Strengthening a cancer patient's own immune system so that the body itself can better destroy cancer cells. This is at the heart of immunotherapy, the most promising progress in cancer treatment in recent years. In order to drive this development further, the Netherlands Cancer Institute-Antoni van…

In the research programme Drug Discovery & Safety, we are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

Cynthia van Vonno, political scientist at Leiden University, explains why individual MPs vote according to the party group line.

Professor P.F. (Paul) Wouters has been appointed dean of the Faculty of Social and Behavioural Sciences with effect from 1 January 2019. Wouters has been appointed for a period of three years and succeeds Professor Hanna Swaab, whose second term of office as dean expires this year. Swaab will remain…

It is sufficiently plausible that the professor from the Faculty of Archaeology exhibited the ‘inappropriate and unacceptable behaviour’ detailed in the advice of the investigating committee. That is is unless the professor provides counter-evidence. This is the conclusion of the Subdistrict Court…

A professor from Leiden University, together with a former employee (who is also the professor’s partner), has been guilty of long-term unacceptable and often transgressive behaviour in the form of abuse of power and manipulation. This behaviour led to a culture of fear among staff who were largely…

How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

How effective is eye movement desensitization and reprocessing therapy in targeting epilepsy-related anxiety?

A major challenge in the formulation of biopharmaceuticals is to overcome their inherent instability during production, storage, transportation, handling and administration. We are studying underlying mechanisms of degradation of biopharmaceuticals (including therapeutic proteins, vaccines and advanced…

This Master enables you to practice professional activities such as: lead research projects and develop technically qualified projects in the field of transfusion medicine.

The electrochemical reduction of a group of organic compounds on platinum is strongly dependent on the arrangement of the atoms in the platinum surface. Christoph Bondue, postdoc in Marc Koper's group, published this in Nature Catalysis on 4 March. The reduction of such compounds is an important process…

In order to optimize treatment, it is necessary to closely monitor and manage the patient’s health status by means of ‘precision diagnostics, personalized prognosis and targeted therapy’. The specialisation combines the techniques and applications of these sensing (monitoring) and stimulation techniques.…

A therapeutic vaccine against HPV-16 (type 16 human papillomavirus) improves the survival rate in cervical cancer patients. A new study by ISA Pharmaceuticals B.V. (a Leiden-based biotechnology company) and the Leiden University Medical Center (LUMC) shows that this vaccine produces a more robust response…

The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.

Tuberculosis (TB) is associated with 1.5 million deaths annually. There is a need exists to optimize both current as well as novel antibiotic combination treatment strategies to improve the effectiveness and safety of treatments against TB.

An overview of Quantitative Pharmacology projects

The effects of anthropogenic noise on interactions between predators and their prey are still little understood.

On the 15th of April, Shaoyu Wang successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Shaoyu on this achievement!

PhD defence

Our team is involved in the translation and adaptation of several questionnaires, for research purposes. Information about each questionnaire is listed below.

Imagine how much time, money and discomfort it would save: a personalised treatment for each individual patient. Precision medicine like this is coming ever closer, thanks in part to Elise Dusseldorp’s algorithms. They retrieve a wealth of information from research data.

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

Young people tend to take more risks than children or adults. This trend is related to the reward centre in the brain, which is much more active when they are rewarded, PhD candidate Barbara Braams discovered. Personality, testosterone levels and social context also play a role in risk-taking.

PhD defence

The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.

Registration for the Co-Align 2023 conference is open!

For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.

This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

Elk jaar organiseert het LIBC in samenwerking met de gemeente Leiden een Publieksdag over hersenonderzoek.

Fishes rely heavily on sound to find their way during migration or dispersal. Many species are affected by noise pollution. Hans Slabbekoorn from the Institute of Biology Leiden received a HORIZON2020 grant of 500,000 euros to study the impact of sound conditions on movement decisions of fishes.

How to explain variation in the extent to which parliamentary voting behaviour follows the government–opposition divide? Party Politics article by Tom Louwerse et al.

Does the sitter have agency in the making of a photographic portrait? And if so how?

Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…

The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…

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Governments are increasingly facilitating the roll-out of so-called “smart meters”, a technology for measuring energy consumption that are able to transmit and receive data using a form of electronic communication. However, implementation has been slow or even stalled.

In the public debate on the coronavirus, bold assertions from academics, doctors and other medical practitioners are often heard. For example, that the coronavirus would be no more deadly than the flu. Or that measures to combat the virus like wearing face coverings are unnecessary.

A neuro-ecological perspective on adolescent prosocial development

MHC class I and MHC class II molecules present peptides to the immune system to drive proper T cell responses. Pharmacological modulation of T-cell responses can offer treatment options for a range of immune-related diseases.