Theoretical physicist Luca Giomi receives a 2 million euro ERC Consolidator Grant for research into flowing cells in a strange hexatic phase, which is half fluid, half solid.

Chemotherapy, but without hair loss or extreme fatigue. It may be possible if the toxic drug only becomes active where it is ‘switched on’ by light. Matthijs Hakkennes has helped bring that idea closer to reality and obtained his PhD cum laude. ‘I received many thank-you emails from China and Bangla…

On Friday 3rd June, the Europa Institute hosted a Leiden Law Exchange (LLX) on the British referendum on membership of the European Union. In a roundtable discussion, academics, policy makers and other experts engaged in a lively debate on the legal and political implications of a ‘Brexit’ or a ‘Bremain’…

The headline of the Financial Times on 5 May – 'Northern Ireland tensions threaten to derail Brexit long-term EU-UK deal' – was greeted as a blast from the past. This blast from the past led to the EU requesting to set up an office in Northern Ireland. Joris Larik, Assistant Professor at Leiden University…

The Leiden Institute of Physics has been awarded three out of twelve available grants from the FOM Projectruimte. Principal Investigators Milan Allan, Stefan Semrau and Carlo Beenakker all receive around 400,000 euro for their research.

Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.

The DASPO-group for data analysis and survival in personalized sarcoma at the Mathematical Institute has developed an app that provides personalised predictions for patients suffering from soft tissue sarcomas. Due to the aggressive nature of such tumors, the prognosis for such patients is poor, even…

A month ago it was Marc Baggelaar, and now Hans Kistemaker too has obtained his PhD cum laude at the Leiden Institute for Chemistry (LIC). ‘He has made ground-breaking contributions to the world of protein modification,’ says PhD supervisor Gijs van der Marel. Kistemaker obtained his PhD on 11 May…

Chemotherapy that does nothing until you irradiate it with light. Sylvestre Bonnet receives a Vici grant of 1.5 million euros for the development of this treatment. The Leiden chemist wants to build a new molecule to fight tumours that are at the time still difficult to treat.

Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.

Doctors should work with patients with bone and soft-tissue tumours to find the best personal treatment strategy says Prof. Michiel den de Sande. He has developed an app that helps choose the right treatment. Van de Sande was appointed Professor of Orthopaedics with a particular focus on paediatric…

Lecture

Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…

Key publications of the Cancer Drug Target Discovery group

New or improved treatments for chronic and acute illness.

Find out about the effects of Brexit on contracts and supplies.

This book discusses theories of crisis management and the radical right, to shed light on how responses to crisis influence radical right parties in their presence, discourse, and evolution. The book offers a comparative perspective by examining case studies with various traditions of radical right…

Lecture, CHEI Seminar

On 21 April 2021, Armin Cuyvers lectured students and staff of the University of Nairobi on EU law and comparative regional integration.

On 6 June, Armin Cuyvers lectured students and staff of the University of Nairobi on EU law and comparative regional integration

Improving health, enhancing well-being and reducing health disparities across society.

Teaching is a vital part of CompaRe’s activities. Both in Leiden and abroad, our aim is to educate the minds that will redesign and drive forward the regional integration of tomorrow. We do so by offering multiple courses on comparative regional integration in Leiden, the creation of a MOOC on comparative…

More and more medicines are becoming available that target a tumour’s specific traits. The use of chemotherapy is continually undergoing improvement.

Pathways of toxicity

What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.

PhD defence

Find out more about the impact of Brexit on research projects.

The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Cell Systems and Drug Safety, Medicinal Chemistry and Systems Pharmacology and Pharmacy, and the Metabolomics and Analytics Centre.

Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…

Coordination chemistry is the chemistry of metal atoms

Pancreatic ductal adenocarcinoma (PDAC) is the deadliest common cancer, with only 8% of patients surviving for five years. One reason for this poor outcome is that current chemotherapy treatments are highly toxic, often leaving patients too sick to receive treatment or forcing doctors to lower the dose…

Helping cancer patients with treatment choices.

One Lecture about Immigrant Integration in the EU and its Member State at the Institute of European Studies at George Washington University, one class in a course on Immigration and Integration at Georgetown University, and a lot of judging in the international rounds of the Phillip C. Jessup International…

Joost Beltman (LACDR, Leiden University) has provided novel insights in the way T cells migrate towards virus-infected cells. This was accomplished by a combination of experimental research in the group of Ton Schumacher (Dutch Cancer Institute, NKI) and computer simulations in collaboration with Rob…

The Europaeum is a network of 17 leading European universities, whose aim is to bring together talented students and teachers and to promote a 'European feeling' through cooperation and academic mobility.

Eva Michaels & Monika Sus examines European Strategic Autonomy (ESA) as the EU’s response to the fragmentation of the Liberal International Order.

We study how communication can heal and harm when patients are confronted with an illness. Most of our studies focus on serious illnesses such as advanced cancer. Communication lies at the heart of medicine, yet we do not always know which specific communication helps patients. Moreover, many complaints…

PhD defence

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

Our research in the area of safety sciences aims to increase the mechanistic understanding of cellular toxicity of drugs and, in a broader sense, chemicals.

PhD defence

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

Source: Nature Biotechnology, Volume 2014, Issue June (2014)

Overkleeft

These awards honour researchers who turn scientific insight into real-world impact. From master’s students to postdocs, they highlight exceptional work in life sciences, health sciences, biotech, or environmental health sciences with data science at the core. Meet the 2025 winners.

On 29 January 2019, CBC News, Canada’s largest news broadcaster, interviewed Dr. Joris Larik about the status of the Comprehensive Economic and Trade Agreement (CETA) between the EU and Canada.