326 search results for “target therapy” in the Staff website
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‘Build resilience in traumatised children and young people’
Many children experience trauma and if they are unable to deal with it properly, it can have a huge personal and societal effect. Building resilience in vulnerable children and young people should therefore have the highest priority. This is the message of Anne-Laura van Harmelen, Professor of Brain,…
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Stimulating the gut–brain nerve can influence emotion
Stimulating the vagus nerve, which provides a direct link between the gut and brain, makes people pay less attention to sad facial expressions. This research study by psychologists Katerina Johnson and Laura Steenbergen is published in the journal Neuroscience.
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Research and current affairs: 2022 in six stories
Life returned to something resembling normal after Covid but other crises soon took its place. These great challenges are also being felt at the University and our researchers are working on solutions. The nitrogen crisis, problems with young people’s services and an increasingly urgent climate crisis:…
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1K Z1E j3 bench in Huygens building should inspire people to listen to each other about how things are really going
A 1K Z1E j3 bench has been in the Huygens building since Thursday. The bench symbolises making suicide, depression and despair negotiable. 'We hope this bench invites people to start the conversation about how they are really doing,' says student wellbeing officer Elly van Laar. 'But it all starts with…
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Parental criticism hurts: a glimpse inside the adolescent brain
It may seem as though adolescents do as they please, but they are more sensitive to their parents’ opinions than they would appear. The adolescent brain reacts strongly to parental criticism or praise. These are the results of a study by an interdisciplinary research group of psychologists and neuroscientists…
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Four NWO Open Competition grants for Leiden researchers
Four researchers from Leiden University have been awarded NWO Open Competition grants in the Science domain. This is for research into subjects such as immune cells in tumours, antibiotic resistance and magnetic semiconductors.
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Podcast: Social Anxiety Disorder
Have you ever experienced the feeling of awkwardness when attending a party where you didn’t know anybody? Ever felt shy at a party within the first few minutes? While this feeling is labelled loosely as feeling socially anxious, social anxiety disorder goes to a much further extent.
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Seeking new concepts to treat diseases
Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’
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Over a million euros for two studies on solutions to antimicrobial resistance
Two consortia led by Leiden researchers have been awarded over one million euros by the Dutch Research Council and the Ministry of Health, Welfare and Sport to find solutions to antimicrobial resistance.
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Werken aan een effectiever malariavaccin
In het Leids Universitair Medisch Centrum wordt gewerkt aan de ontwikkeling van een nieuw malariavaccin dat effectiever is dan de huidige vaccins.
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Sabine van der Asdonk wins Gratama Science Prize 2021
For her research into complex family problems, an assistant professor in Forensic Family and Youth Care Studies Sabine van der Asdonk has won the Gratama Science Prize 2021, a prize for talented young researchers from the universities of Leiden and Groningen. The jury praised Van der Asdonk’s excellent…
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Silver and light: a powerful combination with the potential to save lives
Packages of DNA strands containing silver, measuring just two or three nanometres in size. Leiden physicists Donny de Bruin and Dirk Bouwmeester create these packages, which can enter living cells on their own. They then activate the silver with light, causing the cells to break down. This could, in…
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Zware metalen hebben slechte reputatie, maar genezen ook kanker
Veel mensen denken dat zware metalen giftig zijn en mens en natuur altijd schade aanbrengen. Dat beeld moet genuanceerd worden, vindt hoogleraar Sylvestre Bonnet.
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Thirteen NWO Open Competition XS grants for Leiden researchers
From medicines from snake venom to supercrops and the origin of words. Thirteen researchers from Leiden University will receive Open Competition XS grants from the Dutch Research Council (NWO).
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Burnout First-aid Kit
Personal development, Working effectively
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From stress to success; How actinobacteria exploit live without a cell wall
PhD defence
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Celebrating 40 Years of Bio-Pharmaceutical Sciences
During our special Fall symposium on November 28, we celebrated the 40th anniversary of Bio-Pharmaceutical Sciences. Organized in collaboration with our study association L.P.S.V. „Aesculapius”, the event brought together staff, students, and alumni for an afternoon focused on four decades of ‘Innovation…
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‘At first I didn’t understand anything, now I can explain it’
Engineering, law, and business students came together in the LDE Space & Society Honours Programme to explore how space and society can mutually benefit each other. At the final event, they looked back upon a steep learning curve. ‘We tossed them into the water and they had to swim.’
