Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

The Graduate School of Science offers PhD programmes spanning the entire spectrum of science from Mathematics to Environmental Science.

Engineering an efficient microbial enzymatic polyethylene degradation pathway via an innovative combination of biochemistry and computational biology tools for enzyme discovery and characterization.

Located in the friendly small city of Leiden in the centre of the Netherlands, Leiden University has for centuries been at the forefront of developments in science and that excellent continues today, with world-leading institutes of computer science, mathematics, physics, astronomy, and chemistry. …

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

Please note that the course Molecular Biology for Physics will start on Monday 5 February. Please check the schedules for the time and location!

Learning from nature and utilizing microbial biodiversity to identify and characterize enzymes for degradation and upcycling of plastics and other polymeric materials.

This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…

How does invasive hybridization affect threatened native species?

The Mathematics master’s programme provides a solid theoretical foundation and prepares you to work in multidisciplinary and international environments. With a Leiden Mathematics degree, you’ll have the tools to pursue opportunities worldwide in research, industry, and beyond.

The Mathematics and SCS master specialisation gives you the opportunity to combine Mathematics research with different aspects of science communication.

The Computer Science and SCS master specialisation gives you the opportunity to combine fundamental research in computer science with different aspects of science communication.

The Computer Science and Education master specialisation gives you the opportunity to combine computer science research with an excellent education in becoming a teacher.

Combine research in Computer Science with different aspects of business studies and learn how to build bridges between science and business.

Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…

The two-year research programme Applied Mathematics offers courses at an advanced level. There is a large degree of freedom in choosing one’s own topics. Some of the courses are given at national level, in the Dutch Mastermath programme. The programme concludes with the preparation of a master’s the…

Are you interested in combining your Science master programme with the Education specialisation? Learn more and watch the introduction video.

Are you interested in combining your master programme with the Science Communication and Society specialisation? Learn more and watch the introduction video.

A new mathematical model may explain how body cells get their shapes and what makes them move within a tissue. The model provides fundamental knowledge for applications in tissue engineering, amongst other things. Publication in open-access journal iScience.

New research published in the Journal of Leukocyte Biology suggests that these changes to the behavior of the immune system are persistent and can continue even after diet is improvedAlmost everyone knows that improving your eating habits will most likely improve your health. What most people may not…

The master's specialisation Bioinformatics at Leiden University focuses on research, development and application of computational tools and approaches for expanding the use of biological, medical, behavioral and health data.

Science Internship Fair, a Fair for students and companies to meet up for internships. Matching to find the right student for the right internship. information page for this event at LIACS.

This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).

There are eight institutes at the Faculty of Mathematics and Natural Sciences:

Frank den Hollander has received the Humboldt Research Award of €60,000. He was nominated by two German colleagues with whom he is working together for an extensive period of time. ‘The award was a complete surprise to me.'

The Mathematics and Education master specialisation gives you the opportunity to combine Mathematics research with an excellent education in becoming a Mathematics teacher.

In the Algebra, Geometry and Number Theory specialisation you dive deep into pure mathematics. You explore both the fundamentals and how mathematics is applied in other sciences, society and industry. As a master’s student you join a multidisciplinary research team at the Mathematical Institute and…

Located in the friendly small city of Leiden in the centre of the Netherlands, Leiden University has for centuries been at the forefront of developments in science and mathematics and that excellent continues today, with world-leading department of mathematics, physics, astronomy, chemistry and computer…

Are you interested in combining your Science master programme with the Business Studies specialisation? Learn more and watch the introduction video.

This thesis introduces the concept of

Combine training in Mathematics research with different aspects of business studies. Learn to build bridges between science and business.

The Dutch Michelle Sweering became the best math girl in the world at the International Mathematical Olympiad in South Africa. She is the only girl who won a golden medal.

Everyone can study at Leiden University, at all stages of life: as undergraduate, master or doctoral students in Leiden or The Hague, or short courses with a choice of interesting and diverse subjects. In fact, by sitting in front of a computer at home, now you also take part in free online programs…

The Leiden Institute of Advanced Computer Science (LIACS) offers bachelor and master level education in computer science at Leiden University. We are known for our scientifically based education and for our open atmosphere.

Math girls Jeanine Daems and Ionica Smeets have received the Mr. K.J. Cath prize during the opening of the academic year in Leiden.

Decision support tool for cell therapy commercialization and business development

An examination of academic organization at the forefront of the biotechnology revolution

With a Vici grant of 1.5 million euros, Professor of Mathematical biology Roeland Merks will look for ways to fix messy and leaky blood vessels in tumours. His research combines mathematical simulations and lab experiments in a unique way.

Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen