Migraine is a brain disease. If it were simple, we would have solved it already'. That is the title of the inaugural lecture delivered by Professor of Neurology Gisela Terwindt on Friday 3 June. In her speech she emphasises the importance of research into the differences between women and men with m…

Why do some people with adverse childhood experiences develop mental health conditions whereas others do not? A Leiden research project is looking for volunteers aged between 18 and 24 to help us understand more about human resilience.

Leiden professor of Cellular Immunology of Parasitic Infections Maria Yazdanbakhsh receives the prestigious NWO Spinoza Prize this year. This, in many ways, border-crossing scientist contributes with her research to more effective vaccines against parasitic infections and better medication for inflammatory…

Five thousand years before the common era (BCE), Proto-Indo-European, the mother of many languages that are spoken today in Europe, Central Asia and South Asia, originated in eastern Europe. PhD candidate Axel Palmér has combined a 175-year-old hypothesis with new techniques to demonstrate how descendants…

Leiden researchers have discovered an enzyme that helps bacteria feed on everyday plastics. This common enzyme could play a crucial role in future research and eventually in addressing the global plastic crisis. The study was published in Nature Communications.

How do cells repair their damaged DNA—and what happens when that process is hindered and cancer arises? Sarah Moser has taken a closer look during her PhD, uncovering surprising insights that could help improve future cancer treatments.

Acute stress seems to have a surprisingly positive effect on our health. Researcher Erin Faught received an NWO veni grant to find out why that is and how we can use that knowledge to our advantage. For her lab research, she uses a remarkable small animal to learn more about our own stress levels.

This academic year 49 promising international students will start their master’s degree here thanks to a Leiden University Excellence Scholarship (LExS). The students, all from outside the EU, were welcomed in a special ceremony on 5 September. Who are they?

The Dutch Research Council (NWO) has rewarded four projects in which Leiden researchers are bringing science and society closer together. What are these projects?

Within the same species of butterfly many different wing patterns can occur. How is this possible? According to researchers Ben Wielstra and Emma Berdan, of the Institute of Biology Leiden (IBL), the answer lies within supergenes. A supergene is a part of a chromosome that contains many strongly linked…

Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.

A child who receives fewer nutrients in the womb than their identical twin brother or sister is more likely to have developmental problems later in life. This is what researchers from the Leiden University Medical Center (LUMC) write in The Lancet Child & Adolescent Health. This study shows that unfavourable…

Even embryos can become embroiled in an evolutionary arms race with another species. Leiden biologists demonstrate this with larvae of the rosy bitterling that parasitize the gills of freshwater mussels. They published their research on February 19 in PNAS.

For already two years, Vincent Niochet has been affiliated with the Leiden Faculty of Archaeology as an external PhD candidate. Now, he has been awarded an NWO PhDs in the Humanities grant, allowing him to continue his research as a paid PhD staff member. ‘The past two years have been quite challenging,…

Tech giants such as Google, Apple, and Microsoft are increasingly shaping the digital world we live in. Reijer Passchier cautions: 'Urgent measures are needed to curb this influence.'

What causes depression in a child and how can they get over it? Leiden Professor of Psychology Bernet Elzinga and behavioural scientist Carine Kielstra recently hosted a webinar on the subject of depression in teenagers. The level of interest was overwhelming.

Seminars, workshops

Lecture, LUCL Colloquium - Series '24/'25

Webinar, Q&A, discussion

Webinar, Q&A, discussion

Bird, butterfly, fish: when you look through a children’s book, you usually don’t think about the fact that humans divided these animals, depicted in bright colours, into categories. Yet, this division has been discussed for centuries. In her PhD dissertation, Didi van Trijp shows how natural scientists…

The LUMC has become the first institution in the Netherlands to treat a patient with an autoimmune disease using CAR T-cell therapy.

Different groups of hominins probably learned from one another much earlier than was previously thought, and that knowledge was also distributed much further. A study by archaeologists at Leiden University on the use of fire shows that 400,000 years ago knowledge and skills must already have been exchanged…

Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.

Paco Barona Gomez is the newest associate professor at the Institute of Biology Leiden (IBL). The Mexican researcher is fascinated by the evolution of natural products: compounds made by microbes, but also plants and animals. ‘It’s like we investigate chemical dark matter.’

Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…

Is my cap on straight? Where in the cortège will I be walking? These are some of the questions asked by professors joining the Dies Natalis procession for the first time.

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

Archaeological finds off the coast of Java, Indonesia provide insight into the world of Homo erectus, 140,000 years ago. Skull fragments and other fossil remains provide a unique picture of how and where these early humans lived, says Leiden archaeologist Harold Berghuis.

What will it be like to study at Leiden University in 2075? Ten surprising, artistic uni-visions could be brought to life. It’s up to you to vote for your favourite.

Collaboration is worthwhile. A joint LUMC and Leiden Law School project has received €142,500 from the Dutch Research Council (NWO). This grant will advance research into the law and ethics of regenerative medicine.

Four green research institutes in Leiden are joining forces to integrate evolution and biodiversity research, at local and at the national level. Pivot in this collaboration is Frederic Lens.

Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…

What impact does growing up in a musical environment or during the COVID-19 pandemic have on the brain development of teenagers? This was the focus of psychologist Lina van Drunen’s PhD research, which studied hundreds of twins. Her findings reveal that practising music slows brain development, presenting…

Leiden researchers have found clues to why a rare pregnancy disorder is mild in some babies but life-threatening in others. Their discovery opens the door to a test that could identify severe cases during pregnancy. Fortunately, a treatment already exists.

Lots of employees celebrated special successes in 2023. Here’s a list of all those scholarships, awards and honours.

‘A challenging rollercoaster, but also a very bonding and insightful experience,’ that’s how the team of iGEM Leiden 2022 wraps up their participation in the iGEM contest. The contest for synthetic biology climaxed during the Grand Jamboree in Paris. The team ended up in the top 10 of over 360 teams…

Three Leiden professors have recently been awarded the most prestigious scientific accolade in the Netherlands: Maria Yazdanbakhsh and Marc Koper have been awarded a Spinoza Prize and Judi Mesman a Stevin Prize. They received their prizes on 13 October.

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…

People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…

Mirjam Oomens was working on her PhD research on language in the consulting room when she was diagnosed with metastatic cancer. Four years later, she has made it her mission to encourage doctors and other healthcare professionals to make fewer statements about life expectancy. 'Such a conviction can…

One used 3D cell models to study colorectal cancer, while the other used machine learning for more efficient blood donation. For these achievements, Marieke Vinkenoog and Simon Christian Hansmann were awarded the Krijn Rietveld Memorial Innovation Award on Tuesday 2 September.

It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden PhD candidate Samuel Schwab has found that the histones in these organisms are much more diverse than previously thought. Schwab and his colleagues describe…

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

Parents’ talk about new stimuli such as persons or objects strongly affects how avoidant or fearful their child will react. No stronger effect was found when parents had an anxiety disorder or in children with fearful temperaments. Publication by a team of Leiden psychologists in 'Clinical Child and…

PhD candidate Jianhong Zhou aimed to better understand whether and how plant species adapt to environmental changes. She developed two databases that she used to analyze how easily or difficultly plants adapt to changing conditions. Zhou defended her PhD thesis on 4 September.