As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.

The new project INFLANET will train young scientists in Europe to become experts in inflammation research. Professor Annemarie Meijer from the Institute of Biology Leiden coordinates the training.

Four scientists from Leiden University have each been awarded a Starting Grant by the European Research Council (ERC). This grant, worth up to two million euros, gives researchers the opportunity to head up a research team for five years.

Biophysicist Rolf Harkes has developed a microscope to optically localize individual molecules in living cells. It improves monitoring of diseases like cancer and Parkinson’s at the cellular level. Defende PhD thesis on t13 January 2016.

In 2021 we will start with a weekly lunch time seminar series, online on Mondays from 12 noon onwards.

The European FET-Horizon2020 LMCat project of Dr. Irene Groot has released a promotional video showing the role graphene could play in our daily lives, how LMCat's production technique works, and how the consortium is capable of taking graphene production to the next level.

Thomas Bakkum en Tom van der Wel, two PhD candidates from the Leiden Institute of Chemistry, have both won poster prizes at the EMBL Chemical Biology Conference 2018 in Heidelberg.

On April 20, sixty participants will take part in LION’s triannual meeting for high school physics teachers, to deepen their knowledge of physics and astronomy and to explore new teaching methods. This edition marks a special occasion, as it is the last meeting organized by Bert van der Hoorn, who will…

Mapping of bacterial genomes to combat infectious diseases

Last Monday April 18, Bram Koster (professor at the Institute of Biology Leiden (IBL), professor at the Leiden University Medical Center (LUMC)) and Ariane Briegel (professor at the IBL) gave a presentation to the mayor of Leiden, Henri Lenferink. The presentation took place at NeCEN, the open access…

Key research articles, reviews and books of the Chromatin group.

Current research at the Skin Barrier and Vaccination group.

The doors of the new Gorlaeus Building are officially open! With an additional lab wing, new lecture halls and offices, a library, a brasserie, and spaces for student associations, the building offers a vibrant and inspiring environment for research, study, and social interaction. Explore on your…

The Dick Stufkens Prize 2025 for best PhD thesis of the Holland Research School of Molecular Chemistry (HRSMC) has been awarded to Begüm Demirkurt for her thesis “Mechanical Contact Imaging using Fluorescence Techniques”. Demirkurt, who obtained her doctorate from the University of Amsterdam last March,…

On Monday 21 September Annemarie Meijer, Professor of Immunobiology, presented her inaugural lecture on immunobiology and infectious disease.

Organ-on-chip technology is used in drug research and customized treatments for patients. Research Institutes and industry join forces within the Institute for human Organ and Disease Model Technologies (hDMT) that was officially launched on May 18. Combining facilities, people and expertise will allow…

The European Research Council (ERC) has awarded chemist Dr Alexander Kros a Starting Independent Researcher Grant of 1.4 million euro. He will be using the grant to study how molecules penetrate the natural barrier of a cell membrane. If his research is successful, it will in time bring about a revolution…

Leiden Physicists have developed a new technique to visualize electrical conductance in sheet-like nano materials. It shows great promise for devices based on a new family of materials—the ‘Van der Waals materials’. The physicists, who won the 2015 Dutch Vacuum Society prize for their work, present…

We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.

Mazène Hochane and Xueying Fan have won the fourth annual LION Image Award. They created a detailed colour image of a human kidney in development.

Leiden University has appointed John van Noort as Professor in Biophysics. He studies the way in which our DNA is folded and read out.

The "Van Marum Colloquia" are a collaborative lecture series between the LION and LIC institutes, focusing on fundamental and applied surface science.

Provenance and distribution of raw materials

Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…

An overview of awards and prizes granted to our staff and students in 2019, as well as special appointments and royal distinctions.

An overview of awards and prizes granted to our staff and students in 2018, as well as special appointments and royal distinctions.

Eleven Leiden researchers have been awarded an 800,000 euro Vidi grant by the Dutch Research Council (NWO). This will enable them to develop their own innovative line of research and start their own research group.

PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.

Making all those things we normally cannot see visible is the challenge that fascinates Fons Verbeek, Leiden's new Professor of Computational Bio-Imaging. Contributions from chemistry, optics and in particular computational sciences to making and processing these images give greater insight into the…

Recently, NWO has decided to grant two interdisciplinary research proposals for national and international consortia submitted by researchers from the Institute of Biology Leiden. One of the proposals is led by Prof. dr. Ariane Briegel, the other one by dr. Remko Offringa.

