Thirty years ago, mutations in the BRCA1 gene were first linked to hereditary breast and ovarian cancer, establishing a genetic basis for cancer development.

Dissociation is a common symptom in borderline personality disorder and is associated with an increased risk of suicidality and self-harm. Dialectical behaviour therapist Anne Krause-Utz has written a book for clinicians, researchers and students who want to better understand and recognise the pheno…

In this thesis, the researcher developed a nanosystem based on the metallophilic Interaction between cyclometalated complexes.

A special type of mirror to reflect X-rays has more possible applications than space research. Targeted radiation therapy for cancer, for example. Next to his full-time job, physicist David Girou mapped out the possibilities. He will receive his PhD on 14 June.

Toward optimal measurement and greater understanding of youth cognition in school refusal and cognitive behavioural therapy outcome

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

Already during their bachelor’s programme, students in Pharmaceutical Sciences are presented with challenging projects. One of these is the Bachelor Research Assignment (BOO in Dutch), which is often their first real experience with scientific research. This means a lot of responsibility and failures,…

The Hazelhoff Centre for Financial Law team regularly publishes in both Dutch and international academic journals and book series.

The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.

ADHD&me is a new cognitive-behavioural therapeutic intervention for young adults (16–25 years old) with ADHD, specifically aimed at improving self-esteem. In this study, we are conducting a Randomized Controlled Trial (RCT) to examine whether this intervention improves self-esteem and whether related…

Indigenous Pasts and the Roman Present

The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…

MT3 is a globally unique programme led by professors and expert authors that covers the most up-to-date knowledge possible in the area of Classical Transfusion Medicine and Cellular and Tissue Therapy. It provides access to high quality knowledge and skills via a completely online system.

The focus of the Antiviral Pharmacology group led by Anne-Grete Märtson is optimizing antiviral therapy for different viral infections by conducting clinical trials and using innovative computational and dynamic laboratory methodologies.

Are you considering starting with the Master's Transfusion Medicine and Cellular and Tissue Therapies? Please feel free to contact us if you have any questions.

Courses cover a broad range of relevant subjects and provide in-depth theoretical knowledge as well as training in practical skills and advanced research tools.

The master's specialisation Child and Adolescent Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.

Effectiveness of an early intervention program for anxiety-prone toddlers in the Netherlands

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

The aim of our research program is to better understand the etiology and course of mood, anxiety and stress-related disorders, such as depression and posttraumatic stress disorder (PTSD). We investigate both the transdiagnostic mechanisms underlying these disorders and work on improving the treatments…

A Dutch consortium has received €6.7 million to accelerate the development of nanomedicines together with patients. Researchers from Leiden University play a key role in the project.

Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…

Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

Below you will find a collection of books, other than those in the BLRN book series, to which members of BLRN have contributed.

To investigate the effectiveness of an online self-help programme for people with HIV and depressive symptoms.

The Leiden Index of Depression Sensitivity (LEIDS) measures cognitive reactivity (CR) to sadness, an aspect of cognitive vulnerability to depression, conceptually similar to rumination.

Doctors should work with patients with bone and soft-tissue tumours to find the best personal treatment strategy says Prof. Michiel den de Sande. He has developed an app that helps choose the right treatment. Van de Sande was appointed Professor of Orthopaedics with a particular focus on paediatric…

Chemotherapy that does nothing until you irradiate it with light. Sylvestre Bonnet receives a Vici grant of 1.5 million euros for the development of this treatment. The Leiden chemist wants to build a new molecule to fight tumours that are at the time still difficult to treat.

In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.

A new therapy for the serious Graft-versus-Host disease

The kidneys play a major role in the elimination of drugs. In children, the exact age-related physiological changes underlying kidney function remain largely unknown.

Find out how to apply for Transfusion Medicine and Cellular and Tissue Therapies.

Therapeutic proteins have revolutionized the treatment of many severe diseases like multiple sclerosis, haemophilia, diabetes and many more. Unfortunately, even recombinant proteins with structures (almost) identical to those of their endogenous counterparts often induce the formation of anti drug antibodies…

Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.

Study information