282 search results for “bioactive molecular” in the Staff website
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AI model accurately predicts endometrial cancer recurrence
Researchers from the Leiden University Medical Center (LUMC) have developed an AI model that accurately predicts the risk of endometrial cancer recurrence.
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New research at the Hortus: the delimitation of the genus Uvaria L.
In the tropical rainforests of Southeast Asia the soursop family (Annonaceae) can be found. The genus Uvaria is a part of this family, but it has not yet been described entirely correctly. That is what Annas Rabbani will be studying during the next four years as a PhD student at the Hortus botanicus…
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Sabine van der Asdonk wins Gratama Science Prize 2021
For her research into complex family problems, an assistant professor in Forensic Family and Youth Care Studies Sabine van der Asdonk has won the Gratama Science Prize 2021, a prize for talented young researchers from the universities of Leiden and Groningen. The jury praised Van der Asdonk’s excellent…
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Plastics are causing stress to crops (and biodegradable alternatives do too)
Micro- and nanoplastics cause stress to crops such as lettuce and carrots, PhD candidate Laura Julia Zantis found. This can lead to reduced growth and a lower nutritional value. Biodegradable plastics have this effect too, likely because of chemicals they release during degradation.
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Inspired teaching without the administrative hassle
In his inaugural lecture Dennis Claessen will explain how he wants to ensure that lecturers have less admin to do.
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Running Leiden Marathon in a 450th-anniversary t-shirt
Nearly 19,000 runners lined up at the start of Leiden Marathon on Sunday, among them students and staff from the university. For some this was their first race, for others a highlight of their year. This year, in celebration of our 450th anniversary, they ran in a special jubilee t-shirt.
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Three innovative research projects awarded Open Competition Science-M funding
Tracking mucus-eating bacteria, mapping the complexity of planetary nebulae and a signalling pathway in cancer. These three Leiden projects have been awarded Open Competition Science-M funding by the Dutch Research Council.
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Treatment before patients develop rheumatism provides lasting relief
Early treatment benefits patients who have not fully developed rheumatoid arthritis but are in the preliminary stages of the disease. This is what researchers from the Leiden University Medical Centre (LUMC) have reported in The Lancet. Patients in the pre-arthritis stage who were temporarily prescribed…
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Planet-forming discs around young low-mass star differs fundamentally from one around sun-like star
Using the James Webb Space Telescope, an international team of researchers, including Leiden Professor of Molecular Astrophysics Ewine van Dishoeck, has discovered a palette of hydrocarbons in a planet-forming disc around a young, low-mass star. The results confirm that discs around very lightweight…
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How a bachelor’s student contributed to better chemical simulations
Doğukan Yilmaz chose a study that aligned with his favourite subjects, and it paid off. For his bachelor thesis, he developed a new model to better predict an important chemical reaction. ‘On the edge of what is possible at the bachelor level,’ his supervisors write. Thanks to his impressive achievements,…
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Post-lockdown ceremonies: corona-proof but festive nonetheless
After the lockdown, it was again possible to receive graduates and guests at the University. In recent weeks, BSc and MSc graduates from various study programmes were festively awarded their diplomas in a special corona-proof setting in the restaurant of the Gorlaeus Lecture Halls building. This resulted…
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Leiden-developed drug candidate ready for final clinical trial phase
Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.
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Recent PhD defenses
Here we highlight the achievements of our latest PhD graduates, each of whom has made significant contributions to the advancement of the field of (bio)pharmaceutical sciences.
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‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
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Nathaniel MartinFaculty of Science
n.i.martin@biology.leidenuniv.nl | +31 71 527 2954
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Hermen OverkleeftFaculty of Science
h.s.overkleeft@chem.leidenuniv.nl | +31 71 527 5037
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In memoriam emeritus professor Jan Schmidt
On March 17, our dear colleague Jan Schmidt passed away after a fruitful and valuable life.
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Eight professors receive double appointment simultaneously
Delft, Nov. 15th, 2022 – Today, eight professors were simultaneously inaugurated as ‘Medical Delta professors’ at Leiden University, LUMC, TU Delft, Erasmus University and/or Erasmus MC. With an appointment of two or more of these five academic institutions, they combine technology and healthcare in…
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Contributing to cancer research in your own way: three PhD candidates on their work within Oncode Accelerator
Accelerating the development of new cancer medicines by joining forces—that’s the mission of Oncode Accelerator, a Dutch consortium that recently welcomed three Leiden-based PhD candidates. Under the guidance of Gerard van Westen, Marc Boef, Remco van den Broek, and Lucina-May Nollen are exploring how…
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Superselective bonds light up
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…
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A lifeline for Leiden research – TB solution a step closer thanks to this Indonesian university
Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…
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Tunnel vision alarm in the search for more efficient hydrogen cells
A tenacious postdoc researcher persuaded Professor Marc Koper to research the oxygen reduction reaction. In Koper's eyes, there was little of interest there. But they promptly discovered a whole new way to improve fuel cells on hydrogen and oxygen. Their article appeared in Nature Catalysis on 07 Ju…
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Jasper's Day
Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.
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Ewine van Dishoeck goes stargazing
From the birth of the universe to the molecules in a planet's atmosphere. The first five pictures from the James Webb Space Telescope (JWST) show the enormous range in which the space telescope can operate. Ewine van Dishoeck, professor of molecular astrophysics, took a look at the first images Tuesday…
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Webb detects icy ingredients for making potential habitable worlds
An international team of astronomers, led by Will Rocha of Leiden Observatory, using the NASA/ESA/CSA James Webb Space Telescope have discovered that the key ingredients for making potentially habitable worlds are present in early-stage protostars, where planets have not yet formed.
