984 search results for “optimise drug design” in the Staff website
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Lina van DrunenFaculty of Social and Behavioural Sciences
l.van.drunen@fsw.leidenuniv.nl | 071 5272727
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Dirk VisserFaculteit der Rechtsgeleerdheid
d.j.g.visser@law.leidenuniv.nl | 071 5277888
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A future with tailored therapy for patients with atherosclerosis
The AtheroNeth consortium received €6 million from the Dutch Heart Foundation to gain a better understanding of the differences in disease progression among patients with atherosclerosis. The ultimate goal is to enable personalised treatment.
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Marije NiemeijerFaculty of Science
m.c.niemeijer@lacdr.leidenuniv.nl | 071 5276105
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Bas ter BraakFaculty of Science
s.j.ter.braak@lacdr.leidenuniv.nl | 071 5272727
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and Italian pharma company receive an EU grant to realise sustainable drug production
With a €1.5 million European grant, industrial ecologist Stefano Cucurachi will work on more sustainable production methods for the pharmaceutical industry. The Italian company Angelini Pharma intends to use the resulting knowledge to make its production process more sustainable.
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for effective application of a new revolutionary cholesterol lowering drug resides in a 30 year old Leiden Patent
‘’ And then the world changed forever ,welcome to the future’’. These are the words that Kausik Ray (President of the European Atherosclerosis Society) spoke when the worldwide first dose of inclisiran, a novel SiRNA based cholesterol lowering agent, was administered at the Cardiology lipid clinic at…
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Tools for a better work balance
The pages on the left of this screen offer valuable information, tips and strategies that you can use to optimise your work balance. After all, a healthy work balance not only improves your well-being, but also contributes to better professional performance.
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LACDR introduces ‘Digital Labcoat’ for Biopharmaceutical Sciences students
Learn to program, gain knowledge of AI methods, or use it in a research project at the LACDR. With the introduction of the innovative digital learning environment ‘Digital Labcoat’, Biopharmaceutical Sciences bachelor students can further develop their computational skills.
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MAGL modulators - Structure-guided optimisation and characterisation
Prof.dr. M. van der Stelt dr. A.P.A Janssen dr. R.J.B.H.N. van den Berg
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More control over your future with designing your future
The future does not yet exist, but many people think about it daily. The course Designing Your Future, part of the Honours Programme at the Faculty of Governance and Global Affairs and taught by Bram Hoonhout‘Being a mentor during HOP week is something I can recommend to everyone’
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BPS MSc course Design, Analysis, and Practical Use of Biologicals
BPS MSc student Guus Ruiter: This year I followed this new course called Design, Analysis, and Practical Use of Biologicals at the LUMC given by Rawi Ramautar and developed for both BPS MSc and Pharmacy students. During this course, there were many different speakers, in particular from biotech companies…
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Referral options
If you’re unsure where to refer students to for well-being support, this page should help. It provides an overview of the support available at Leiden University.
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A faster way to find new medicines – without the limitations of big DNA barcodes
Leiden researchers, led by Sebastian Pomplun developed a new method to screen hundreds of thousands of molecules for drug discovery, using mass spectrometry instead of DNA tags. ‘We wanted to make drug discovery faster and more accessible.’
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The Nobel Prize in Chemistry went to an AI model (and rightly so)
Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…
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Mario van der SteltFaculty of Science
m.van.der.stelt@chem.leidenuniv.nl | 071 5274768
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UMCs join forces to increase pandemic preparedness
Four university medical centres, including the LUMC, are joining forces to increase pandemic preparedness in the Netherlands.
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Margo DonaFaculty of Science
m.a.dona@biology.leidenuniv.nl | 071 5272727
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Dan XuFaculty of Science
d.xu@liacs.leidenuniv.nl | 071 5277061
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Randal SheppardFaculty of Humanities
r.c.sheppard@hum.leidenuniv.nl | 071 5272656
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Laura de JongFaculty of Science
l.m.de.jong@lacdr.leidenuniv.nl | 071 5272727
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From discovery to business: 'In the lab, we often don't realise that we are working to help an immense number of patients'
'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…
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Corrugated plastic unveils a new design principle for programmable materials
Martin van Hecke en Anne Meeussen publiceren in het tijdschrift Nature over mechanische metamaterialen. Ze hebben een nieuwe klasse multistabiele materialen ontdekt. Dit is gebaseerd op ribbeltjes plastic.
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RARE-NL: LUMC joins consortium to find treatments for rare diseases
RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.
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Can you design super-smart materials with long-term memory that are capable of learning?
That was the question physics and mathematics bachelor’s student Daan de Bos set out to explore during his thesis research. Applying machine learning theories to materials presented several challenges, but his efforts led to a working theory that can now be tested on real materials in laboratories.
