1,878 search results for “drug discovery” in the Public website
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New insight into immune cell behaviour offers opportunities for cancer treatment
An international group of scientists has discovered that certain cells of our immune system – the so-called T cells – communicate with each other and work together as a team. To fight an infection they stimulate each other’s growth, but at the same time, they inhibit each other when there is a surplus…
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Tiny, pain-free vaccinations: microneedles and nanoparticles
If it’s up to PhD student Guangsheng Du, patients don’t need to worry about big needles anymore. At the Leiden Academic Center for Drug Research (LACDR), he studied the use of microneedles and nanoparticles as a new vaccination system. ‘I want to create a more patient-friendly delivery method.’ He defends…
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Young transgender people are able to decide about puberty blockers
Young transgender people are able to decide together with their parents on a reversible intervention with puberty blockers. These are the results of a study by LUMC Curium and Amsterdam UMC of 74 young people undergoing treatment. Ninety percent of the young people studied proved able to make an informed…
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Brains react differently to ADHD medication than expected
A tried and tested medication for treating ADHD works differently than expected in the brains of healthy individuals during rest: rather than stimulating brain activity, it suppresses it.
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‘The favourite candidate in the Mexican presidential election is another Trump.'
Mexico will be electing a new president on 1 July. No matter who wins, there will be little change in the deep political crisis affecting the country. This is the message given by José Carlos G. Aguiar, university lecturer in Latin American studies.
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Bio Science Park to become Bio Science Campus
The Leiden Bio Science Park (BSP) will become a real campus in the coming years, with more houses, and attractive places where scientists, students and entrepreneurs can meet to discuss their plans.
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Status update in the evolutionary race between humans and resistant bacteria: two steps forward for us
A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…
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Pain relief without the high
Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set ‘gold standards’ for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications.
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Frank Dikötter to receive honorary doctorate at Dies Natalis 2017
Historian Frank Dikötter will receive an honorary doctorate from Leiden University for his work on the history of the Chinese Republican period and the People's Republic of China under Mao. He will be awarded the honorary degree during the university's Dies Natalis celebrations on 8 February 2017.
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Anti-establishment rhetoric helps win election for Trump
Just one year ago, nobody would have given Trump a cat's chance in the US presidential elections. Now he will be the next President of the United States. Professor of Journalism and New Media Jaap de Jong explains the rhetoric that has got Trump so far.
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Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
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for the beauty of physics
Leiden Physics Poster
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Tapping new markets for rapid DNA unraveller
Researching DNA material for genetic disorders using the most powerful apparatus. This is what GenomeScan, a company on the Leiden Bio Science Park, does. Master's student Konstantina Konstantinopoulou is doing an internship there. 'It's a world where developments happen really rapidly so it's a fantastic…
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Kiem project investigates link between violence and other health problems
‘Violence as a Population Health Problem’ is one of 33 interdisciplinary projects that have been launched thanks to a Kiem grant. The project team will analyse a large patient database to identify links between violence and other health problems. ‘Violence can also be an expression of other factors,’…
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Innovating Cell Pharmacy with stem cells
Lecture
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Polymer‐ and Hybrid‐Based Biomaterials for delivering biotherapeutic molecules in bone and cartilage tissue
PhD defence
- LED3 Lecture: Designing Modulators of Purinergic Signaling for Chronic Disease Treatment
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2018 Hall of Fame
Over the past year, many of our staff and students have won prizes, been awarded a substantial grant or been appointed to an academic association or a position in public life. All of these are good reasons to include them in our 2018 Hall of Fame. We are proud of them all.
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Wall Formula Tours
Arts and culture, Tour
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Neanderthals hunted straight-tusked elephants, 125,000 years ago
A Leiden and Mainz (Germany) based team studies the activities of early humans in a 125,000 years old Last Interglacial ecosystem, formerly exposed in a large open cast brown coal pit near Halle (Germany). The Last Interglacial is an important warm-temperate period, showing the full flora and fauna…
- The internet of 100 years ago
- Open Day
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Computational modeling of pharmacokinetics and tumor dynamics to guide anti-cancer treatment
PhD defence
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Graduation project
Each student chooses an individual topic or theme on which they would like to do a graduation research project. Read the below rules and guidelines before you embark on the graduation project.
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Letters as loot
Linguistic research on a unique collection of Dutch letters allowed us to gain access to the every-day language of people from various walks of life. Private letters by men, women and even children have been elaborately explored in the Letters as Loot researchprogramme, initiated and directed by prof.…
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Tell Sabi Abyad (Syria)
Leiden University and the Netherlands National Museum of Antiquities (Rijksmuseum van Oudheden) are jointly involved in the intensive archaeological exploration of Northern Syria, by means of field surveys and large-scale excavations at a number of archaeological sites in the Balikh basin: the Tell…
- Week 7-8: 19-28 February 2017
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Improving Nature’s Antibiotics to Overcome Resistant Bacteria
Lecture, NGL-lezing
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ICM 2018 project results
Within the ICM 2018 project, Leiden University cooperated with 25 partner universities from 14 countries. In total, 97 mobilities were granted to this project - 65 mobilities were realised (some mobilities had to be ended prematurely due to covid-19, others were finished online).
