282 search results for “bioactive molecular” in the Staff website
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Chemistry as the key to medical innovation
Is it a coincidence that three chemists from the same department have each independently received a ZonMw grant? 'No,' the researchers agree in unison. 'The role of chemistry in medical biology is becoming increasingly important, and we’ve worked hard to make this happen.'
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LACDR-Bruker Bio-AFM workshop: connecting disciplines through force spectroscopy
On the 6th and 7th of September 2023, the Leiden Academic Centre for Drug Research (LACDR) organized the Leiden Bio-AFM workshop in cooperation with Bruker Nano GmbH (Germany) and Bruker Nederland BV. The organization of this event was led by the Medical Systems Biophysics and Bioengineering group (Alireza…
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Rob Schilperoort Memorial unveiled at Leiden Bio Science Park
The Rob Schilperoort Memorial will be unveiled at the Leiden Bio Science Park on Saturday 16 September. This gigantic gate stands at the entrance to the park, which is also named after Schilperoort, its founder.
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Mesmerising images from James Webb space telescope
The 'deepest and sharpest' image of the Universe to date: the first photos from the new James Webb space telescope yesterday mesmerised astronomers and the public alike. Leiden Professor of Molecular Astrophysics, Ewine van Dishoeck, spoke to various media outlets about the first images, which include…
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Marco van Eijk new OD of Life Science & Technology
As of 1 September, Marco van Eijk has been appointed Director of Education of the bachelor's programme Life Science & Technology. He succeeds Marcellus Ubbink, who moved to the position of Scientific Director of the Leiden Institute for Chemical Research (LIC). Van Eijk has been appointed for a period…
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In memoriam professor Jo Hermans
On Tuesday evening 22 August, our very dear colleague Jo Hermans passed away. Jo had been ill for some time, but continued to enjoy life in good spirits until the very end. He meant a great deal to Leiden University and will be remembered with fond memories by many.
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Young Hae ChoiFaculty of Science
y.h.choi@biology.leidenuniv.nl | +31 71 527 4510
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Sculptures provide more diverse view of University’s history
Three new initiatives will provide a more diverse view of Leiden’s academic history, literally and figuratively: a historical study on the background of students and scientists, a new book about the Academy Building, and two new sculptures of female scientists, Ewine van Dishoek, Professor of Molecular…
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Foraging skills may have made the essential difference in the evolution of our huge brain
Hunter-gatherers acquire their food through complex gender-specific foraging techniques for a relatively stable and diverse supply of energy. New research indicates that this specialisation by boys and girls starts at a very young age. Most likely, this enabled the human species to evolve much larger…
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‘Look beyond your own discipline’
Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.
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First detailed picture of ice in planet-forming disk
An international team of astronomers led by Ardjan Sturm of the Observatory has made the first two-dimensional inventory of ice in a planet-forming disk of dust and gas surrounding a young star. The researches, including Melissa McClure, used the James Webb Space Telescope and publish their findings…
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Versatile antiviral proteins discovered with supercomputer
A single tiny molecule that can destroy flu, corona, HIV and Zika viruses? Yes, it really does exist. Biophysicist Niek van Hilten, who will receive his doctorate on 14 September, contributed to this discovery.
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Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
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LACDR PhD-Postdoc event - 12 October 2022
On October 12th, the LACDR PhD-Postdoc event will be organized in castle Oud Poelgeest.
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Renske Donkers wins Young Star Award, students surprise lecturers
Molecular Science & Technology student Renske Donkers has won the second edition of the Young Star Award. During the ceremony on Wednesday 17 February, no less than three teachers were awarded the title 'Teacher of the Year'. Finally, students had a surprise in store for all teachers: with a video they…
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Oncode Accelerator funds preclinical development of cancer therapies
Through its Demonstrator Projects, the Dutch Oncode Accelerator consortium provides grants for preclinical cancer therapy development. The first call for these projects is open until September 2025.
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From Leiden to Harvard: four questions for Julia Santos
Eight early-career researchers from around the world have been awarded a 51 Pegasi b Fellowship – a prestigious opportunity for astronomers. Julia Santos, a PhD candidate at Leiden Observatory, is one of them. We asked her four questions about this remarkable fellowship.
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Wood formation further explored by NWO-XL grant
Leiden researchers, Professor Remko Offringa and co-applicants Salma Balazadeh and Frederic Lens received an NWO-XL grant (2.5 million euros). Together with researchers in Wageningen and Groningen, they will study the genetic and environmental drivers of woodiness. From plant to molecule, the groups…
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Countering nerve pain caused by chemotherapy with new drug
Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…
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National Growth Fund invests many millions in faster and more sustainable (cancer) drug development
On 14 April, the National Growth Fund awarded million euros in grants to two consortia in which Leiden's science faculty is involved. Pharma-NL will receive 80 million euros and Oncode-PACT 325 million euros. Pharma-NL wants to make medicines available to the patient faster and more sustainably. Oncode-PACT…
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Joke Bouwstra is the first woman to receive the Dr Saal van Zwanenberg Honorary Prize: 'Wonderful to be in a line of distinguished scientists'
Emeritus professor Joke Bouwstra (LACDR) will receive this year's Dr Saal van Zwanenberg Ereprijs: a tribute to her years of fundamental research on the skin and the transport of drugs through the skin. This is the first time the prize has gone to a woman.
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The hunt for nanoplastics is on
How do you count the nanoplastics in your body? Leiden researchers published a method in Nature Protocols today that should make this easier. Important for both environmental and medicine research.
