kristiaan van der Heijden, Leiden psychologist and sleep specialist, invites students to take part in the study.
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Monitoring drought and salinity stress in agriculture by remote sensing for a sustainable future
Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…
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Computational electrocatalysis
This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.
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Exhibition on the many functions of academic portraits
A portrait can inspire, intimidate or reassure the viewer. Leiden University has many portraits of professors and students, from the foundation of the University to the present day. What purpose do these portraits serve? The 'Facing Inspiration' exhibition in the Oude UB is about this question.
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Metaphor in Machine Translation: Reactions, Responses, Repercussions
This project investigates which metaphors are problematic in machine translation, when, why, and for whom.
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Supramolecular and Biomaterials Chemistry
Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…
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Updated MRI scanner ready for use
The updated MRI scanner at the Leiden Institute for Brain and Cognition (LIBC) will become operational on 29 September. The new version is faster and better than the current model.
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and
Source: Mol Psychiatry (2015)
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Peacekeeping in South Lebanon: Credibility and Local Cooperation
In this book, Vanessa Newby provides the first detailed examination of credibility’s essential place in peacekeeping.
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The activation mechanisms of G protein-coupled receptors: the case of the adenosine A2B and HCA2/3 receptors
Promotor: A.P. IJzerman
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A new method to reconstruct the structure from crystal images
Promotor: J.P. Abrahams, Co-promotor: T. Grüne
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Group benefits from genomic instability: a tale of antibiotic warriors in Streptomyces
Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.
- Institute of Urban Environment
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Urbanism in the Roman frontier provinces Germania Superior, Raetia and Noricum
What was the nature of the urban network in the Roman provinces of Germania Superior, Raetia and Noricum and how stood this in relation with economic and social developments?
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Topics
In our research and education, we focus on the following topics:
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Efficient constraint multi-objective optimization with applications in ship design
Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Museums, Heritage and Collections
Museums are powerful and influential institutions in their ability to shape knowledge and contribute to our identity. What we preserve and how we present our collections and heritage is closely connected to our identity and culture. In the multidisciplinary Museums, Heritage and Collections, you'll…
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Modern and Contemporary Studies (1800−Present)
This research cluster centres on regional, national, and global intersections between a variety of artistic and cultural expressions and their role in society from 1800 onwards.
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Split Jacobians and Lower Bounds on Heights
This thesis deals with properties of Jacobians of genus two curves that cover elliptic curves.
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Surface Temperature and the Dynamics of H2 on Cu(111)
Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…
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Peter van Bodegomp.m.van.bodegom@cml.leidenuniv.nl | 071 5277486
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Two new functions for anthropologist Erik Bähre
Erik Bähre has been elected to the board of the Society of Economic Anthropology of the American Anthropology Association. On top of this he has joined the scientific advisory board of the NIAS-Lorentz Program.
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The distribution of stellar mass in galaxy clusters over cosmic time
Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: Dr. H.Hoekstra
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Eveline Crone wins Dr Hendrik Muller prize
Eveline Crone, professor of neurocognitive developmental psychology at Leiden University, has been awarded the Dr Hendrik Muller Prize for Behavioural and Social Sciences by KNAW.
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Training children in self-control
What is the effect of training children to exercise self-control? Niko Steinbeis has been awarded a major European subsidy to find the answer to this question. The innovative aspects of this research are the target group, an individual approach to the training and examining the child brain the scann…
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Charge transport properties of Ru-complex molecules: the influence of humidity
I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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Lipid chain length reduction correlates with the skin barrier function in atopic eczema patients and inflammation plays a role in the altered
Source: Journal of Investigative Dermatology, Volume 135, pp. S59-S59 (2015)
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Eveline Crone new ERC Vice-President
Eveline Crone, Professor of Neurocognitive Development Psychology at Leiden University, has been elected as the new Vice President of the European Research Council (ERC). She will be in charge of ERC activities in the domain of Social Sciences and Humanities.
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Programme
The programme of the 3rd International Workshop on Klinefelter Syndrome, Trisomy X, and XYY. International Workshop theme: 'A life-course perspective'
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years of International Studies: ‘During lectures I sometimes felt my brain was exploding with all the new insights.’
The bachelor's programme in International Studies is celebrating its tenth anniversary. Ko Voskuilen was among the very first batch of students to follow the study, and Sophia Healy graduated this summer. How do they look back on their time at the university?
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Predicting dementia
In the future, physicians may be able to identify dementia much earlier than they can today because a computer algorithm will be able to predict from brain scans how our memory is going to develop.
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Density functional theory is an accurate predictor for variation with geometry of barriers for reactions on metals
A semi-empirical version of the specific reaction parameter approach to density functional theory (SRP-DFT) has been remarkably successful at predicting dissociative chemisorption probability vs. incidence energy curves for reactions on metal surfaces. New quantum Monte Carlo (QMC) calculations on the…
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Developmental and Educational Psychology Lab
What is the relation between brain development and social and cognitive development across childhood, adolescence and adulthood?