812 search results for “immunity infection and tolerance” in the Public website
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Bioprinting human tissues for drug testing
Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza Mashaghi lab at the Leiden Academic Centre for Drug Research. The lab has recently been equipped with two state-of-the-art bioprinters: BioX and LumenX+.…
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Interreligious Encounter in a West African City: A Study of Multiple Religious Belonging and Identity Among the Yorùbá of Ogbómòsó, Nigeria
How has interreligious encounter in Ogbómòsó created multiple religious belongings and identities among individuals and groups?
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Dignity and respect, diversity and inclusion
The Faculty of Social and Behavioural Sciences is committed to being a safe, comfortable, and equitable space for both staff and students: a place where a diversity of people feel valued and welcome, where there is room for a diversity of perspectives.
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Normativity and its sources: Agency, interaction and conflict in a globalizing world
Are there general principles or values that should govern our actions as moral agents and/or as political subjects?
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Can large carnivores like tigers survive in multiple use forests? A study in the buffer zone of Panna Tiger Reserve, India.
Which factors (human-dimension and carnivore related) shape human tolerance of large carnivore and large carnivore survival in multiple use forests?
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A Dutch Republican Baroque. Theatricality, Dramatization, Moment and Event
In the logic and aesthetics of a republican baroque the existing world is the result of a moment in which for a split second two or more realities are equally real and after which only a singular one becomes actualized.
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NExt ApplicationS of Quantum Computing (NEASQC)
The NEASQC project brings together academic experts and industrial end-users to investigate and develop a new breed of Quantum-enabled applications that can take advantage of NISQ (Noise Intermediate-Scale Quantum) systems in the near future. NEASQC is use-case driven, addressing practical problems…
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Beyond Prometheus: Pursuing the origins of fire production among early humans
When do fire making tools appear in prehistory, and how might the use of these tools manifest in the archaeological record?
- Book Chapters
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Institute for the Interdisciplinary Study of the Law
Most people know what law is. But what it should be or where it comes from is what interests the researchers from the Institute for the Interdisciplinary Study of the Law. Key to their approach are topics that go right to the heart of philosophy of law. What is a state? What are the limitations of…
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Respiratory-chain enzymes
Many metalloenzymes that are key to bioenergetics are membrane enzymes, with canonical examples the complexes I, II, III and IV in the mitochondrial inner membrane. To study these enzymes in a native-like lipid membrane environment, we aim to develop novel bioelectrochemical techniques.
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Veni grants for 25 Leiden researchers
From molecular ping-pong to cassava in the Amazon, and from extraterrestrial life to special antibodies. Twenty-five researchers from Leiden University have been awarded a Veni grant from the NWO. A grant of up to 250,000 euros will give them the opportunity to further elaborate their own ideas over…
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Ruling: temporary coffeeshop licences are allowed
Coffeeshop licences may be issued temporarily and reissued after this period has expired. This follows from a ruling by the Administrative Jurisdiction Division of the Council of State in the appeal lodged by the mayor of Roermond municipality against the Court's April 2021 ruling.
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American presidents and their special relationship with Leiden
President John Quincy Adams studied in Leiden. His father, John, who was also president, also stayed here and received a lot of support from professor and publisher Johan Luzac. And how are presidents Bush and Obama linked to Leiden?
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Cellular therapy promising treatment for arteriosclerosis
Vanessa Frodermann, a PhD student at the Biopharmaceutical department of the Leiden Academic Centre for Drug Research, has discovered that arteriosclerosis could be inhibited by cellular therapy. Arteriosclerosis is one of the leading causes of the development of cardiovascular disease. Her PhD defence…
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ERC grant to improve post-vaccination protection in low-income countries
Maria Yazdanbakhsh, Professor of Parasitology at the Leiden University Medical Centre (LUMC), has been awarded an ERC Advanced Grant of 2.5 million euros. She will investigate why people in Africa and Southeast Asia respond less to certain vaccines than Europeans. Her goal is to find a solution for…
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Are bacteriophages the new antibiotics?
Bacteriophages, viruses that infect bacteria, may be used as an alternative treatment option when antibiotics fail. Leiden researchers have studied the structure and function of a novel bacteriophage that could be used to treat one of the WHO bacterial strains of concern where new treatments are urgently…
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Research lines
Current research at the Skin Barrier and Vaccination group.
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Exploring host-immune-microbial interactions during intestinal schistosomiasis
PhD defence
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Cancer vaccine packaged in minute particles
Leiden researchers have carried out successful tests using a new method of packaging a cancer vaccine in nano-particles. The new vaccine has induced a strong immune reaction in mice. The researchers believe that this method can make an important contribution to the treatment of cancer. Their findings…
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Erik van Kampen publishes in the Journal of Leukocyte Biology: The effects of poor eating habits persist even after diet
New research published in the Journal of Leukocyte Biology suggests that these changes to the behavior of the immune system are persistent and can continue even after diet is improvedAlmost everyone knows that improving your eating habits will most likely improve your health. What most people may not…
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Therapeutic vaccine boosts survival rate in cervical cancer patients
A therapeutic vaccine against HPV-16 (type 16 human papillomavirus) improves the survival rate in cervical cancer patients. A new study by ISA Pharmaceuticals B.V. (a Leiden-based biotechnology company) and the Leiden University Medical Center (LUMC) shows that this vaccine produces a more robust response…
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Tiny, pain-free vaccinations: microneedles and nanoparticles
If it’s up to PhD student Guangsheng Du, patients don’t need to worry about big needles anymore. At the Leiden Academic Center for Drug Research (LACDR), he studied the use of microneedles and nanoparticles as a new vaccination system. ‘I want to create a more patient-friendly delivery method.’ He defends…
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Key publications
Key publications of the Quantitative Pharmacology group
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Awards
These honors and distinctions were given to work that was done within the Media Technology program by both students and staff.
