About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…

Researchers at Leiden University have created a unique model that mimics how disease develops after a dengue infection. This 'dengue-on-a-chip' model helps them study the virus more effectively. The timing is crucial, as climate change is causing dengue to spread worldwide.

Our lecturers are back on campus sooner than the rest of the staff. Away from their screens and in live contact with students: many lecturers are relieved, but some are concerned. Have sufficient steps been taken at our teaching locations? What about ventilation? We spoke to Michel Leenders who, as…

It’s starting to become a real Dies Natalis tradition: on 8 February professors from Leiden University teach a class at primary schools in the region. This introduces children to academia and teaches them more about conducting research. ‘Had you expected me to be a woman?’

The board of the Pastoor Schmeits Prize for Astronomy Foundation has awarded the Pastoor Schmeits Prize 2025 to two individuals: Yamila Miguel, affiliated to the Leiden Observatory, Leiden University and SRON, and to Else Starkenburg, affiliated to the Kapteyn Institute, University of Groningen. The…

How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.

“Is it possible to restore antibiotic sensitivity in resistant bacteria?” Dr. Tingjie Guo wondered. “Watch me and learn”, phage responded. Dr. Tingjie Guo received an open competition XS domain ENW grant from the Dutch Research Council (NWO) to investigate the evolutionary trade-off of antimicrobial…

A team of LACDR scientists from three different divisions (SPP, BT, MC) contributed to a book on "Substance P in Health and Disease," which will be published by Elsevier. The project was a collaboration with Hannover Medical School (Germany) and was coordinated by Alireza Mashaghi. Master students Ehsan…

An impressive 22 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).

From medicines from snake venom to supercrops and the origin of words. Thirteen researchers from Leiden University will receive Open Competition XS grants from the Dutch Research Council (NWO).

On January 24 Professor Annemarie Meijer and Dr Sander Wezenberg received a NWO grant for their research. The grant was awarded within the Open Competition Domaine Science-M programme and is intended for innovative research areas that can form the basis for the research themes of the future.

Two Leiden researchers have been awarded ERC Proof of Concept grants. These grants, each worth EUR 150,000, will help the grantees in their efforts to bridge the gap from basic science to real-life applications

Organisation, Security

During the coronavirus pandemic, scientists were in a hurry to find drugs that would help fight the disease. To combine the research that was being carried out around the world, PhD candidate Judith ter Schure developed a new statistical method: ALL-IN meta-analysis. This helps determine sooner whether…

Eight scientists from Leiden University have been awarded a grant by the Dutch Research Council (NWO). With this Vidi funding, the researchers can set up an innovative line of research and further expand their own research group over the next five years.

Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.

Nathaniel Martin, Professor of Biological chemistry, wondered what would happen if you take an antibiotic that has been known for 70 years and try to improve it with the latest tools of modern chemistry. Turns out it can become up to a hundred times more potent and prevent the growth of some drug-resistant…

The prestigious journal Science Translational Medicine has published a study by researchers from the Institute of Biology Leiden (IBL) on a potent new antibiotic that can overcome resistance. ‘The idea was to tweak the original antibiotic and create a next-generation drug’, says Nathaniel Martin, professor…

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

Antibiotic resistance is a common problem among patients. The European Project TIPAT trains pharmacologists, microbiologists and immunologists of six universities in interdisciplinary thinking. The ultimate goal is to develop better treatment guidelines to combat resistance. Coen van Hasselt of the…

How can we best treat infectious diseases in people with obesity? Hospital pharmacist and PhD researcher Koen van Rhee studied how obesity affects blood levels of two commonly used medicines. He also developed a method for pharmaceutical companies to test new drugs on this patient group.

Identifying novel antibiotic compounds to tackle antibiotic-resistant bacteria. Researchers from Leiden University and VU Amsterdam will unite through a project now funded by NWO’s Open Technology Programme (OTP), which awarded the collaboration nearly one million euros.

Four researchers from Leiden University have been awarded prestigious Vici grants the Dutch Research Council (NWO) has announced. The honoured applications are from researchers at the Faculty of Social and Behavioural Sciences, Leiden Observatory, the LUMC and the Faculty of Archaeology.

Latin America matters! With its rich history, culture, its impressive resilience and creative innovation in the face of such a diverse array of challenges, Latin America can indeed show the way forward inspiring for positive change. Working together with Latin American institutions, our researchers…

The European Research Council (ERC) has awarded Nathaniel Martin a Proof of Concept (PoC) grant. With it, his group aims to make a dangerous but potent antibiotic less toxic. He receives €150.000.

From Galileo Galilei to Albert Einstein and from Anna Maria van Schurman to Anton de Kom: only a selection of the 25 authors who's books and ideas had extraordinary historical impact, in some cases even to this day. Leiden University Libraries and the National Museum of Antiquities jointly present the…

The Dutch universities as a whole are lobbying for a 'normal' academic year from the end of August, where on-campus teaching will be possible. It's a view that Leiden University shares. Rector Hester Bijl talks about what teaching will be like then. She also looks back on a year of lockdown.

Last week we were informed that Prof. A. Hordijk, emeritus professor at the Mathematical Institute, has passed away. Arie Hordijk (1940) came to the Universiteit Leiden in 1976 and has been a professor of Mathematics of Operations Research at our institute until his retirement in 2005.

Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.