kiem grant: Investigating the anti-inflammatory potential of the PRG4 protein in preventing and alleviating rheumatoid arthritis

Promotor: E.F.A. Deprettere, Co-Promotor: A.C.J. Kienhuis

Professor of Clinical Pharmacology Adam Cohen from Leiden University received the prestigious Dr. Saal van Zwanenberg Honorary Prize on 12 November. The prize honours a scientist who has distinguished themselves in the field of research that has directly or indirectly led to the development of new medicines…

Four university medical centres, including the LUMC, are joining forces to increase pandemic preparedness in the Netherlands.

This project is opening up the possibility of systematically studying research teams from a broad perspective, by developing specific bibliometric methodologies able to identify active collaborative research teams in Africa. Based on the extensive experience of CWTS and CREST, this project represents…

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

This study aims to answer two main research questions: (1) What are the main predictors of work ability in employees with migraine? (2) Can we optimise work ability in employees with migraine using a web-based intervention focused on these relevant predictors?

'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…

Not taking into account the saturation of drug targets can lead to wrong conclusions about the duration of a drug's action. This is what former PhD candidate Wilbert de Witte writes together with the Leiden professors of pharmacology Meindert Danhof, Piet van der Graaf, and Liesbeth de Lange in Nature…

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.

Healthcare Information Systems (HIS) are essential for modern healthcare delivery, yet their development faces significant challenges including heterogeneous data formats, regulatory compliance, and the growing demand for AI-driven decision support.

The Department of Child Law collaborated on a study on missing children in the European Union for the European Commission. The outcomes of the study aim to help to improve the mechanisms involved when children are missing in EU Member States.

Galaxies in the Universe are distributed along the intricate framework of the Cosmic Web. Groups and clusters of galaxies comprise the densest regions in this network, and therefore, are excellent cosmic laboratories to study different aspects of galaxy evolution in extreme environments.

SBB research focuses on the complex operational, organisational dynamics of technology-intensive sectors.

Computers are capable of making incredibly accurate predictions on the basis of machine learning. In other words, these computers can learn without intervention once they have been pre-programmed by humans. At LIACS, we explore and push the borders of what a revolutionary new generation of algorithms…

Leiden chemists have proposed a new model for enzymatic reactions, in which the flexibility of the substrate is much more important than previously thought. Their results are paradigm-shifting and could have major implications for drug research and enzyme engineering. Publication in Angewandte Chemi…

PhDArts alumnus Joost Grootens’ book 'Blind Maps and Blue Dots: The Blurring of the Producer-User Divide in the Production of Visual Information’ has been selected in the competition the Best Dutch Book Designs 2021.

In the light of today’s major changes and challenges, the congress on November 22 will focus on Redesigning the Designer while also taking some of the examples of more-than-human knowledge experimented with within Neuhaus as a starting point for a new network.

How to deal with the most challenging design question of your life: what do I want to be when I grow up? The ‘Designing Your Life’ method teaches students how to craft their own future. The project will start next academic year, thanks to a Comenius grant. ‘Everyone interested should be able to borrow…

Sharing knowledge based on research within organisations presents a challenging task. How can this be done effectively? What steps should be taken to ensure that knowledge obtained from research is shared and applied in the organisation's daily practice? On 8 May, the Leiden Leadership Centre (LLC)…

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

Getting motivation, courage and tools to find a job that will help you tackle the climate crisis: it is at the heart of the course ‘Designing Your Career as a Climate Changemaker’. With their final presentations, the students conclude this climate-specific skills module within the Designing Your Life…

Phage therapy is a novel yet unmatured therapeutic approach in the face of the crisis of antimicrobial resistance (AMR). Dr. Tingjie Guo received a grant from the Elise Mathilde Fund and the LUF to develop innovative phage-antibiotic combination treatment strategy for combating AMR.

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.

Promotor: A. Kros

NWO awarded a grant for novel research on Complex and Distributed Cyber-Physical Systems (CPS). The grant will fund a four-year research project in which they hope to devise a method to explore and find optimal designs for CPS. Todor Stefanov, Associate Professor at the Leiden Institute of Advanced…

Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…

Yisheng Development is to design the entrance area to the Leiden Bio Science Park. Leiden University and the municipality of Leiden selected this Amstelveen-based project developer on the basis of their sustainable design for a vibrant campus. The design provides a combination of residential, working…

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

Getting personal

The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Knowledge on how to adjust a drug dose in special patient populations such as (prematurely born) neonates or children, obese individuals or critically-ill patients, is not only crucial for novel compounds, but also for existing drugs which are often used in an off-label manner in these special patient…

What is involved in setting up and carrying out clinical research? To give researchers a helping hand, LUMC Campus The Hague has brought together tips and tricks in the new massive open online course (MOOC) Population Health: Study Design.

Research lines within the Pharmacy group:

Fascinated by science since high school, Alireza Mashaghi Tabari is driven to explore new ways of thinking in medicine. With a strong academic network, he educates students and gives public lectures. For his research at LACDR, he won the C.J. Kok Public Award 2018, making him the Faculty of Science's…

On Friday 12 March 2021, the (Dutch) website www.codevoorkinderrechten.nl was launched. This code for children’s rights has been created to help those involved in the development and design of digital services to develop these services with the interests of children in mind.

The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Cell Systems and Drug Safety, Medicinal Chemistry and Systems Pharmacology and Pharmacy, and the Metabolomics and Analytics Centre.

The chain that supplies patients with new medicines consists of various complex links: from fundamental research to clinical tests and production. This entire chain is represented in Leiden. Leiden University, the Leiden University Medical Center (LUMC), and the companies on the Leiden Bio Science Park…