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Research
Through our research, we work towards a fundamental understanding of the world and people around us. We use that knowledge to make the world a safe, healthy, sustainable, prosperous and just place.
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Health and disease
Bone research provides plenty of detailed data about the health of a person or a group. This data is not only used to reconstruct the past but also to fight disease today.
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Less is more: reduced mycelial heterogeneity for improved production of enzymes and antibiotics
How can cell wall engineering approaches be used to improve streptomycetes for industry to make new antibiotics?
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Institute of Biology
Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’
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Erik Danen part of NWO Perspectief grant for organ-on-chip
A consortium of research groups, including that of LACDR professor Erik Danen, will use an NWO Perspective grant of nearly five million euros to build a universal standard for organ-on-chip models. They aim to stimulate the application of these chips in the biomedical and pharmaceutical industry. Danen…
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Bosscha Medal for Professor Taniawati Supali
At the opening of the LDE-BRIN Academy on 31 October, the Bosscha Medal was awarded to Professor Taniawati Supali from the Department of Parasitology at the University of Indonesia. She receives the medal for her outstanding contribution to science and her working style, which is characterised by collaboration,…
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User-friendly test brings global elimination of leprosy closer
Researchers from the Leiden University Medical Center (LUMC) are working on the first diagnostic test for leprosy that can be used outside a laboratory. This will not only reliably diagnose leprosy, but also be cheap and easy to use. Leprosy mainly occurs in low-income countries. A double challenge…
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Major European subsidy for Health psychologist Andrea Evers
Andrea Evers is the new Professor of the brand-new unit of Health, Medical and Neuropsychology. She's getting off to a flying start in Leiden with a consolidator grant of the European Research Council (ERC). Her ambition? 'To work together with other disciplines; that way we can arrive at new insigh…
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ERC Consolidator Grants for four Leiden researchers
The European Research Council has awarded ERC Consolidator Grants to four researchers from Leiden. These grants of up to 2m euros will enable them to continue and expand their research.
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KNAW Early Career Awards for two Leiden researchers
Young Leiden researchers Alisa van de Haar and Marleen Kunneman have received a KNAW Early Career Award. The prize, awarded annually for outstanding achievements, consists of 15,000 euros and a unique work of art.
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Science and business working together on affordable alternatives for antibiotics
Almost fifty scientists and twenty companies will be working on developing new antibiotics and alternatives for antibiotics use. NWO and the Ministry of Health, Wellbeing and Sport will together invest close to seven million euros in this research. Scientists from Leiden University and LUMC will be…
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Hunt for fundamental insight into and treatment for cancer
To develop good cancer treatments, we need to know much more about how malignant tumour cells develop. Professor Ewa Snaar-Jagalska looks at not just the effect of medication on isolated cells but also the behaviour of cancer cells in their tissue environment. Inaugural lecture on 11 December.
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With these small adjustments we can reduce nitrogen loss in peat meadows
Relatively simple adjustments can reduce nitrogen losses on dairy farms in peatland areas. That’s the conclusion of the PhD research by by Leiden environmental scientist Jeroen Pijlman at the Louis Bolk Institute. Protein-poor grass species and narrow-leaved plantain in the grassland can limit nitrogen…
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Skin researcher calls for multidisciplinary collaboration: ‘I want to pool expertise’
In dermatology, there should be a high level of multidisciplinary collaboration among institutes and specialists, Professor of Translational Dermatology, Robert Rissmann, will say in his inaugural lecture on 8 July. He is building an infrastructure that will put pre-clinical and clinical skin research…
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NWO Vidi grant for 11 Leiden researchers
Eleven Leiden researchers have been awarded an 800,000 euro Vidi grant by the Dutch Research Council (NWO). This will enable them to develop their own innovative line of research and start their own research group.
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Ahmed Mahfouz: 'The mystery of brain diseases, unravelled cell by cell'
Which brain cell does what, when Parkinson's disease arises? It won't be long before this jigsaw is solved piece by piece. Ahmed Mahfouz, computational biologist, combines bio-knowledge from Leiden with algorithms from Delft and is getting closer to finding the key.
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Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
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Topic: Psychopharmacology in Health and Medical Psychology
In this research line, the role pharmacological agents and neurochemcial processes play in behavior and cognition is examined with a particular focus on pain, placebo and nocebo effects and intensive care treatments.
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Topic: Placebo effects
The effects of many treatments are determined, to a significant degree, by factors other than the medicine or treatment itself. For example, placebo effects can be equal to the effect size of for example antidepressants or painkillers. Contributing factors are the trust placed in the doctor, the expectation…
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LED3 PhD-Postdoc Symposium 2024
Conference
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Genetic-Tracing of CD8+ T cell fate decisions
PhD defence
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Taking a closer look at resistance to tuberculosis bacteria
Though tuberculosis can be cured today, new resistant strains of the bacteria are becoming a growing problem in the medical world. Biologist Annemarie Meijer and her colleagues are studying resistance to this disease. Their research is already yielding several interesting clues that could help the development…
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LUMC researchers: high levels of lipids in blood protect against allergies
People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…
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Close contact between women and dogs in prehistoric times
Close contact between women and dogs in prehistoric times Women and dogs were in close contact in the neolithic age of hunters-fishers-gatherers. This has been suggested by Leiden osteoarchaeologist Dr Andrea Waters-Rist and fellow researchers who have studied a tiny biological fossil. The fossil was…
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Statement on ransomware incident at NVIC
In the following statement we would like to inform you of a ransomware incident at the Netherlands-Flemish Institute in Cairo (NVIC) in which your personal information might have been involved. The University of Leiden administrates this institute. Related to the transition to working from home as…