Primary Objective: The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in comparison to TAU, LF-TLP will result in a significantly…

During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.

This Thesis describes a strategy to synthesize 1,2-cis-oligosaccharides modulated by additives, such as dimethylformamide (DMF), triphenylphosphine oxide (Ph3P=O) and N-methyl(phenyl)formamide (MPF), using building blocks that carry solely benzyl type protecting groups and are therefore of uniform r…

Sorghum (Sorghum bicolor) is a major cereal crop that millions of subsistence farmers in Sub-Saharan Africa (SSA) rely on. However, the scourging impact of the root parasitic weed Striga (Striga hermonthica, a.k.a. “witch-weed”) has remained a major constraint hampering the productivity of sorghum in…

Jaroslaw Kantorowicz and Rok Spruk examine the contribution of institutional reforms to economic growth.

This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.

We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

Intensive public debates have erupted about integration of immigrants in Europe. The influx of refugees from the middle east during the summer and autumn of 2015, the increasing visibility of immigrants throughout European societies, but also the widely publicized occurrences on New Year’s eve in Cologne…

To argue that people can control the relative contributions of goal-driven and stimulus-driven processes to decision-making and action selection.

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Although it is often assumed that the stereochemistry in Ugi multicomponent reactions is determined in the final Mumm rearrangement step, experimental and computational evidence that Ugi reactions on hydroxylated pyrrolines proceed under kinetic control is reported.

Governments in parliamentary democracies have limited time in office to fulfill their policy agendas. So, how do they optimise the timing of legislative bills to assure their passage and avoid lengthy parliamentary scrutiny? This question is especially puzzling under coalition governments, in which…

This thesis describes how different colours of light affect various aspects of the growth and development of Arabidopsis and tomato plants⁠.

Power and money are not enough for big tech entrepreneurs who are investing billions in digital nations. Reijer Passchier, Professor of Digitalisation and the Democratic Rule of Law (OU) and Assistant Professor of Constitutional Law, and Wim Voermans, Professor of Constitutional Law, share their concerns…

China is a one-party regime, yet elections are held for the local congresses. PhD candidate Wang Zhongyuan investigated how the Communist Party uses this democratic instrument to strengthen the authoritarian regime. PhD defence 31 January.

In this article, Gerrit Dijkstra and Jos Raadschelders from the Institute of Public Administration, argue that Bosnia-Herzegovina survives so far on the basis of negative legitimacy.

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

PURPOSE: The aim of the study was to develop a cheap and fast method to produce hollow microneedles and an applicator for injecting vaccines into the skin at a pre-defined depth and test the applicability of the system for dermal polio vaccination.

Promotor: Prof.dr. S. Haring

We found that, next to the effectiveness of the intervention, it’s also very likely that the intervention is cost-effective compared to attention only.

On 12 September 2019, Michiel Rhoen defended his thesis 'Big Data, Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the context of big data'. The doctoral research was supervised by Prof. G.J. Zwenne and Prof.…

The STAP study examines the cost-effectiveness of Written Exposure Therapy (WET) for post-traumatic stress disorder (PTSD) symptoms in primary care settings.

We strive to address the challenge of constructing a modeling language to write software which can take advantage of recent hardware developments (multicore, cloud) without compromising in its abstraction levels.

Nematic liquid crystals form the key ingredients of most tv screens. The active version of these complex fluids forms a useful model for physicists to research the responses of active matter—like bacteria or traffic flows—to mechanical and geometrical cues. An international research team publishes their…

Irna Hofman defended her thesis on 10 January 2019.

The transition period in which men become fathers might provide an important window of opportunity for parenting interventions that may produce long-term positive effects on paternal care and, consequently, child development. Existing prenatal programs traditionally focus on maternal and infant health…

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

Dit proefschrift beschrijft een collectie aan alternatieve strategieën voor het begrijpen, ontwerpen en toepassen van lipide nanosystemen, waarin de rol van de bio-nano interacties centraal staan. In het bijzonder wordt gekeken naar de interactie van RNA-lipide nanosystemen, bekend van de toepassing…

On Friday 7 March 2025 Adam Knight successfully defended a doctoral thesis and graduated.

The central question in this book is whether there is a human right to family unification.

While many healthcare professionals indicate that they frequently use placebo effects and their mechanisms, there is little formal training on how to deal with placebo and nocebo effects in clinical practice. This project aims to address this gap between scientific knowledge on placebo and nocebo effects…

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Promotor: Prof.dr. G.P. van Wezel, Co-Promotor: E. Vijgenboom

Key publications of the Skin Barrier and Vaccination group.

On 3 December 2018 Melanie Fink, Postdoctoral Researcher at the Europa Institute, spoke at the Conference ‘Managing Migration Through Criminal Law Tools’.

What is the effect of training children to exercise self-control? Niko Steinbeis has been awarded a major European subsidy to find the answer to this question. The innovative aspects of this research are the target group, an individual approach to the training and examining the child brain the scann…

Increasing above- and belowground biodiversity in arable leek cultivation to stimulate pest control by natural enemies.

Rigid materials break more easily than floppy ones. This simple observation allows to predict and control the width of cracks. Theoretical understanding of how materials break is useful in for example the production of cars or screens. Publication in PNAS.