947 search results for “optimise drug design” in the Staff website
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Small actions by our labs add up to big steps in sustainability
Freezers set three degrees higher, a recycling bin for plastic petri dishes or timer switches installed on equipment: a growing number of Leiden University laboratories are taking small – but effective – steps to reduce their environmental impact, via the internationally recognized Laboratory Efficiency…
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LIFES: From Reusable Data to New Treatments and Faster Diagnoses
Early diagnosis, new treatments, and personalised care: all of these are possible if we can better unlock the wealth of information hidden in health data. Unfortunately, this data is often poorly organised, difficult to access, and not interoperable. The new international Leiden Institute for FAIR and…
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Ieke de Vries: 'We're expecting too much from minors and young adults if we think they can protect themselves from sexual exploitation.’
What starts off gently may end dramatically. Many young people these days fall victim to sexual exploitation. How can we prevent this suffering? Ieke de Vries points to the living environment of (potential) victims.
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Why North Korea and Southern Africa are dependent on each other
North Korea may seem like an isolated country but it has strong ties with African regimes. This alliance, which trades in arms despite international sanctions, is increasingly operating out of the liberal world order’s sight, PhD candidate Tycho van der Hoog warns.
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‘Ultimately, the goal is to develop antibiotics for tuberculosis with a lower risk of resistance’
Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…
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Rechtspraktijk in beeld
Woensdag 7 september bezochten de nieuwe eerstejaarsstudenten Rechtsgeleerdheid en Criminologie de Stadsgehoorzaal voor een College Tour met als thema: Strafzaken en de media. Presentatrice Annemarie Brüning, bekend van Hart van Nederland, ging hierover in gesprek met professionals uit het vakgebied…
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Better treatment of systemic autoimmune diseases requires close collaboration
Exceptional collaboration between physicians is needed to better understand and treat autoimmune diseases that cause inflammation in various organ systems.
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Room for everyone at a sun-drenched EL CID
Thousands of first-year students and hundreds of mentors kicked off the EL CID on Monday morning. This year for the first time, the introduction week of Leiden University and Leiden University of Applied Sciences was also open for students of Regional Training Centre mboRijnland and the Leiden Instrument…
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The person behind the murderer
Are all murderers calculating psychopaths with an obscene predilection for bloody chainsaws? Yes, if Hollywood is to be believed, but in the real world they are generally everyday people with problematic backgrounds. Professor of Violence and Interventions Marieke Liem therefore calls for the demythologisation…
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'Satisfied students give me more fulfillment than getting a research grant'
Imparting students with a critical attitude and cross-curricular skills. That is what Rawi Ramautar wants to strive for as the new programme director (OD) of the bachelor of Bio-Pharmaceutical Sciences. 'A programme director has to create a programme of which students say: I find it challenging and…
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‘Actively listening makes a difference but can be harder than removing a tumour’
As Professor of Translational Neuro-oncology, Marike Broekman researches how brain tumour treatment can be improved. She will discuss this in her inaugural lecture along with her work as a neurosurgeon and the importance of a positive workplace culture.
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Curing diseases with lab-grown organs
Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…
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Status update in the evolutionary race between humans and resistant bacteria: two steps forward for us
A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…
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Why is it now that the Left has momentum in Latin America (and how long it will last)
The left is gaining more and more ground on the political map of Latin America, with the elections in Colombia as the most recent example. But what’s behind this pull to the left? Professor of Modern Latin American History Patricio Silva talks about the current political situation in the region.
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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Organ failure caused by viruses, how does it work? Now there are methods to find out
Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…
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Join us at 3 October University and the Weekend of Science
Are you curious about how the human skeleton works? Discover this and more on 3 October in Leiden and on 4 October in The Hague.
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New traffic controller discovered on DNA railway
A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as a kind of ‘traffic controller’ on DNA. Without this protein, chaos ensues, potentially causing cancer. Their findings have been published in the prestigious journal Nature.
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Who takes the lead when no one is in charge?
Politie, gemeenten en sociale organisaties werken steeds vaker samen in netwerken om maatschappelijke problemen op te lossen. Samenwerking is noodzakelijk, maar ook complex. Zonder duidelijke leiders vraag dat om ander leiderschap. Voor haar proefschrift onderzocht Moniek Akerboom hoe leiderschap vormt…
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Antibiotic Conjugates and Natural Products as Next-Generation Strategies Against Antimicrobial Resistance
PhD defence
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New Year's Reception
Conference
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Blade Runner 2025?
Lecture, Studium Generale
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Beyond iced coffee and face masks: ‘True self-care is about emotional awareness and living according to your values’
In hun klinische stage leren Psychologiestudenten mentale steun bieden aan anderen, maar hoe zorgen zij als toekomstige therapeut ook voor zichzelf? Met video’s, podcasts en een panel wil Kelly Ziemer haar studenten de nodige zelfzorg-skills bijbrengen.
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Guilt and sentencing in the Netherlands: the impact of mental health reports
In one in four criminal cases in the Netherlands, the court receives a report on the state of the defendant’s mental health. How is that information used exactly and what are the consequences? Scientific research has been lacking in this area. The PhD research of Roosmarijn van Es is a first step in…
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‘It’s a great motivator if your research can be life-changing in the real world’
Our university labs are bursting with cutting-edge research, but how do you commercialise these inventions and discoveries or translate them into outcomes that benefit society? Professor of biological chemistry Nathaniel Martin started a spin-off company with his team. ‘When it comes to valorisation…
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Leiden Science rings in 2025 with inspiring speeches and happy winners
An impressive speech by Dean Jasper Knoester, a lecture by top researcher Mario van der Stelt about brain messengers, and the presentation of the faculty awards. 2025 begins on a hopeful and festive note, with a toast to a year of fruitful collaboration within and beyond the faculty.