Manufacturers produce high-end technology mostly top-down with large machinery, but small particles are able to build structures by themselves from the bottom up. A major challenge is that these particles easily clump together. Leiden physicist Daniela Kraft has developed a method to use this phenomenon…

Neanderthals in cold regions probably ate a lot more vegetable food than was previously thought. This is what archaeologist Robert Power has discovered based on new research on ancient Neanderthal dental plaque. PhD defence 1 November.

The bacterium Vibrio cholerae is a serious threat to our health because it is the causative agent of cholera. Worldwide, over a billion people per year are at risk of cholera infection. New strains of V. cholerae are resistant to the multiple drugs used to treat cholera, meaning that new types of drugs…

In the week of 22 May, a delegation of the Faculty of Science visited Indonesia to strengthen the cooperation with the Universitas Gadjah Mada, the Universitas Indonesia and the Kebun Raja (botanical garden) in Bogor. Furthermore, the delegation visited the faculty of Pharmacy of the Institut Teknologi…

Biologists today have to be able to work with big data. Data analysis skills should be taught from the start of the degree programme, or - even better - in secondary school. This is the message of Vera van Noort, new Professor of Computational Biology. Inaugural lecture 22 January.

Mysterious protein fibers show up in the brain cells of people suffering from Alzheimer’s' disease and other neurodegenerative disorders. Leiden physicist Louise Jawerth has been awarded a Vidi grant to find out how these fibers form in the first place.

Sugar excipients, needed to stabilize medicines, can be unsafe for patients due to an impurity discovered recently by Daniel Weinbuch. ‘The biopharmaceutical industry should now consider new excipient quality criteria for safer drug development,’ he says. PhD defence on 13 December.

A certain type of oil droplets changes shape when cooled and shrunk: from spherical through icosahedral to flat hexagonal. Two competing theories couldn't fully explain this, but now, a Physical Review Letter by Ireth García-Aguilar and Luca Giomi solves the mystery.

Chinese universities have big ambitions to be among the leading international higher education institutions. What does this mean in terms of opportunities for researchers at the universities of Leiden, Delft and Rotterdam? Staff at the universities recently discussed the issue.

Nanodiamonds and charcoal in Dutch soil provide no evidence for the alleged impact of a meteorite at the end of the last Ice Age. This is the conclusion of a research done by Utrecht University in collaboration with Leiden University and the University of Groningen.

Lecture

Lecture

Gold nanoparticles give us a better understanding of enzymes and other molecules. Biswajit Pradhan, PhD candidate at the Leiden Institute of Physics, uses gold nanorods to study individual molecules that would be challenging to detect otherwise. Resulting knowledge can be applied to many research fields,…

On Friday 28 October, Leiden University organized its annual Physics Ladies Day for female high school students. To mark this festive day, we put the spotlight on four female researchers, who talk about their experiences in physics.

The cellular recycling system in zebrafish is capable of eating harmful bacteria and thus resist infections such as tuberculosis and salmonellosis. That is written by Leiden biologists from the group of Annemarie Meijer. Stimulating this form of defence could be used in new treatment methods against…

Both Leon Jacobse and Thom Hersbach from Marc Koper's research group obtained their PhDs cum laude. They both investigated changes on the surface of a platinum electrode. Jacobse studied this at a positive voltage, Hersbach at a negative voltage. Platinum has the potential to convert renewable energy…

For the first time ever, Leiden biologists have found that the ‘nose’ of spirochetes – worm-shaped bacteria – have a two-fold symmetry. A remarkable discovery, as the ‘nose’ of every other bacterium has been found to have a six-fold symmetry. First author Alise Muok wrote a popular blog about the findings…

Catalysts are indispensable in everyday life. We know what they do and more or less how they do it, but we still lack a fundamental understanding about their functioning at an atomic scale. Therefore, Irene Groot from the Leiden Institute of Chemistry develops new measuring techniques to unravel the…

Joost Beltman (LACDR, Leiden University) has provided novel insights in the way T cells migrate towards virus-infected cells. This was accomplished by a combination of experimental research in the group of Ton Schumacher (Dutch Cancer Institute, NKI) and computer simulations in collaboration with Rob…

Just about everything that's known about Charles Darwin has already been said or written. Even so, Norbert Peeters – together with Tessa van Dijk – has managed to write an original book about the great English scholar. In the run-up to Darwin Day (12 February) he tells us about his new book.