1,062 search results for “optimize drug design” in the Staff website
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Artificial microswimmers work together like bacteria
Microscopic swimmers such as bacteria do not always swim alone. There are advantages to exchanging information and cooperating. Stefania Ketzetzi and colleagues now show in Nature Communications that human-made microswimmers, too, can cooperate.
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‘Sleep should play a greater role in lifestyle research’
Sleep disorders have a significant influence on our physical and emotional health. Sleep should therefore receive more attention within lifestyle medicine, says Professor Gert Jan Lammers. He will give his inaugural lecture on Friday 20 May entitled: ‘Getting to sleep’.
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Leiden researchers visualise the 'guardian of our genome’
The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…
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New track 'Governance of Violence' addresses need to conduct violence specific studies
The sixth specialisation of the Master Crisis and Security Management (CSM) will start in September 2023: Governance of Violence. Coordinator of this track is Professor Marieke Liem. She talks about the how and why of this new track and the importance of research in and knowledge of the nature and scope…
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PhD Graduate Van Groesen: ‘Nothing is too crazy to try.’
In a world where bacteria are increasingly resistant to antibiotics, Emma van Groesen set out to find a solution. This month she obtained her PhD, after four years of research into new variants of the antibiotic vancomycin. With success.
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Can we live longer? Leiden physicist makes discovery in protective layer in genes
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…
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Kiem project investigates link between violence and other health problems
‘Violence as a Population Health Problem’ is one of 33 interdisciplinary projects that have been launched thanks to a Kiem grant. The project team will analyse a large patient database to identify links between violence and other health problems. ‘Violence can also be an expression of other factors,’…
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Extraterrestrial life, AI and more: these are the most-read Leiden Science articles of 2025
Speculation about alien life, a new nitrogen map, AI as a thesis supervisor, groundbreaking telescopes and multi-million-euro investments to combat antimicrobial resistance – the diversity of these topics shows that our readers are just as broadly interested as our researchers. Discover the most-read…
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CellEKT: a chemical proteomics platform to study the kinome
PhD defence
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Mutation-Driven Modulation of GPCR Pharmacology: Insights from Adenosine and Serotonin Receptors
PhD defence
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Teaching Tips to improve your work balance
Work balance has been a hot topic at the faculty for several years. A smart approach to lectures can help reduce workload. Three (senior) university lecturers share their tips.
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NWO funding for five FWN projects within the Dutch Research Agenda
Can humans perceive single photons? What is our place in the universe? How can we make quantum computers more stable? Five researchers from the Faculty of Science have received funding for their research projects within the Dutch Research Agenda (NWA).
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A call about: project Return to the campus
In this time of Covid-19, our way of working has changed. Many staff who used to work on a PC, and who now work from home with a laptop provided by the employer, are now returning to the office and this is having an impact on the university network: the WiFi network in particular will be a bottleneck.…
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Digitised Chinese mega-maps now available in Open Access
Three enormous maps of China, created during the reign of three different emperors of the Qing dynasty, have now been made available in open access and are downloadable via Leiden University Libraries’ (UBL) Digital Collections. The rich maps are an early example of academic collaboration between the…
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'It’s the complexity of this group of patients that makes the challenge of improving their quality of life so interesting’
Dialysis patients experience a range of physical and mental symptoms that interact and influence each otherIn her doctoral research, psychologist Judith Tommel wanted to find the optimum approach to help these dialysis patients improve their quality of life. ‘We need to make sure we avoid excluding…
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Celebrating female computer scientists: ‘Computer science is for everyone’
Four female computer scientists share a common goal: to showcase the significant contributions of women in computer science and inspire their students. Together, they are organising this year’s Alice & Eve event, a one-day symposium dedicated to celebrating women in computer science. The event, scheduled…
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Programme innovation at Dutch Language and Culture
In 2018, the undergraduate programme Dutch Language and Culture embarked on sweeping programme innovations to educate its students ‘in a way that focusses more on the challenges of Dutch Studies in a 21st century society’. What does this entail and what was the approach? Esther Op de Beek, university…
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Faculty D&I training: 'You're never too old to learn this'
A variety of Diversity & Inclusion training courses are offered at faculty level on topics such as prejudice, diversity in the workplace and inclusive education. During these courses, participants have the opportunity to talk about their experiences.
