To explore the potential of marine microorganisms as producers of novel antimicrobial agents and as bioprotectants in aqua- and agriculture, using an integrative, ecology-based strategy for bioprospecting.

Development of Comprehensive and High-throughput metabolomics techniques and Clinical applications of (pharmaco)metabolomics

The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

How can we promote more durable solutions to protracted refugee situations and which roles can connectivity and mobility of displaced people play to improve protection and resilience?

Despite recent advances in medicine, many devastating disorders like cancer and cardiovascular, neurodegenerative and infectious diseases still lack effective treatments. In order to address this challenge, we, as scientists from Leiden University, joined hands in the LED3 network. LED3, for Leiden…

One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…

Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…

To facilitate and accelerate a systemic change in society by creating a framework based on the current post-growth narratives, policies, and initiatives.

The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.

The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology.

The specialisation High-Tech Innovation is for MSc students in Sciences who are interested in interdisciplinary technologies and research related to /important for high technology industries, e.g. the semi-conductor industry or nano-fabrication.

This lecture will be hosted on Thursday, 6 November 2025 at 6:00 pm.

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with the University of Havana.

Arts and culture

On Monday, 4 September the new bachelor programme Security Studies had its official start.

At Humanities, students are the point of focus. They are trained to be critical thinkers, academic professionals and involved citizens. Our lecturers and researchers encourage students to develop knowledge with which they can understand and indicate the major topics in our society. Because everything…

In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

Promotor: Prof.dr. G.P. van Wezel

The shift from response to recovery is now noticeable as the world moves past the paralyzing effects of the COVID-19 pandemic. This book explores responses to the pandemic by international, regional, and local institutions, multilateral action, and crisis prevention efforts at different levels of governance,…

We use DNA strands to stabilize few-atom silver clusters, which show unique optical and chemical properties. This thesis involves the study of these constructs for various applications.

Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent

Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.

The Therapeutic Immunomodulation Group is led by Prof. Johan Kuiper. In this group we aim to identify novel immunologic targets and apply immunotherapy to inhibit or even prevent the development of atherosclerosis.

Western thought has often dismissed shadows as fictional, but what if fictions reveal original truths?

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.

Promotores: Prof.dr. M. Franx & Prof.dr. P.G. van Dokkum (Yale University)

The research of the Biotherapeutic Delivery group led by Joachim Van Guyse focuses on developing novel polymer-based formulations for therapeutic nucleic acid and protein delivery. The research revolves around developing structure-activity relationships between the chemical structure of polymers, the…

Promotor: H.J.A. Röttgering, Co-promotor: G.K. Miley

On 28 June, Jakob Tobing defended the thesis 'The essence of the 1999-2002 constitutional reform in Indonesia: remaking the Negara Hukum. A socio-legal study'. The doctoral research was supervised by Jan Michiel Otto and Adriaan Bedner.

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…

Promotor: A.P.IJzerman Co-promotor: A. Bender

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Appropriate animal models for intradermal vaccine delivery are scarce. Given the high similarity of their skin anatomy to that of humans, minipigs may be a suitable model for dermal vaccine delivery.

The first book ever on information-theoretically secure multiparty computation

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We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.

The Explainatory Data Analysis group develops algorithms and theory that enable domain experts to explain data by finding interpretable patterns and models.

Promotor: G. A. van der Marel, Co-promotor: D. V. Filippov

Joris Larik, Assistant Professor at Leiden University, wrote about the topics of the Brexit, the EU-UK Withdrawal Agreement, and Global Treaty (Re-)Negotiations.

This book presents a thorough analysis of the Kurdistan Region of Iraq’s memory culture, focusing particularly on commemorations and representations of the Anfal and Halabja atrocities.

Galaxies in the Universe are distributed along the intricate framework of the Cosmic Web. Groups and clusters of galaxies comprise the densest regions in this network, and therefore, are excellent cosmic laboratories to study different aspects of galaxy evolution in extreme environments.

Sociopragmatics is a rapidly growing field and this is the first ever handbook dedicated to this exciting area of study.

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

The United Nations Office for Disarmament Affairs (UNODA) has published the 2017 issue in their Civil Society and Disarmament series, titled Voluntary, Non-Binding Norms for Responsible State Behaviour in the Use of Information and Communications Technology: A Commentary. The series aims to provide…

This book offers novel perspectives on the national and international dimensions of the post-war welfare state in Western Europe and North America.