The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

A study of the technology, form, function, and use of pottery from the settlements Uitgeest-Groot Dorregeest and Schagen-Muggenburg 1, Roman Period, North-Holland, the Netherlands

Much attention has been paid to the exchange of objects, ideas, and people in the Caribbean. Networks of interaction connected local communities across pan-regional scales, shaping indigenous socio-political integrations and their responses in colonial situations. This work examines the poorly understood…

Part of ‘Moralising Misfortune: A Comparative Anthropology of Commercial Insurance’, an ERC Consolidator project of Erik Bähre.

This book offers a comprehensive and accessible introduction to a novel theory of syntax, which analyzes grammar from a semantic perspective.

On May 2nd, Elena Karvovskaya succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Elena on this great result.

The Co-Align Conference 2023 will be held on 16 May 2023 at Leiden University.

The main topic of the book is the nature of inner aspect of the Verb Phrase, and the relation between the decompositional and the quantificational approaches to this problem.

The basic concern that informs every part of the research is in wonder of what happens when sound happens as an aesthetic force. The emphasis of each query lies on the active occasion, the radical empiricism, the moment of encounter, how the sonic event comes to pass as aesthetic force.

This dissertation explores how Large Language Models (LLMs) can effectively and responsibly contribute to complex decision-making processes. By combining AI and human intelligence, Hybrid Intelligence (HI) emerges, allowing the strengths of both humans and machines to be utilized.

This thesis studies the geometry of representation varieties and character stacks. These are spaces parametrizing the representations of a finitely generated group, typically the fundamental group of a compact manifold, into an algebraic group G.

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Comparing Mycenaean tomb building with labour and memory

Paisaje, cerámicas e interacciones

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

This is the first special issue of any organisation studies journal on food labour. Why is this a big deal? In this Introduction, we argue that the field should pay much more attention to the agri-food system and the work that goes into producing, distributing and consuming foodstuff. Food is such an…

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: Dr. A. El Ghalbzouri

Promotor: F. Arbab

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

This study looks at the question of how and at what level students in primary teacher education can integrate theory and practice, and how the organisation of their learning environment, focusing especially on mathematics and pedagogy, can contribute to that.

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

Promotores: J.C. van Houwelingen, S.A. van de Geer

The Hague Journal of Diplomacy (HJD) is the world’s leading research journal for the study of diplomacy and was founded in 2005. The journal is published by Brill.

On November 22nd, Morana Lukač succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Morana on this great result.

If Gerard Fieret’s photography has been unjustly ignored until recent exhibitions in New York, Amsterdam, and Paris, his poetry continues to be unknown outside of the Netherlands. Across more than ten published collections, Fieret gives form to a body of poetry in which a desire to record the urban…

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

This thesis investigates Søren Kierkegaard’s place in Martin Heidegger’s first Freiburg period lecture courses.

This reflection for Critical Studies on Terrorism, explores two decades of the 'War of Terror' and what it means today.

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

To what extent are individuals socialised with heteronormativity and gender norms by the national context in which they live, by Dutch schoolbooks, and within Dutch families?

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

This book presents a comprehensive description of the grammar of Logba, one of the fourteen Ghana-Togo Mountain (GTM) languages spoken by approximately 7,500 speakers on the South-Eastern frontier of the Ghana-Togo border. It is the outcome of fifteen months research in Logba speaking communities.

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

We study expressions of emotion and social decision making across species.

Kamerlingh Onnes Building, Steenschuur 25, 2311 ES, Leiden

This thesis investigated the extent to which participation of school students in decision-making processes can be achieved, including through participatory action research (PAR) in teacher education.

On the 5th of September, Zhen Li successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Zhen on this achievement!

The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

While many European universities, Leiden included, have a proud tradition of research into Islamic studies, a topical and thematic focus on Shiʿi Islam in all its dispensation remains a desideratum.

This paper explores the long-term endurance of “breath” as a schema of personhood in the Austronesian-speaking world, from a comparative-ethnographic approach to the “Man with No Breath” figure featured in Philippine epics. This is one of two contributions from Myfel D. Paluga and Andrea Malaya M.…

Human skin equivalents (HSEs) can be a valuable tool to study aspects of human skin, including the skin barrier, or to perform chemical or toxicological screenings.

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

This special issue of Contemporary Levant critically explores, at a micro and macro level, the structural role and religious, cultural and political interactions of the Greek-Orthodox, Melkite and Syriac communities in late Ottoman and Mandate Syria and Palestine.

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

On 21 September 2022 H. Hu successfully defended a doctoral thesis and graduated.

This article examines the position of victims and those affected within communication theory. Current research has broadly been skewed toward reputation management and protecting brand value as primary goals of crisis communication efforts. The authors offer recommendations for crisis communication…

Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.