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Tom Kouwenhoven wants to develop a bridge between AI and humans
It is a familiar phenomenon: you ask the assistant on your phone to call your mother, but it calls a friend instead. Tom Kouwenhoven, PhD student in the SAILS programme, investigates how humans and Artificial Intelligence (AI) can better communicate with each other, so that these kinds of situations…
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Jasper's Day
On January 1st Jasper Knoester started as our new dean. How is he finding it? What kinds of things is he doing and what does his day look like? In each newsletter, Jasper gives a peek into his life as dean.
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Overarching PhD lab on Leiden PhD projects regarding Institutions for Conflict Resolution
On 21 June 2021 a meeting took place during which PhD candidates within the research theme 'Institutions for Conflict Resolution' at Leiden University presented the current state of their doctoral research.
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Four Leiden Scientists: 'Environmental risks of new pesticides with nanoparticles insufficiently examined'
The environmental risks of new pesticides containing nanoparticles are inadequately researched, according to four Leiden scientists in the scientific journal Environmental Science & Technology. They call for an examination of the long-term and environmental effects of pesticides containing nanoparti…
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Stephan Raaijmakers: ‘Everyone within Humanities can contribute to the study of AI’
Stephan Raaijmakers has been Professor of Communicative AI since 1 May. Prior to this, he had held this position for five years as professor by special appointment. How has his approach to AI changed in that time?
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Jasper's day
On January 1st Jasper Knoester started as our new dean. How is he finding it? What kinds of things is he doing and what does his day look like? In each newsletter Jasper gives a peek into his life as dean.
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Breakthrough artificial photosynthesis comes closer
Imagine we could do what green plants can do: photosynthesis. Then we could satisfy our enormous energy needs with deep-green hydrogen and climate-neutral biodiesel. Scientists have been working on this for decades. Chemist Chengyu Liu will receive his doctorate on 8 June for yet another step that brings…
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'Level Up' to reconnect European society for a higher level of democracy
Level Up is a non-profit project led by a multi-disciplinary team of doctoral researchers in the framework of the Europaeum Network was founded by the University of Oxford University. Sophie Veriter explains the importance of Level Up, the development of the ‘Level Up Toolkit’, and why this project…
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Dual PhD Centre
December marks the 15th anniversary of the Dual PhD Centre (DPC). Director Johannes Tromp and associate professor Mark Dechesne look back and ahead. Dechesne: ‘The DPC forms a 'community of knowledge' in which science and society are connected.’
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Child rights expert sounds the alarm: ‘Global crises are hitting children hardest’
Wars, climate change and the effects of covid have caused a global decline in children’s well-being. In her inaugural lecture Ann Skelton, Professor of Children’s Rights in a Sustainable World, points to the disastrous effects of multiple interacting crises.
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Introducing: Rafal Matuszewski
Rafal Matuszewski is an assistant professor at the Institute for History since 1 August 2023. Below he introduces himself.
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Actively working with the teaching material in the classroom
How do you get more interaction with your students during class? Paz Gonzalez has devised a method by which she gives her students an active role during class, turning (even large-scale) lectures into a seminar.
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How Dutch houses can become almost energy- and CO2-neutral
How much energy and greenhouse gas emissions can Dutch homes save? Xining Yang uses Leiden as an example and shows with his research how enormous the impact can be. At least, if we work harder on becoming more sustainable. Based on the models he developed, Yang will receive his doctorate on 28 June.
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'I don't want that benefit anymore': Why people aren't claiming the financial support they're entitled to
Fear of repayment demands is causing people to forgo benefits and financial support, even when they are eligible. This was one of the finding of Olaf Simonse in his PhD research on financial stress and the non-use of social services. His proposal: 'Let the government take the initiative.'
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The Netherlands and China work together to improve their wastewater management
Netherlands and China can learn from each other to handle household and livestock wastewater more sensibly. In the FOREWARD project, scientists from Leiden, Wageningen, and China are working together with local partners on feasible solutions that advance the environment, health, and economy.
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eLaw engages the European robotics community in shaping the future of robot regulation
As part of the LIAISON Research Project, Eduard Fosch-Villaronga and Hadassah Drukarch organised a workshop at the European Robotics Forum (ERF 2021) to engage the broader community in the projects’ goal of liaising robot development and policymaking.
