1,022 search results for “computational modelling” in the Public website
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Maarten van 't ZelfdeFaculty of Science
zelfde@cml.leidenuniv.nl | 071 5275631
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Huub de GrootFaculty of Science
groot_h@lic.leidenuniv.nl | 071 5274539
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Jiahui WangFaculty of Science
j.h.wang@cml.leidenuniv.nl | 071 5272727
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Anyonic, cosmic, and chaotic: three faces of Majorana fermions
In my thesis I study Majorana fermions from three different perspectives. The first one corresponds to non-interacting Majorana fermions that, however, pose non-trivial topological properties. The second one corresponds to strongly interacting Majoranas and the third to relic neutrinos. No one knows…
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Statistical Science
The research programme Statistical Science is concerned with the analysis and interpretation of masses of data, the quantification of uncertainty using probability models, and the development and benchmarking of algorithms and methods with these aims.
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using population pharmacokinetic and physiology based pharmacokinetic modeling approaches
In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.
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Actors at work
Promotor: F.S. de Boer Co-promotor: P. T. de Gouw
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Marije NiemeijerFaculty of Science
m.c.niemeijer@lacdr.leidenuniv.nl | 071 5276105
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Bas ter BraakFaculty of Science
s.j.ter.braak@lacdr.leidenuniv.nl | 071 5272727
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Peter BouwmanFaculty of Science
r.j.p.bouwman@lacdr.leidenuniv.nl | 071 5276105
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Iman GoudarziFaculty of Science
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Stochastic resetting and hierarchical synchronisation
Stochastic resetting is simple enough to be approached analytically, yet modifies stochastic processes in a non-trivial way.
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Seascape Corridors
There is little evidence of the routes connecting Amerindian communities in the Caribbean prior to and just after 1492. Uncovering possible canoe routes between these communities can help to explain the structure, capabilities, and limitations of the physical links in their social and material networks.…
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Gerhard BurgerFaculty of Science
g.a.burger@lacdr.leidenuniv.nl | 071 5274285
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Antiviral Pharmacology
The focus of the Antiviral Pharmacology group led by Anne-Grete Märtson is optimizing antiviral therapy for different viral infections by conducting clinical trials and using innovative computational and dynamic laboratory methodologies.
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Illuminating Host Defence against Mycobacterial Infection: Interactions with Autophagy and LC3-Associated Phagocytosis
Despite substantial progress in understanding tuberculosis (TB), the eradication of the TB epidemic is still far from reach.
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Arguably augmented reality : relationships between the virtual and the real
This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.
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Carlo BeenakkerFaculty of Science
beenakker@lorentz.leidenuniv.nl | 071 5275532
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Optimizing antifungal treatment through pharmacometrics: dosing considerations to enhance outcome
Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.
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Programme structure
This programme is aimed at students who have a strong interest in programming and computer science, as well as an interest in the cognitive psychology and artificial intelligence.
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Processing Lexical Bundles
On the 4th of June, Saskia Lensink successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Saskia Lensink on this achievement!
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Nuclear Quantum Effects in Solid Water
Ice, the solid state of water, plays an important role on our planet as well as the entire universe.Despite the fact that an individual water molecule has a very simple structure, its chemical bonding in the solid phase can be surprisingly complex.
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In silico characterization of a GPCR focused library
Supervisor: Gerard van Westen
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Destroy, Create, Transform and Sublimate. Laboratory Dissociation Studies on Polycyclic Aromatic Hydrocarbons and Analogues
The aromatic infrared bands (AIBs) seen throughout the interstellar medium (ISM) are generally thought to be carried by polycyclic aromatic hydrocarbons (PAHs) and their nitrogen analogues (PANHs).
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Lava worlds: characterising atmospheres of impossible nature
Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune.
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SAILS Lunch Time-seminars
Discover the power of interdisciplinary AI research at Leiden University's SAILS Initiative through this bi-weekly seminar. The SAILS network of AI experts spans all seven faculties: Law, Science, Archaeology, Social Sciences, Humanities, Governance and Global Affairs, and the Leiden University Medical…
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Mechanical Response of Foams: Elasticity, Plasticity, and Rearrangements
Promotor: M.L. van Hecke
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Unfolding the regulation of stress response pathways upon liver injury
Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.
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Virtual children help prevent withdrawal syndrome in real children
When children wean off from heavy medication, they often experience withdrawal symptoms. The severity of these symptoms is often difficult to predict. Pharmacologist Bas Goulooze developed a computer model to determine the best weaning strategy for each child. His research has now been published in…
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange
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Measuring wellbeing in climate and socioeconomic scenarios
Over the past two centuries, socioeconomic development has improved material living standards but has also intensified environmental pressures, including climate change and biodiversity loss.
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G-zips and Ekedahl-Oort strata for Hodge type Shimura varieties
Promotores: S.J. Edixhoven, F. Andreatta
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Structural Health Monitoring Meets Data Mining
Promotor: Prof.dr. J.N. Kok, Co-promotor: Dr. A.J. Knobbe
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Alina KarakantaFaculty of Humanities
a.karakanta@hum.leidenuniv.nl | 071 5272978
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Developing quantum software with a grant of 18.8 million euros
The first larger quantum computers will soon be available. These computers need new software. Researchers at Leiden University have been awarded a Gravitation grant to develop the necessary software. They will be collaborating with colleagues from other research institutions.
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Peter van BodegomFaculty of Science
p.m.van.bodegom@cml.leidenuniv.nl | 071 5277486
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Leiden and Cambridge help create a model course on EU law for Ukraine
Whilst resisting abhorrent Russian aggression, Ukraine has made a clear choice for a future in Europe. With an association agreement already in place, and Ukraine being a candidate for EU membership, Ukrainian lawyers need to be trained in EU law and Ukrainian Law Schools need to develop the capacity…
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Diego Barbosa Arize SantosFaculty of Social and Behavioural Sciences
d.arize@fsw.leidenuniv.nl | 071 5272727
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Juan Claramunt GonzalezFaculty of Social and Behavioural Sciences
j.claramunt.gonzalez@fsw.leidenuniv.nl | 071 5276026
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Agnes SchneiderFaculty of Archaeology
a.schneider@arch.leidenuniv.nl | 071 5272727
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Glucocorticoid modulation of the immune response
Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.
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Multi-Biomarker Pharmacokinetic-Pharmacodynamic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
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Blowup in the complex Ginzburg-Landau equation
Promotor: A. Doelman, Co-promotor: V. Rottschäfer
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Akrati SaxenaFaculty of Science
a.saxena@liacs.leidenuniv.nl | 071 5272727
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Qinyu ChenFaculty of Science
q.chen@liacs.leidenuniv.nl | 071 5272727
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Vision
The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.
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‘Our students are role models for young children in The Hague’
What better way is there for an alderman to find out where best to put his efforts than to pay a working visit to the university? Hilbert Bredemeijer, Alderman in The Hague for Education, Sport and the Outdoor Space, paid a visit to Campus The Hague on Wednesday 6 October 2021.
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CEEDs, the Collective Experience of Empathic Data Systems
The Collective Experience of Empathic Data Systems (CEEDs) consortium developed novel integrated technologies that support experiencing, analysing and understanding of very large datasets.