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Eredoctoraten voor Bonnie Honig, Eliot Higgins en Kelly Chibale
Leiden University will be conferring three honorary doctorates in its special anniversary year. They will be awarded to Eliot Higgins, truth finder and founder of Bellingcat, Bonnie Honig, expert in feminist theory and legal theory, and Kelly Chibale, professor of organic chemistry, who works on prevention…
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Robert Smit receives his PhD with distinction. ‘I am happy to be back in the lab’
An all-optical transistor, a molecule-sized sensor and a new kind of single-photon source for quantum communication. All dreamed applications of fundamental physics that are one step closer thanks to Robert Smit. On 12 June, he defended his PhD thesis with distinction.
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New SPARXS technique reveals DNA behaviour at unprecedented speed
Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…
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The Nobel Prize in Chemistry went to an AI model (and rightly so)
Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…
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Smart programming for the quantum computer that does not exist yet
Designing innovative algorithms, thinking outside the box, and brainstorming over coffee with his colleagues — this is what physicist Stefano Polla enjoys most. His success shines through in his nomination for the C.J. Kok Jury Award 2024 for PhD thesis of the Year.
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Frederic Lens: building bridges in biodiversity research
Four green research institutes in Leiden are joining forces to integrate evolution and biodiversity research, at local and at the national level. Pivot in this collaboration is Frederic Lens.
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Jasper's day
Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.
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Star birth: a slow and mysterious drama
A star does not just appear in the sky overnight. Its creation takes tens of thousands of years. Twenty years ago, astronomers took a picture of a star in its birth phase. The James Webb Space Telescope (JWST) could now capture that same star in much greater detail. This does not only provide beautiful…
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Room for everyone at a sun-drenched EL CID
Thousands of first-year students and hundreds of mentors kicked off the EL CID on Monday morning. This year for the first time, the introduction week of Leiden University and Leiden University of Applied Sciences was also open for students of Regional Training Centre mboRijnland and the Leiden Instrument…
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Gravitation funding for five projects with Leiden researchers
The Advanced Nano-electrochemistry Institute Of the Netherlands (ANION) consortium will receive 23.6m euros in Gravitation funding for research on important electrochemical processes for energy transition. An additional four consortia with members from Leiden have also been awarded funding.
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Astronomers spot benzene in planet-forming disk around star for first time
An international team of astronomers including Leiden professor Ewine van Dishoeck has observed the benzene molecule (C6H6) in a planet-forming disk around a young star for the first time. The observations tell us more about the forming of planets in this disc, like our own Earth. The scientists publish…
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ERC Starting Grants for five young Leiden researchers
Five researchers from Leiden University have been awarded a Starting Grant by the European Research Council (ERC). This grant of on average 1.5m euros enables researchers who show potential to start their own project, lead a research team and implement their best ideas.
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Medical Delta professor Marcel Reinders: ‘You need collaboration to make a real impact’
Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Vidi grants for eight researchers from Leiden University
Eight scientists from Leiden University have been awarded a grant by the Dutch Research Council (NWO). With this Vidi funding, the researchers can set up an innovative line of research and further expand their own research group over the next five years.
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‘Ultimately, the goal is to develop antibiotics for tuberculosis with a lower risk of resistance’
Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…
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LIFES: From Reusable Data to New Treatments and Faster Diagnoses
Early diagnosis, new treatments, and personalised care: all of these are possible if we can better unlock the wealth of information hidden in health data. Unfortunately, this data is often poorly organised, difficult to access, and not interoperable. The new international Leiden Institute for FAIR and…
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Physics in the picture: cancer cells as an explosion of fireworks
When you think of physics, do you think only of complicated formulas? You’re not the only one. Therefore, every year, the Leiden Insitute of Physics organises the LION Image Award to show another side of physics: beautiful images about intriguing science. The winner of the 2022 photo competition captured…
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Improving safety assessment of nanoparticles
How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…
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Biology brothers write book about nature and adventure in Eastern Europe: 'I didn't know there live pelicans in Romania'
With a self-converted red camper van, biologists and twin brothers Kevin and Marvin Groen go on a nature adventure in Eastern Europe. Together, they search for wild animals, beautiful nature and places to sport. From a long search for a bear in the Slovakian wilderness to the discovery that pelicans…
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More attention needs to be paid to prevention in the fight against cancer
On 11 November Professor of Gastroenterology and Hepatology, Monique van Leerdam will deliver her inaugural lecture entitled, ‘Aiming for Prevention’. Van Leerdam, who specialises in hereditary tumours, was appointed professor in July 2020. In her inaugural lecture she will discuss the importance of…
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Jasper's Day
On January 1st Jasper Knoester started as our new dean. How is he finding it? What kinds of things is he doing and what does his day look like? In each newsletter, Jasper gives a peek into his life as dean.
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Caught in living cells: how bacteria regulate their genes to defend themselves
For the first time, it was shown in living cells how the bacterium E. coli regulates genes that help it survive in a new environment. Biochemist Fatema Zahra Rashid managed to do this using a technique she fine-tuned. Her research into changes in 3-dimensional chromosome structure offers clues for ways…
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Jasper's Day
Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.
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Two young researchers win Krijn Rietveld Award for innovative research on blood donation and colorectal cancer
One used 3D cell models to study colorectal cancer, while the other used machine learning for more efficient blood donation. For these achievements, Marieke Vinkenoog and Simon Christian Hansmann were awarded the Krijn Rietveld Memorial Innovation Award on Tuesday 2 September.