776 search results for “cancer immunotherapy” in the Public website
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Tazuko van Berkel and Noel de Miranda join Young Academy
Leiden researchers Tazuko van Berkel (Greek and Latin Language and Culture) and Noel de Miranda (Tumour Immunology, LUMC) will join the KNAW’s Young Academy next year. They will be inducted on 22 March 2021.
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Light relief
How can new compounds relieve cancer patients of severe side effects?
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Tumours can use ‘remote control’ to attract blood vessels
Researchers at Leiden University have demonstrated that tumours can apply mechanical means to attract the blood vessels they need to be able to grow. The team published this discovery on 2 March in Nature Scientific Reports.
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Transfusion Medicine and Cellular and Tissue Therapies (MSc)
This joint Master programme will equip you with the necessary competences to play a key role in the emerging field of transfusion medicine. Its current concept includes both transfusion of blood components and hematopoietic transplants, cellular and tissue therapy and immunotherapy. Areas that are integrated…
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Research
An overview of the research at the Cancer Dug Target Discovery group.
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Understanding metastasis: Science Groot grant for Erik Danen
A team led by Erik Danen from the Leiden Academic Centre for Drug Research has received a 3 million euros NWO Science Groot grant to unravel the first steps of metastasis. Danen will work together with biologists and theoretical and experimental physicists from Dutch Universities. ‘Understanding these…
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Mathematics-based strategies for repairing tumour blood vessels
How does the extracellular matrix coordinate endothelial cell behavior during angiogenesis, and how do metabolic waste-products and matrix-degrading enzymes produced by the tumour modify the extracellular matrix so as the change the cellular coordination?
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Molecular Physiology
Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…
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Cell Systems and Drug Safety
The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…
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Anticancer compounds from actinomycetes
How can we find novel natural products from Actinomycetes that act as growth modulators on mammalian cells? Can we harvest and develop the potential of these novel compounds for industrial and medical biotechnology?
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4D Picture project
Helping cancer patients with treatment choices.
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A multi-million grant to keep the biological clock healthy
Dutch researchers are joining forces to conduct research together with a series of societal partners to keep the biological clock healthy in our modern 24-hour society. The BioClock consortium will receive a research grant of no less than 9.7 million euros for this. It is one of the projects that receive…
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Chemotherapy without side effects? It’s possible, with light
Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.
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Tailor-made medicines
More and more medicines are becoming available that target a tumour’s specific traits. The use of chemotherapy is continually undergoing improvement.
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Glycoproteomics assays for prostate cancer biomarker discovery
PhD defence
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Role of Chemokine Gradient Sensing in Ewing Sarcoma Progression, Angiogenesis and Immune Targeting
What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?
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Targeting SUMO Signaling to Wrestle Cancer
PhD defence
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Knowledge of DNA repair in the fight against tumour cells
What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.
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Peter Bouwman
Science
r.j.p.bouwman@lacdr.leidenuniv.nl | +31 71 527 6105
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Elizabeth (Liesbeth) de Lange
Science
ecmdelange@lacdr.leidenuniv.nl | +31 71 527 6330
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The path to individualised breast cancer screening
PhD defence
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Formulation of Peptide-Based Cancer Vaccines
PhD defence
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Monitoring Outcomes In Colorectal Cancer Surgery
PhD defence
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Lateral Lymph Nodes in Rectal Cancer
PhD defence
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Raman Spectroscopy in Bladder Cancer Diagnosis
PhD defence
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Harnessing neoantigens for targeted cancer treatment
PhD defence
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Tailored treatment for colon and rectal cancer
PhD defence
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Identification of regulators of cancer - immune interactions
PhD defence
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Experimental optical imaging during pancreatic cancer interventions
PhD defence
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Dissecting the immune microenvironment of breast cancer
PhD defence
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Metals in Catalysis, Biomimetics & Inorganic Materials
Coordination chemistry is the chemistry of metal atoms
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Drug Discovery and Safety (MSc)
The master's specialisation Drug Discovery and Safety at Leiden University provides students with research-oriented education into the discovery of new drug targets and new lead molecules, particularly in the field of cancer, through a combination of advanced imaging techniques (‘systems microscopy’),…
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Genetic and lifestyle factors in breast cancer prognostication
PhD defence
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Professor Ewa Snaar-Jagalska appointed professor in the field of cellular tumor biology
From the 11th of May Ewa Snaar-Jagalska has been appointed Professor in the field of cellular tumor biology within the Faculty of Science at the Institute of Biology Leiden. Her research focuses on the cellular tumor biology and human cancer modeling in zebrafish
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Topic: The placebo and nocebo effects of communication
We study how communication can heal and harm when patients are confronted with an illness. Most of our studies focus on serious illnesses such as advanced cancer. Communication lies at the heart of medicine, yet we do not always know which specific communication helps patients. Moreover, many complaints…
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ERC grant to improve post-vaccination protection in low-income countries
Maria Yazdanbakhsh, Professor of Parasitology at the Leiden University Medical Centre (LUMC), has been awarded an ERC Advanced Grant of 2.5 million euros. She will investigate why people in Africa and Southeast Asia respond less to certain vaccines than Europeans. Her goal is to find a solution for…
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Prediction of contralateral breast cancer - Statistical aspects and performance assessment
PhD defence
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Optimizing clinical management of T1 colorectal cancer
PhD defence
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Immuno-photodynamic therapy of cancer
PhD defence
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Leiden Early Drug Discovery & Development
Despite recent advances in medicine, many devastating disorders like cancer and cardiovascular, neurodegenerative and infectious diseases still lack effective treatments. In order to address this challenge, we, as scientists from Leiden University, joined hands in the LED3 network. LED3, for Leiden…
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Research
The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Drug Discovery & Safety and Systems Biomedicine and Pharmacology, and the Metabolomics and Analytics Centre.
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Ruthenium-peptide conjugates for targeted phototherapy
As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Mechanisms of Ewing sarcoma metastasis: biochemistry and biophysics
Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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A community effort to assess and improve drug sensitivity prediction algorithms
Source: Nature Biotechnology, Volume 2014, Issue June (2014)
- Leiden Institute of Chemistry
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Development & Disease in Animal Sciences
Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.
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Bioactive Molecules in Animal Sciences
Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.