1,678 search results for “leiden in het herman” in the Public website
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Mechanical and genetics basis of cellularization and serosal window closure in Tribolium castaneum
The applications of studying the early development of insects range from agriculture to material science.
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Targeting lipid metabolism to develop host-directed therapeutics for mycobacterial infections
Our research aims to develop drugs that boost the host immune response to better defend us against mycobacteria.
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Tail Regeneration in the Tokay Gecko (Gekko gecko)
Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.
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Innate immunity, developmental speed and their trade-offs in two hexapod models
This thesis focuses on important life history traits and their trade-offs using two hexapod models. Particularly, the trade-off between immune defense and embryonic developmental speed is a central theme of this study.
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"No one has yet determined what the body can do": the turn to the body in Spinoza
A comparative study in the History of Modern Philosophy focused on the recourse to physiology on the part of two key figures, Spinoza and Nietzsche.
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Biophysical feedbacks between seagrasses and hydrodynamics in relation to grazing, water quality and spatial heterogeneity
Consequences for sediment stability and seston trapping
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Towards a mechanistic understanding of nanoparticle behavior using zebrafish
The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.
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A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
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Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
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Surviving embryogenesis: The extraembryonic serosa protects the insect egg against desiccation and infection
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee
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On the road to justice: some selected suggestions for the future of Social Justice Research
In September 2023 Social Justice Research, a journal from Springer Nature, published a ‘Special Issue on Veteran Reflections’. Eight ‘veterans’ analysed the current status of justice research and suggested new directions and refinements. Herman Steensma, guest member of the section Social, Economic…
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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In vitro and in vivo evaluation of synergistic and opposing effects of Chinese herbal medicine and natural compounds on immuno-modulation.
Can we link multiple components from herbal extracts with their biological activities?
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Conflict and Contest in Nietzsche's Philosophy
While Nietzsche's works and ideas are relevant across the many branches of philosophy, the themes of contest and conflict have been mostly overlooked. Conflict and Contest in Nietzsche's Philosophy redresses this situation, arguing for the importance of these issues throughout Nietzsche's work.
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The developing infant gut microbiota: mathematical predictions of the effects of oligosaccharides
A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Ecology and genomics of Actinobacteria and their specialised metabolism
Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Genomics applications of nanopore long-read sequencing for small to large sized genomes
In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…
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Nietzche's Rejection of Stoicism; A reinterpretation of Amor fati
Nietzsche's famous notion 'amor fati' is often associated with the Stoic maxim to 'live in accordance with nature'; we have to fully accept our fates in order to attain happiness. But is happiness really what Nietzsche's 'amor fati' is about? And how to account for all the fiercely critical remarks…
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Contact
Do you have questions about the specialisation Molecular, Cellular and Organismal Biology? Please contact us.
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Nietzsche’s Engagements with Kant and the Kantian Legacy
Nietzsche has often been considered a thinker independent of the philosophy of his time and radically opposed to the concerns and concepts of modern and contemporary philosophy. But there is an increasing awareness of his sophisticated engagements with his contemporaries and of his philosophy's rich…
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Key innate immune components controlling intracellular infection
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
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Being a Slave: Histories and Legacies of European Slavery in the Indian Ocean
Being a Slave brings together scholars and writers who try to come to terms with the histories and legacies of European slavery in the Indian Ocean.
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Scholarly Dogmatism: A Rhetorical History, 1800-2000
This project traces how, why, and under what circumstances scholars invoked the trope of “dogmatism,” especially in controversies. Relevant controversies from various fields, periods, and countries will be subjected to in-depth rhetorical analysis.
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Bakti and Sayan traditions among the Tenggerese people in East Java: the role of indigenous institutions in integrated elderly care development
This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…
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Kearifan Kesehatan Lokal: indigenous medical knowledge and practice for integrated nursing of the elderly with cardiovascular disease in Sumedang
The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.
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Historicism: A Travelling Concept
Throughout the twentieth century, scholars, artists and politicians have accused each other of “historicism.” But what exactly did this mean? Judging by existing scholarship, the answers varied enormously. Like many other “isms,” historicism could mean nearly everything, to the point of becoming mea…
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Ancient Networks
The archaeology of transregional exchange (1st millennia BCE-CE)
- The Belgian Archaeological Mission to Elkab
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What is papyrology?
Greek papyrology is the science that is concerned with deciphering and studying all texts written in Greek on papyrus. Papyrus was the writing material of antiquity and was made from strips of the papyrus plant stuck together.