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Islam and Society
Knowledge of Muslim societies is essential to function in a globalised world and to fully understand our own Dutch society. Leiden researchers explore the languages, cultures, religions, legal systems and history of Muslim societies and in this way contribute to a centuries-old tradition.
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Metagenomic sequencing in clinical virology: advances in pathogen detection and future prospects
PhD defence
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'Only when you give students freedom, exceptional results are possible'
It doesn't happen every day that the research project of a first-year bachelor’s student results in a scientific publication. And not only that, but as first author and on the cover of a leading physics journal. ‘We have given our lab education a thorough overhaul and it is paying off.’
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‘Look beyond your own discipline’
Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.
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Niko Tinbergen lecture 2019: Stem cells, mini organs and eternal life
Three speakers, three fascinating science stories and a well-filled lecture hall. The Niko Tinbergen Lecture had a successful restart on 10 December 2019.
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Rebellious birds make nests from anti-bird spikes
Innovation in nest building: bird nests made from anti-bird spikes. Researchers from Naturalis Biodiversity Center and the Natural History Museum Rotterdam describe this behaviour in a publication.
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Searching explanations for mysterious structures in protoplanetary disks
In the discs of dust and gasses around young stars, mysterious structures occur. Together with professor Ewine van Dishoeck, PhD student Paolo Cazzoletti investigate how we can explain these forms, such as rings, spirals and holes. On 12 December, he will defend his thesis.
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Leiden University involved in five Gravitation projects
Leiden University is involved in five new NWO Gravitation projects. Two relate to mental disorder and the remaining three to a healthy lifestyle, the combination of human and artificial intelligence, and the special relationship between plants and microbes.
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Still learning from the Ancient Greeks
There are still things we can learn from the Ancient Greeks. How they managed to make sure that innovations were accepted, for example. A group of classics scholars, led by Leiden, will be carrying out research on this question funded by the largest ever NWO subsidy.
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Paco Barona Gomez ready to work in Leiden: ‘Fundamental research creates opportunities’
Paco Barona Gomez is the newest associate professor at the Institute of Biology Leiden (IBL). The Mexican researcher is fascinated by the evolution of natural products: compounds made by microbes, but also plants and animals. ‘It’s like we investigate chemical dark matter.’
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Producing new plants without sowing
Producing offspring of a crop without sowing and that is even bigger than the parent plant. According to Leiden researchers this can be achieved by overstimulating a single gene that rejuvenates cells, including bringing them back to the embryonic phase.
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Vidi grants for nine Leiden researchers
From artificial intelligence to letters from the Dutch East Indies and from breast-cancer gene BRCA-1 to the collaboration between government and opposition: nine researchers from Leiden University have been awarded a Vidi grant for their research.
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The Hortus Botanicus: from herb garden to crown jewel
The Hortus Botanicus is celebrating its 425-year anniversary this year. It’s the oldest botanical garden in the Netherlands, but how did it come into existence and what kind of research takes place there?
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Imaging the water snow line within a protoplanetary disc
Research using the ALMA telescope by scientists including Leiden's John Tobin and Steven Bos has produced the first images of the water snow line within a protoplanetary disc. Publication in Nature on 14 July.
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ERC Consolidator Grants for Leiden researchers
Five Leiden researchers have been awarded a Consolidator Grant by the European Research Council (ERC). This grant of up to two million euros will enable them to continue and expand their scientific research.
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Hundreds of fossil tree species belong to a single species
Paleobotanist Menno Booi discovered that 250 previously described fossil tree species are objectively not distinguishable; they belong to only one single species.
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Blog post: The nose of this wormy-shaped bacterium has a surprising symmetry
For the first time ever, Leiden biologists have found that the ‘nose’ of spirochetes – worm-shaped bacteria – have a two-fold symmetry. A remarkable discovery, as the ‘nose’ of every other bacterium has been found to have a six-fold symmetry. First author Alise Muok wrote a popular blog about the findings…
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Gigantic ring system discovered around exoplanet J1407b
Astronomers from the Leiden Observatory and from the University of Rochester (in the US) have discovered that the planetary ring system that covered the very young sun-like star J1407 is actually of enormous proportions. In fact, it’s much larger and heavier than the ring system surrounding Saturn.…
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FLAMINGO: dark matter, ordinary matter, and neutrinos in the biggest cosmological simulation ever
Not only dark matter, but also ordinary matter and dark energy are tracked in the largest ever cosmological computer simulation ever. In the FLAMINGO simulations, you can see virtual galaxies and clusters of galaxies emerging over the course of billions of years. This is no easy task: with more than…
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From bubbles to fuel: could this special soap film soon enable artificial photosynthesis?
A soap film with chemically distinct sides: it's the latest breakthrough in the research led by chemist Sylvestre Bonnet. This unique soap film, along with an innovative device capable of continuously producing new soap films, forms a crucial piece in the puzzle for the development of artificial pho…
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Astronaut André Kuipers touches down at Leiden University
In his guest lecture on 22 January André Kuipers took school pupils and students on trip through space. His mission was to interest his young listeners in science and technology.