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Finding the origin of giant black holes
‘Space Antenna LISA will open an unprecedented window on the Universe,’ says astronomer Elena Maria Rossi. The mission will be the first one to detect Gravitational Waves from space. These can tell us more about the beginning of our Universe and the formation of black holes. With an NWO grant of twelve…
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Dutch Cancer Society allocates funds to a mathematician: for treating Ewing sarcoma with the help of an app
If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…
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Oekraïne conferentie 75 universele verklaring v
Universele Verklaring voor de Rechten van de Mens en het Genocide verdrag, 75 jaar Oekraine
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Green roofs and tile flipping: research in The Hague on the best approach to climate and species diversity
Does a communal garden provide cool air and warm neighbourly relations? Does an additional row of trees increase biodiversity? These kinds of questions are key in the COMBINED project, on which Leiden scientists and residents of The Hague, among others, can work for six years with 4 million euros from…
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A government that works with citizens brings hope, but also many dilemmas
Anthropologist Anouk de Koning about the tottering welfare state and the dilemmas of a government operating as a nearby, friendly partner.
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Cycling like a Jumbo-Visma pro with the Leiden data model
Just like the professional riders from the Jumbo-Visma team, amateur cyclists will soon be able to analyse and improve their performance. Leiden data scientists working with the cycling team are making their smart data model available so that every serious cyclist can keep track of their fitness.
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Word from the LUCSoR Chair: September 2024
Welcome to the 2024-2025 academic year! I hope this finds you feeling refreshed following an enjoyable and restful summer holiday season. As we start the autumn semester, I want to look back briefly by highlighting 10 significant milestones at LUCSoR from this past year (some of which I referenced in…
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Márton Biró: ‘My only condition was going on exchange to Leiden’
He studied Dutch Studies, did Dutch literature research for his internship, and worked at HEMA: Hungarian Márton Biró (26) came to the Netherlands on exchange and decided to stay.
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Students build software for real customers
Students gain practical experience while clients receive a solution to their software needs: the student software company LUdev hits two birds with one stone. ‘Through LUdev, students learn what else is involved in software development besides programming.’ Interested? You can now submit new projects…
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‘Science is always the foundation for finding the best treatment, but we should broaden our scope'
As of 1 August, Anika Bexkens has been appointed Professor of Evidence-Based Clinical Practice for Child and Adolescent Mental Health. Her research focuses on the optimal application of scientific knowledge in practice. ‘Scientists and practitioners often speak past each other.’
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Tirong Guo discovered materials that bring efficient artificial photosynthesis closer
After hard work in the lab, Chemist Tirong Guo has developed a group of materials that provide a stable and efficient foundation for artificial photosynthesis. Will this enable the large-scale production of hydrogen and other useful compounds in the most sustainable way possible? Guo will defend her…
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'Elections are in the air here in Brussels, the energy is surreal'
German-American Mia Müller (26) has been working at the European Parliament for three years now as Press Officer at The Greens/EFA Group. She is a bit nervous about her 'first' elections.
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More housing in cities is possible without sacrificing green spaces
Building more in urban areas is, in most places in the Netherlands, the smartest way to tackle the housing crisis. This is evident from research conducted by Janneke van Oorschot, published in a partner journal of Nature. Remarkably, this does not have to come at the expense of green spaces in cities.…
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European subsidy for Ellen de Bruijn: ‘Hormonal fluctuations in women have been ignored for too long in brain research’
Psychologist Ellen de Bruijn studies the effects of hormonal fluctuations on behaviour and on the brain over a woman's life course. With an ERC Consolidator grant, she and 3 PhDs and a postdoc will further her EEG research on the different stages at which girls and women experience strong hormonal f…
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Architect Aleida Nijland: ‘The building will become greener in many ways’
Now that the Herta Mohr building is fully operational, construction work is moving to the other side of the University Library. Over the coming years, the former Matthias de Vrieshof will be transformed into the Aleida Nijland building. Architect Bart van Kampen tells us more about the plans.
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‘Teaching is like a professional sport: you always have to be switched on’
For a long time, Thijs Bosker was an average student, until he discovered how exciting learning becomes when there are no ready-made answers. To his students, he passes on one key message: hope is the driving force that keeps us moving forward. They nominated him as Lecturer of the Year.