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Somayah ElsayedFaculty of Science
s.elsayed@biology.leidenuniv.nl | +31 71 527 4561
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Mario van der SteltFaculty of Science
m.van.der.stelt@chem.leidenuniv.nl | +31 71 527 4768
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Remus DameFaculty of Science
rtdame@chem.leidenuniv.nl | +31 71 527 5605
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Fourteen Leiden University researchers receive Vidi grant
The Dutch Research Council (NWO) has awarded Vidi grants to 14 Leiden researchers. This grant of a maximum of 850,000 euros will enable them to start a new research group and develop their own line of research over the next five years.
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How Oncode-PACT is bringing new cancer medicines closer with 325 million in Growth Fund money
How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…
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Why biology students and teachers value the E-learning skills platform
Students of the Biology minor course Molecular Design have successfully boosted their skills in collaboration, research and writing with the recently developed E-learning Skills Platform. The biology students and their teachers greatly value the initiative. ‘Sometimes I couldn’t believe what progress…
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Plastics are causing stress to crops (and biodegradable alternatives do too)
Micro- and nanoplastics cause stress to crops such as lettuce and carrots, PhD candidate Laura Julia Zantis found. This can lead to reduced growth and a lower nutritional value. Biodegradable plastics have this effect too, likely because of chemicals they release during degradation.
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Post-lockdown ceremonies: corona-proof but festive nonetheless
After the lockdown, it was again possible to receive graduates and guests at the University. In recent weeks, BSc and MSc graduates from various study programmes were festively awarded their diplomas in a special corona-proof setting in the restaurant of the Gorlaeus Lecture Halls building. This resulted…
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Sabine van der Asdonk wins Gratama Science Prize 2021
For her research into complex family problems, an assistant professor in Forensic Family and Youth Care Studies Sabine van der Asdonk has won the Gratama Science Prize 2021, a prize for talented young researchers from the universities of Leiden and Groningen. The jury praised Van der Asdonk’s excellent…
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How a bachelor’s student contributed to better chemical simulations
Doğukan Yilmaz chose a study that aligned with his favourite subjects, and it paid off. For his bachelor thesis, he developed a new model to better predict an important chemical reaction. ‘On the edge of what is possible at the bachelor level,’ his supervisors write. Thanks to his impressive achievements,…
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Running Leiden Marathon in a 450th-anniversary t-shirt
Nearly 19,000 runners lined up at the start of Leiden Marathon on Sunday, among them students and staff from the university. For some this was their first race, for others a highlight of their year. This year, in celebration of our 450th anniversary, they ran in a special jubilee t-shirt.
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New research at the Hortus: the delimitation of the genus Uvaria L.
In the tropical rainforests of Southeast Asia the soursop family (Annonaceae) can be found. The genus Uvaria is a part of this family, but it has not yet been described entirely correctly. That is what Annas Rabbani will be studying during the next four years as a PhD student at the Hortus botanicus…
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AI model accurately predicts endometrial cancer recurrence
Researchers from the Leiden University Medical Center (LUMC) have developed an AI model that accurately predicts the risk of endometrial cancer recurrence.
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Inspired teaching without the administrative hassle
In his inaugural lecture Dennis Claessen will explain how he wants to ensure that lecturers have less admin to do.
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A ‘lock’ to make genetic modification safer
Genetically modified organisms (GMOs) could be useful allies in the fight against critical environmental problems. Could because the use of GMOs is strictly regulated at the moment. A Leiden student team is now trying to make these GMOs safer with the aid of an ingenious lock.
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Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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Three innovative research projects awarded Open Competition Science-M funding
Tracking mucus-eating bacteria, mapping the complexity of planetary nebulae and a signalling pathway in cancer. These three Leiden projects have been awarded Open Competition Science-M funding by the Dutch Research Council.
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‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
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Leiden-developed drug candidate ready for final clinical trial phase
Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.
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Recent PhD defenses
Here we highlight the achievements of our latest PhD graduates, each of whom has made significant contributions to the advancement of the field of (bio)pharmaceutical sciences.
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Treatment before patients develop rheumatism provides lasting relief
Early treatment benefits patients who have not fully developed rheumatoid arthritis but are in the preliminary stages of the disease. This is what researchers from the Leiden University Medical Centre (LUMC) have reported in The Lancet. Patients in the pre-arthritis stage who were temporarily prescribed…
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Planet-forming discs around young low-mass star differs fundamentally from one around sun-like star
Using the James Webb Space Telescope, an international team of researchers, including Leiden Professor of Molecular Astrophysics Ewine van Dishoeck, has discovered a palette of hydrocarbons in a planet-forming disc around a young, low-mass star. The results confirm that discs around very lightweight…
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Help your students: offer extra support with the skills platform
A new course is often challenging enough for students. But in addition to the new subject matter, they also face all kinds of additional challenges: how do I write a report, how do I find reliable sources, or how do I pitch a research proposal? The e-learning skills platform offers an online learning…
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Leiden University Global Fund grants 14 project proposals
On 9 December, a lottery to conclude the first call of the Leiden University Global Fund (LUGF) Seed Fund has granted 14 project proposals €15.000. These projects will be working to enhance the relationship between Leiden University and her partners in Africa, Latin America, North East and South East…
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Over a million euros for two studies on solutions to antimicrobial resistance
Two consortia led by Leiden researchers have been awarded over one million euros by the Dutch Research Council and the Ministry of Health, Welfare and Sport to find solutions to antimicrobial resistance.
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First MIRI-image by the James Webb Space Telescope
The alignment of the James Webb Space Telescope is complete. The space observatory is able to capture sharp, well-directed images with each of its four powerful scientific instruments on board. The MIRI instrument, on which Professor of Molecular Astrophysics Ewine van Dishoeck also worked, was the…
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Leiden researchers join forces against tuberculosis
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…