'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…

Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…

Sometimes an idea seems so logical and elegant at first glance, that you later wonder why no one thought of it before. Two researchers from LACDR have teamed up to develop a completely synthetic alternative to antibodies—one that mimics their size, shape and function, but which is cheaper, more stable,…

Multidrug-resistant pathogens and worldwide pandemics are increasing, making infectious diseases more prevalent. To develop new treatments, deeper knowledge of the interaction between bacteria and human cells is required. Ariane Briegel recently became a Medical Delta professor and studies such path…

Several consortia in which Leiden University is involved have been awarded Dutch Research Agenda funding. Leiden is the coordinator of five of these consortia. These five consortia will receive grants worth a total of almost 24 million euros. They relate to interdisciplinary projects that will bring…

The Phase 3 clinical trial results of the promising Covid-19 vaccine of Johnson & Johnson are expected this month. The Dutch electron microscopy facility NeCEN helped develop the company’s vaccine, and they have now published their scientific findings in Nature Communications.

Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.

Building more in urban areas is, in most places in the Netherlands, the smartest way to tackle the housing crisis. This is evident from research conducted by Janneke van Oorschot, published in a partner journal of Nature. Remarkably, this does not have to come at the expense of green spaces in cities.…

Are you curious about how the human skeleton works? Discover this and more on 3 October in Leiden and on 4 October in The Hague.

Seven Leiden professors have been elected as members of the Royal Netherlands Academy of Arts and Sciences (KNAW). In total 23 new members will be inaugurated on Monday 13 September.

How do people become involved in terrorist organisations? Liesbeth van der Heide sought the answer to this question in a Malian prison, where she interviewed terrorists in a tiny cell. She discovered that the will to survive and social context are often more decisive than individual ideological convictions.…

Five Leiden researchers have been awarded a Consolidator Grant by the European Research Council (ERC). This grant of up to two million euros will enable them to continue and expand their scientific research.

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

Researchers at LUMC have made a breakthrough in understanding PALB2 mutations, an important cause of hereditary breast cancer.

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…

A true shower of awards for students from the Faculty of Science during the annual KHMW Young Talent Awards ceremony. On Monday, 25 November, no less than nine first-year students received a prize for the best academic results in their first year. In addition, there were graduation prizes for master’s…

Researchers from Leiden University, University of York, University of Barcelona/IQTCUB/ICREA and The Francis Crick Institute report a new class of experimental compounds that powerfully block influenza viruses. The findings offer a potential new strategy for treating flu infections and preparing for…

Chemotherapy, but without hair loss or extreme fatigue. It may be possible if the toxic drug only becomes active where it is ‘switched on’ by light. Matthijs Hakkennes has helped bring that idea closer to reality and obtained his PhD cum laude. ‘I received many thank-you emails from China and Bangla…

Researchers at the Faculty of Science work every day at the frontiers of knowledge, tackling today’s major societal challenges. Their work is recognised through grants, prizes and other awards. We highlight some of these achievements.

Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…

Through its Demonstrator Projects, the Dutch Oncode Accelerator consortium provides grants for preclinical cancer therapy development. The first call for these projects is open until September 2025.

The project will further the development of policies, practices, and capabilities in responsible academic career assessment.

Three Leiden researchers have been awarded a prestigious Vici grant, the Dutch Research Council (NWO) announced on Tuesday. Two of the researchers work at Leiden University and the third at the Leiden University Medical Center (LUMC).

Three of the four Heineken Young Scientists Awards for 2022 have gone to researchers from Leiden: chronobiologist Laura Kervezee, physicist Jordi Tura i Brugués and health psychologist Liesbeth van Vliet.

Last Friday the global Antibiotics Awareness Week begun: an entire week dedicated to antibiotic use. Antibiotics researchers from the LACDR therefore set out to tell primary school pupils about their research. Through role-playing, pupils were drawn into the world of antibiotics: 'Can the teacher not…

Research to experiment with bacteria that grow like plants has been granted the NWO XS grant. These bacteria use light and carbon dioxide to grow, and will be designed especially for use in the biotechnological field. Tijn Delzenne and his supervisor Dennis Claessen can spend 50.000 euros on the exp…

Salt crystals, a nano-sized golf stick and molten glass. The LION Image Award competition of 2023 yielded a lot of beautiful images once again. But in the end, only one can be the winner.

How do you count the nanoplastics in your body? Leiden researchers published a method in Nature Protocols today that should make this easier. Important for both environmental and medicine research.

Sustainable biotechnology, new insights into genome evolution and combining forces in mathematics. The NWO has awarded grants to these three innovative Leiden research projects in the ENW-M Open Competition.

Leiden researchers Arjen Doelman, Tom Huizinga and Manfred Wuhrer have been awarded ERC Synergy Grants worth millions of euros for their research on preventing tipping points being reached in ecosystems and helping eradicate rheumatism.

People who have negative expectations about a treatment actually experience more pain. Merve Karacaoglu discovered in her PhD research that anxious and pessimistic individuals are particularly susceptible to this nocebo effect. However, this sensitivity comes with a silver lining.

From once controversial scientific works and historical bibles, to personal shopping lists and clothing bills. The 17th-century Bibliotheca Thysiana and the archive of the collector Johannes Thysius exhibit both the intellectual and everyday life as it was three hundred years ago. Now a brand-new digital…

The nominees for the IRO Thesis Prize 2025 and the Prof. Dr. J.Th.J. van den Berg-prijs 2025. Who authored the best thesis in Leiden University’s bachelor’s programme in Political Science?

The Dutch Development Bank's new SDG loan fund for green energy in the global south may not be as positive as it seems. Anthropology professor Marja Spierenburg raises concerns about its potential impact on local communities.

An image has great powers of persuasion. It is said that ‘a picture is worth more than a thousand words’. But these days, images can easily be manipulated with severe consequences. ‘Perhaps it’s time to reconsider the value we attach to images’, says Elize de Mul, whose PhD thesis deals with ‘digital…

From academic freedom to security and medical breakthroughs: during Leiden University’s 451st Dies Natalis, the speakers reflected on the role of universities in a world of social and geopolitical tensions.

The Dutch Research Council (NWO) has awarded Vidi grants to 14 Leiden researchers. This grant of a maximum of 850,000 euros will enable them to start a new research group and develop their own line of research over the next five years.

On this page you will find an overview of the main digital tools available for teaching faculty. These tools will help you in different aspects of your teaching, such as online teaching, testing, collaborative learning and creation of video and audio materials.

Lecture, Astronomy on Tap

PhD defence

High-quality education, research involving multiple faculties, collaboration between universities and central government funding to make all this possible: these were the topics covered in a working visit of the Standing Committee for Education, Culture and Science (OCW) to the Association of Universities…

An impressive speech by Dean Jasper Knoester, a lecture by top researcher Mario van der Stelt about brain messengers, and the presentation of the faculty awards. 2025 begins on a hopeful and festive note, with a toast to a year of fruitful collaboration within and beyond the faculty.

What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’

PhD defence

PhD defence

PhD defence

PhD defence

Lecture, Tuesday Talk

Micro- and nanoplastics cause stress to crops such as lettuce and carrots, PhD candidate Laura Julia Zantis found. This can lead to reduced growth and a lower nutritional value. Biodegradable plastics have this effect too, likely because of chemicals they release during degradation.