What are the conditions under which coercive diplomacy can compel a State to abandon its nuclear weapons program?

Dynamic nuclear polarization with paramagnetic agents can enhance nuclear magnetic resonance signals by orders of magnitude. The mechanism of enhancement depends a.o. on the magnetic resonance properties of the agents used. Electron spin relaxation times at NMR relevant magnetic field/microwave frequencies,…

The researchers explore how instructional risk communication can support public safety during nuclear emergencies.

Linde Desmaele explores the role of US theatre nuclear weapons stationed in Europe. Moving beyond the deterrence vs. reassurance debate

Ice, the solid state of water, plays an important role on our planet as well as the entire universe.Despite the fact that an individual water molecule has a very simple structure, its chemical bonding in the solid phase can be surprisingly complex.

On 8 July 2020, Andres Sarmiento Lamus defended his thesis 'The Proliferation of Dissenting Opinions in International Law'. The doctoral research was supervised by Prof. L.J. van den Herik and Prof. Y.A.A.S. Radi (UCLouvain).

Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven

How does contemporary art and culture represent nuclear contamination in post-nuclear landscapes?

Promotor: T.H. Oosterkamp

What are the conditions under which coercive diplomacy can compel a State to abandon its controversial nuclear (weapons) program? Based on the experience of the US coercive diplomacy against the nuclear programs of three countries, namely Iran, Libya and South Africa, Jean Yves Ndzana’s PhD research…

Political scientists Huib Pellikaan and Niels van Willigen (Leiden University) use and elaborate on the theoretical insights from game theory in order to understand nuclear security in changing environment. Now that the relations between the US and Russia have deteriorated and smaller nuclear states…

Political scientist Nicolas Blarel (Leiden University) analsyses how non-state actors can (directly or directly) attempt to provoke conditions for a crisis between state actors that have nuclear capabilities. He argues that there is an urgent but complicated and understudied task to understand and manage…

Reducing greenhouse gas emissions is one of the most pressing challenges that humanity faces in the coming decades.

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

This open access volume surveys the state of the field to examine whether a fifth wave of deterrence theory is emerging. Bringing together insights from world-leading experts from three continents, the volume identifies the most pressing strategic challenges, frames theoretical concepts, and describes…

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Gold nanorods are biocompatible nanoparticles that present an excellent two-photon signal that can be used to get high spatial resolution inside living cells. Gold nanorods are photostable and therefore can be followed inside cells for long time, with possible applications as trackers in live cells.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

A lot of our research is performed at temperatures close to absolute zero, among other reasons because this increases the sensitivity of the measurements. 

Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.

Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…

This book provides the answers, presenting clear insights into the current state of affairs and exploring future prospects.

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

PhD defence

The Intelligence and Security research group focuses on intelligence and security within the European Union. Its approach is interdisciplinary and reflects ISGA’s broad perspective, combining insights from ethics, history, law, political science, psychology, and sociology.

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

An overview of the research at the Cancer Dug Target Discovery group.

X-Ray Diffraction (XRD), Nuclear Magnetic Resonance (NMR) and Cryo-electron microscopy (Cryo-EM) are the three main methods for solving structures of macromolecules.

Damien van Puyvelde and Fernando Tabárez Rienzi examine the evolution of Open-Source Intelligence (OSINT).

In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

This new article by Monica Kaminska is part of a special issue for Journal of Cybersecurity, based on a selection of contributions from THe Hague Program for Cyber Norms' 2019 Conference.

During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.

The central goal of academic publishers is the dissemination of the results of research and scholarship. Their audiences can generally be divided into two categories. Academic publications are firstly made accessible to the scholarly community, so that these texts can form the input for new academic…

On the occasion of prof Paul van der Heijden’s stepping down as Rector Magnificus and President of the Executive Board of Leiden University in 2013 the Chair bearing his name on Social Justice was established. It was a “farewell present” of the Leiden University to it’s Rector.