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What makes our university strong and distinctive? Let your voice be heard!
What sets Leiden University apart from other universities? And what research themes would you like us to showcase to the outside world? Share your ideas in our online consultation over the next two weeks.
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‘Science is international so our faculty should be too’
‘Our faculty is a very international community. And that is something everybody really benefit from,’ says Yun Tian. As the officer internationalisation, she is the bridge between international students and staff, the faculty and universities abroad. ‘Science goes beyond countries and carries no nationality.…
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Problems arise when citizens request documents from public authorities with information on third parties
When Dutch citizens request information under the Open Government Act (Woo), third parties can ask the public authority to withhold certain information. Leiden research reveals that the position of these third parties is unclear and accessing information is a difficult process.
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How do we prepare students for jobs that don’t yet exist?
We can accrue pensions, reinforce dykes and make our homes more sustainable. But how do we make our higher education fit for the future? And what skills should we be teaching our students now for jobs that don’t yet exist? Lecturers and educational developers looked to the future during the keynote…
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Expanding Social Sciences & Humanities in African Global Health Discourse
LUNHA strives to redefine global health by prioritizing justice, fairness, and inclusion in Africa. Through collaboration with diverse stakeholders, LUNHA aims to reshape global health research and foster a broader engagement with social sciences and humanities.
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The Pursuit of Competence: Why our students need more meaningful challenges, not less.
The Leiden Academic Centre for Drug Research (LACDR) is closely connected to the education of our biopharmaceutical students, providing both courses and immersive internship projects. Among these is the Bachelor Research Project (BOO), which offers many students their first real scientific experience…
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Leiden University celebrates curiosity at 449th Dies Natalis
How has evolution shaped our curiosity? And how does that curiosity ensure that we now have the technological ability to discover whether we are alone in the universe? This was all covered during the celebration of Leiden University’s 449th Dies Natalis.
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‘Looking back, this past year will be a very important period in my life’
At the Faculty of Science, forty per cent of the employees are of a non-Dutch nationality. Amongst PhDs that is even sixty per cent. How are they doing in a time of working at home in a different culture, when travelling is not possible? Clinical pharmacologist Lu Chen is the third in this series to…
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How European blind spots strengthen the shadow order
As a strategy and international security specialist, Julien Bastrup-Birk (41) has advised both NATO and the United Nations Office on Drugs and Crime and worked at the UK Foreign and Defence ministries. Next week, he will defend his PhD on clandestine non-state power in the international system.
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Gilles van WezelFaculty of Science
g.wezel@biology.leidenuniv.nl | 071 5274310
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New dimensions of the cellular response to DNA damage
PhD defence
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Connect & FAIRify: FAIRification of a high throughput metabolomics laboratory with FAIR Digital Objects
Webinar, Q&A, discussion
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Getting personal: Advancing personalized oncology through computational analysis of membrane proteins
PhD defence
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Stronger together: the Leiden Research Support Network
The academic playing field is becoming more complex all the time, making a strong research support network crucial. Over 100 research support professionals shared knowledge, gained inspiration and became acquainted or got to know each other even better at the third Leiden Research Support Conference…
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Defence Minister at Ukraine Symposium: 'We Europeans have only one chance to get this right'
Three years on, and interest in Ukraine certainly hasn't waned. The auditorium at the Wijnhaven location was fully booked on Monday. Hundreds of people, including top military brass, listened to Defence Minister Brekelmans' speech. He pointed out to them: 'Here in the Netherlands, we're now living in…
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Diversity symposium 2021: small steps can increase inclusion
‘Culture change takes time,’ said Vice-Rector Hester Bijl at the closing panel of the University’s Diversity Symposium on 26 January. She talked about the road to a diverse and inclusive university. The symposium provided plenty of concrete examples of small steps that can already be taken.
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Leiden Law Cast: The prison population NL vs. BE with Miranda Boone
Leiden Law Cast is a podcast made by Leiden Law School, Leiden University, for everyone who wants to learn more about current legal issues.
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A promising marriage between Siemens and Leiden spin-off Culgi
Siemens recently took over the Leiden software company Culgi, founded by professor and inventor J.G.E.M. (Hans) Fraaije. We spoke to him about the algorithm that made him successful, the role of a university in our society and his ambitions at Siemens. ‘I was looking for Siemens, and they were looking…
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‘We couldn't really celebrate our vaccine being approved, but we were over the moon’
On 11 March, pharmaceutical company Janssen received approval to launch its corona vaccine on the European market. This made Janssen the fourth company to be given the green light by the European Medicines Agency. As Lead of the Janssen Campus in the Netherlands, Biology alumnus Bart van Zijll Langhout…
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Researchers from Leiden visit Indonesia on knowledge mission
A delegation from Leiden University recently embarked on a knowledge mission to various NGOs, universities and government organisations in Indonesia. New partnerships were formed and important knowledge exchanged, and researchers from Leiden gave guest lectures.
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Alumna Natacha Harlequin: ‘When it really matters, I’m a lion’
She stands out for the moderate tone she takes in discussions on Dutch talk shows. Without judgement you can have an open conversation, criminal lawyer Natacha Harlequin learned in her student days in Leiden. ‘What I personally think of the alleged act doesn’t matter so much.’