Recently, it was discovered that glycosylation of glucocorticoids reduces their side effects due to the activity of the enzyme GBA2 at sites of inflammation. I investigate the regulation of GBA2 and its role in the inflammatory response, using zebrafish. Furthermore, I screen novel glycosylated glucocorticoid…

My research is focused on the host-pathogen interplay during infection in Mycobacterium avium and comparing with better studied mycobacterial pathogens like M. tuberculosis and M. marinum. My work addresses two crucial processes in mycobacterial pathogenesis: the intracellular trafficking inside macrophages…

I am professor of Immunobiology and head of the Animal Sciences research cluster. I am interested in host-pathogen interactions and work with zebrafish models for infection with intracellular bacterial pathogens, like Mycobacteria and Salmonella, to study mechanisms of host defence. I am also Confidential…

Our research aims to understand the role of mycobacterial cell wall-deficiency in persistency and pathogenicity in Tuberculosis and to elucidate its molecular regulation for future drug targeting. For this we investigate and characterize cell wall-deficient strains from Mycobacterial species and establish…

My research interest is focused on understanding how biological signal transduction functions at a molecular level. A central theme is the investigation of intercellular communication, particularly the communication of cells of one organism with another. For this a highly multidisciplinary approach…

Rob van Wijk is Principal Investigator “Translational Immuno-Pharmacology” at the Division of Systems Pharmacology & Pharmacy.