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Psychologists at Lowlands Science: can virtual reality trigger a psychedelic experience?
Fantastic plants, dizzying patterns and pulsating sounds: researchers from Leiden are going to study the effects of a simulated psychedelic trip on the mind and body at Lowlands Festival. Why might this be interesting for therapies?
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Nutrition and fasting for the brain: why the Keto diet shows promise
Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.
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'It’s the complexity of this group of patients that makes the challenge of improving their quality of life so interesting’
Dialysis patients experience a range of physical and mental symptoms that interact and influence each otherIn her doctoral research, psychologist Judith Tommel wanted to find the optimum approach to help these dialysis patients improve their quality of life. ‘We need to make sure we avoid excluding…
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Life after the Grand Jamboree: Wrapping-up iGEM
‘A challenging rollercoaster, but also a very bonding and insightful experience,’ that’s how the team of iGEM Leiden 2022 wraps up their participation in the iGEM contest. The contest for synthetic biology climaxed during the Grand Jamboree in Paris. The team ended up in the top 10 of over 360 teams…
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Biological Origami at molecular level: folding a single protein
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…
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Atherosclerosis resembles an autoimmune disease. Marie Depuydt graduated on this topic, with honours
In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…
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Leiden students build smart antibodies with protein 'Velcro'
Nine students dove into a challenging iGEM project this summer. With their idea, they aim to make antibodies more efficient - and in the meantime learn at least as much about collaboration, creativity and their own future.
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Man-made antibodies may change the future of drug development – here’s why
Sometimes an idea seems so logical and elegant at first glance, that you later wonder why no one thought of it before. Two researchers from LACDR have teamed up to develop a completely synthetic alternative to antibodies—one that mimics their size, shape and function, but which is cheaper, more stable,…
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Alumnus Anne Speckens opened a mindfulness centre in Nijmegen
Professor of Psychiatry Anne Speckens studied medicine in Leiden and did her psychiatry training there too. She opened the Radboudumc Center for Mindfulness in Nijmegen. What does she do there and how does she look back on her time as a student?
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In memoriam: Andrea Evers (1967 - 2025)
It is with deep sorrow that we share the news that our dear colleague Andrea Evers passed away on Monday, 4 August 2025. Since 2013, Andrea had been affiliated with the Faculty of Social and Behavioural Sciences at Leiden University as Professor of Health Psychology. She was an undeniable driving force…
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Medical Delta professor Ariane Briegel: 'I love working with people from different backgrounds'
Multidrug-resistant pathogens and worldwide pandemics are increasing, making infectious diseases more prevalent. To develop new treatments, deeper knowledge of the interaction between bacteria and human cells is required. Ariane Briegel recently became a Medical Delta professor and studies such path…
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It is not easy to simplify your research
Defending your PhD research in front of nearly 300 elementary school students: that was the challenge faced by PhD candidates Jo-Anne Verschoor and Marinka de Willigen during the VUURVLIEGEN competition organised by the Centrum JongerenCommunicatie Chemie (C3). After an exciting competition, the children…
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‘Children’s healthcare rights deserve more attention’
‘Children’s rights are somewhat of a poor relation’, says Professor of Law and Health Mirjam Sombroek-van Doorm. In her inaugural lecture, she will emphasise how more attention needs to be paid to children’s rights in current thinking on law and health.
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De nieuwste onderzoeken in kaart op de publieksdag Brein & Recht
How does our brain interpret traces of evidence? Can someone who is suffering from brain damage be held accountable for criminal offences? And should it be possible to adjust a criminal’s behaviour with deep brain stimulation? These questions were addressed during the Public Scientific Day Brein & Recht…
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Fear and silence at Lowlands: Festival visitors take part in Leiden research
Last week’s sunny Lowlands festival was not just an occasion for partying and dancing. Visitors were also given a glimpse – as test volunteers – into scientific research. How do you conduct research on fear and silent communication at a festival?