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Dr. H. Enno van Gelder lecture and research grant 2021
Met de H.E. van Gelder Onderzoeksbeurs wordt beoogd interdisciplinair onderzoek naar munten, bankbiljetten en penningen van een impuls te voorzien. De beurs heeft een waarde van € 10.000 en stelt de onderzoeker (m/v) in de gelegenheid een publicatie voor te bereiden en aan de hand daarvan vervolgonderzoek…
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Journalistiek in Irak tweegesprek met Judit Neurink en Sakir Khader
LUCIS organiseerde op woensdag 4 maart een speciale avond over journalistiek in Irak. Journaliste Judit Neurink en programmamaker Sakir Khader vertelden over hun ervaringen en recente werkzaamheden in het land. De avond stond onder leiding van Wendelmoet Boersema (politiek redacteur van dagblad Trou…
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Live blog as genre in pursuit of credibility
On the 3rd of April, Sebastiaan van der Lubben successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Sebastiaan on this achievement!
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Findings
We are currently gathering information about how safe Leiden’s residents feel. To do this, we are using online surveys that give us an idea of perceptions of safety in Leiden.
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Optimal Test Statistics for Anytime-Valid Hypothesis Tests
Vandaag de dag liggen statistische methodes aan de grondslag van beslissingen in allerlei facetten van het leven, van de gezondheidszorg en agricultuur tot de financiële sector en marketing.
- Selected references
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Professor Joke Bouwstra elected as KNAW member
Professor Joke Bouwstra has been elected as member of the Koninklijke Akademie van Wetenschappen (KNAW, The Royal Dutch Academy of Sciences). This is a very prestigious recognition and a great honor for Joke. You can find the announcement by the KNAW below (short version) and as an attachment.
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Media on the dissertation of Wimar Bolhuis
Electoral promises are not always realized in the coalition agreement, and that is often at the expense of households. On an average they pay 4 billion euros more than planned. That is what the PhD research of Wimar Bolhuis shows. Several media reacted on his PhD research.
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Wetenschappers ontdekken hoe darmbacterie resistent wordt
Een minuscuul cirkelvormig stukje DNA zorgt ervoor dat de darmbacterie Clostridioides difficile resistent raakt tegen een veelgebruikt antibioticum. Dat ontdekten wetenschappers van het Leids Universitair Medisch Centrum (LUMC) nadat artsen hen attendeerden op een patiënt met een moeilijk behandelbare…
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Forty years of Leiden environmental science
They were called 'annoying brats', the group of campaigning scientists who in 1978 founded what is now an internationally acclaimed ecological research institute. Their stories and those of the current staff of the Institute of Environmental Sciences are described in the book 'Forty years of Leiden…
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Evaluatie Wet homologatie onderhands akkoord
In juli 2024 is het boek 'Evaluatie Wet homologatie onderhands akkoord' uitgebracht. Het boek bevat het rapport van het evaluatieonderzoek van de Wet homologatie onderhands akkoord (WHOA) uitgevoerd door een onderzoeksteam van de Rijksuniversiteit Groningen en de Universiteit Leiden in opdracht van…
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Welmoet Wels wins the faculty Jongbloed thesisprize 2015
The world is full of wars, and no war is without its dead. What happens to the bodies of fatal casualties of armed conflict? The winner of the faculty Jongbloed Thesis Prize 2015 is Welmoet Wels (Public International Law). Her thesis Dead body management in armed conflict: paradoxes in trying to do…
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European Integration in Finance
How should European financial law best integrate considering the interaction of the relevant legal systems?
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Optimal Teaching
The better teaching is for pupils and students, the more solid the basis will be that we give them for their future careers. This type of teaching requires strong instructors and insight into the best ways in which pupils can be supported, and research at Leiden University is making a contribution in…
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The Hague student city
The Hague is a fast-growing student city in the Netherlands, offering great study and career opportunities to students from all over the world.
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Responding to pupils with mild intellectual disability in education
Mariëtte Huizinga, Dorien Graas and Anika Bexkens call attention to learning problems of children with mild intellectual disability in the classroom. Their new book aims to make it easier for teachers to respond to the specific educational needs of these children.
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Book presentation 'Opportunities in the Kingdom'. 200 years of student financing
On Monday, 1 February a beautifully designed and accessible book appeared about two centuries of student financing and apprenticeship in the Netherlands, entitled Kansen in het Koninkrijk (‘Opportunities in the Kingdom’). The book was presented to Job Cohen, a Leiden University professor and chairman…