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Erik DanenFaculty of Science
e.danen@lacdr.leidenuniv.nl | 071 5274486
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The Design-Thinking method for stimulating knowledge transfer in organisations
Sharing knowledge based on research within organisations presents a challenging task. How can this be done effectively? What steps should be taken to ensure that knowledge obtained from research is shared and applied in the organisation's daily practice? On 8 May, the Leiden Leadership Centre (LLC)…
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Juan Masullo JimenezFaculty of Social and Behavioural Sciences
j.masullo@fsw.leidenuniv.nl | 071 5272727
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Code for children’s rights: Designing technology with children in mind
On Friday 12 March 2021, the (Dutch) website www.codevoorkinderrechten.nl was launched. This code for children’s rights has been created to help those involved in the development and design of digital services to develop these services with the interests of children in mind.
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Roxanne KieltykaFaculty of Science
r.e.kieltyka@chem.leidenuniv.nl | 071 5274441
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Designing the quantum future on a regular computer
Computer scientist Tim Coopmans uses pen, paper and regular computers to simulate the best possible quantum computer. He tells about his research and how this helps make a useful quantum computer a reality a little bit sooner. ‘I hope I will get to see quantum computers contributing something really…
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Creative Call: Help us name and design the logo for our Humanities Labs!
Organisation
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Simone van der Hof in online talk show about Behavioral Design in Video Games
On 7 October 2021 Simone van der Hof participated in an online talk show as part of the Dutch Media Week. The theme was the research project she is working on with Tony van Rooij of the Trimbos Institute and Max Birk of TU Eindhoven: Behavioral Design in Video Games.
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Lecture Simone van der Hof on age verification and age appropriate design
On 6 October 2021, Simone van der Hof gave a lecture on age verification and age appropriate design.
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The molecular secrets of medicinal cannabis
Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…
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Serkan AslanFaculty of Science
s.aslan@lacdr.leidenuniv.nl | 071 5275919
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Sebastian PomplunFaculty of Science
s.j.pomplun@lacdr.leidenuniv.nl | 071 5274651
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Coen van HasseltFaculty of Science
coen.vanhasselt@lacdr.leidenuniv.nl | 071 5273266
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Anthe JanssenFaculty of Science
a.p.a.janssen@lic.leidenuniv.nl | 071 5272727
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Home magazines of yesteryear: Upholsterers were the interior designers of the eighteenth century'
Today, anyone wanting a new look for their living room watches a home decorating programme or buys an interior design magazine. In the eighteenth century, people went to an upholstry specialist, who would provide you with new wall coverings, curtains and much-needed accessories. PhD candidate Aagje…
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Real-life data ask for strong algorithms: Mitra Baratchi designs them
How do we deal with large sources of greenhouse gases? Do schools provide a socially-inclusive environment for all children? And how can we protect Earth’s nature? These questions have two things in common: they are complex global challenges, and data can help answer them. Mitra Baratchi is computer…
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Over a million euros for two studies on solutions to antimicrobial resistance
Two consortia led by Leiden researchers have been awarded over one million euros by the Dutch Research Council and the Ministry of Health, Welfare and Sport to find solutions to antimicrobial resistance.
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Leiden scientists join national effort to advance nanomedicine
A Dutch consortium has received €6.7 million to accelerate the development of nanomedicines together with patients. Researchers from Leiden University play a key role in the project.
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How Oncode-PACT is bringing new cancer medicines closer with 325 million in Growth Fund money
How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…
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Seeking new concepts to treat diseases
Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’
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Thomas HankemeierFaculty of Science
hankemeier@lacdr.leidenuniv.nl | 071 5274226
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Robotic reconstitution of cytostatic drugs and monoclonal antibodies: transforming aseptic drug compounding in hospital pharmacies
PhD defence
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Leiden ‘super antibiotic’ keeps dangerous gut bacterium under control with a low dose
The antibiotic EVG7, developed in Leiden, has proven capable of fighting the dangerous gut bacterium C. difficile with only a minimal dose. What’s more, the bacterium is far less likely to return, a major issue with existing antibiotics. The research was published in Nature Communications.
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‘Never stop trying’: Barz sees his polymers enter clinical trials
A new class of polymers has been used in patients for the first time. The compound is the first new drug solubilising agent in decades. Introduced in 2014 by chemist Matthias Barz from Leiden University, it offers a unique alternative to current options.
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Gerard van Westen Invited as Speaker at Palace Symposium ‘Biological Design Through Artificial Intelligence’ Highlighting a Sustainable Future
AMSTERDAM – On the evening of Tuesday, November 19, the Palace Symposium took place at the Royal Palace Amsterdam, with this year’s theme being ‘Biological Design Through Artificial Intelligence’. His Majesty the King and Her Majesty Queen Máxima hosted the event, and Princess Beatrix was also present…