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Leideners and researchers learn from each other at the Science Market
3 October University has become something of a tradition: a bit of science among the Leidens Ontzet celebrations. During the new and improved edition, the WetenschapsWarenMarkt (Science Market), visitors spoke to researchers about the nitrogen problem, making organs and the city’s connections with A…
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Dutch Cancer Society allocates funds to a mathematician: for treating Ewing sarcoma with the help of an app
If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…
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Contributing to cancer research in your own way: three PhD candidates on their work within Oncode Accelerator
Accelerating the development of new cancer medicines by joining forces—that’s the mission of Oncode Accelerator, a Dutch consortium that recently welcomed three Leiden-based PhD candidates. Under the guidance of Gerard van Westen, Marc Boef, Remco van den Broek, and Lucina-May Nollen are exploring how…
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Make your research project visible in no time
A webpage for your research project can help with participant recruitment and foster collaboration with fellow researchers or social partners. Creating such a page used to be a time-consuming task, but with the help of AI, the communications team can now build a clear project page much more quickly.
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With 30 million dollars, this consortium aims to tackle tuberculosis
Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…
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Perspective for people with borderline personality disorder
‘Raising awareness of the disorder is crucial since borderline personality disorder (BPD) still faces considerable stigma ’, says Anne Krause-Utz (Clinical Psychology) . Together with an international team of excellent scientists, Krause-Utz provides an update of current knowledge about this disorder,…
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Nerve stimulation effective in patients with untreatable cluster headaches
Extremely painful chronic cluster headaches – sometimes referred to as ‘suicide headaches’ – can be prevented by stimulating the occipital nerve in the back of the head, according to research conducted by Professor Emeritus of Neurology Michel Ferrari from Leiden University Medical Center (LUMC). The…
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Geef ouders en kinderen een stem en vergroot de kans dat kinderen weer thuis worden geplaatst
Het Leids onderzoek naar gedwongen uithuisplaatsingen van kinderen heeft veel stof doen opwaaien. Op een congres bespraken meer dan 250 mensen het onderzoek verder om zo de situatie voor ouders en kinderen in de toekomst te verbeteren.
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Depressed adolescents gain little benefit from eye contact with their parents (although connection is so very important)
Eye contact between parents and children improves their mood and increases feelings of connectedness on both sides; but not in the case of depressed adolescents, Mirjam Wever discovered. Where the parent-child bond has been disrupted, it can be strengthened not only with therapy for the child but also…
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What works in suicide prevention? Lessons from the 113 Helpline
113 Suicide Prevention gave a guest lecture about suicide prevention at the Spanish Steps in Wijnhaven
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New SPARXS technique reveals DNA behaviour at unprecedented speed
Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…
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Eight professors receive double appointment simultaneously
Delft, Nov. 15th, 2022 – Today, eight professors were simultaneously inaugurated as ‘Medical Delta professors’ at Leiden University, LUMC, TU Delft, Erasmus University and/or Erasmus MC. With an appointment of two or more of these five academic institutions, they combine technology and healthcare in…
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Combating antibiotic resistance together
Antibiotic resistance is a common problem among patients. The European Project TIPAT trains pharmacologists, microbiologists and immunologists of six universities in interdisciplinary thinking. The ultimate goal is to develop better treatment guidelines to combat resistance. Coen van Hasselt of the…
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A tail with a twist: how the tokay gecko grows a completely new body part
When the tokay gecko loses its tail, a new one grows from resident stem cells at the stump. Each tissue type - muscle, bone, blood vessels and skin - develops from specific stem cells. This discovery by Luthfi Nurhidayat holds potential implications for advancing regenerative medicine in humans. Nurhidayat…
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700,000 euros for the fight against aggressive breast cancer
To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…
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European subsidy for Ellen de Bruijn: ‘Hormonal fluctuations in women have been ignored for too long in brain research’
Psychologist Ellen de Bruijn studies the effects of hormonal fluctuations on behaviour and on the brain over a woman's life course. With an ERC Consolidator grant, she and 3 PhDs and a postdoc will further her EEG research on the different stages at which girls and women experience strong hormonal f…
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Report: key role for Leiden in Dutch earning capacity
Leiden University and the Leiden Bio Science Park can make a significant contribution to the earning capacity of the Netherlands. This is the finding of the National Investment Agenda presented today.